辐射变色胶片剂量测量模型的选择
Model selection for radiochromic film dosimetry
摘要：
本研究的目的是通过比较不同的通道无关微扰模型，找到最准确的辐射变色胶片剂量学模型。基于（算法）信息理论的模型选择方法，并使用一组基准测试用例的伽马指数分析的结果进行了验证。讨论了几个问题：（a）通过在照射之前扫描而结合未照射的胶片的信息是否改进了结果;（b）当使用多通道模型时是否需要横向校正;（c）多通道剂量测定法是否产生比单通道剂量测定法更好的结果;（d）哪种多通道扰动模型提供更准确的胶片剂量。结果发现，扫描前照射和应用横向校正提高了结果的准确性。对于某些微扰模型，增加颜色通道的数量不会导致更准确的胶片剂量。发现使用截断正态扰动比使用Micke-Mayer扰动模型提供更好的结果。在比较的模型中，三通道模型与截断正常扰动，净光密度作为响应，并受到横向校正的应用被认为是最准确的模型。本研究的范围受到模型测试的限制。在这项研究中，用兆伏放射治疗束照射胶片，剂量约为20 cGy至600 cGy，扫描整个（8 ${\rm inch}$ $\times$ 10 ${\rm inch}$）胶片，感光曲线的函数形式为多项式，并使用基于平面的方法校准不同批次。
英文摘要：
The purpose of this study was to find the most accurate model for radiochromic film dosimetry by comparing different channel independent perturbation models. A model selection approach based on (algorithmic) information theory was followed, and the results were validated using gamma-index analysis on a set of benchmark test cases. Several questions were addressed: (a) whether incorporating the information of the non-irradiated film, by scanning prior to irradiation, improves the results; (b) whether lateral corrections are necessary when using multichannel models; (c) whether multichannel dosimetry produces better results than single-channel dosimetry; (d) which multichannel perturbation model provides more accurate film doses. It was found that scanning prior to irradiation and applying lateral corrections improved the accuracy of the results. For some perturbation models, increasing the number of color channels did not result in more accurate film doses. Employing Truncated Normal perturbations was found to provide better results than using Micke-Mayer perturbation models.} Among the models being compared, the triple-channel model with Truncated Normal perturbations, net optical density as the response and subject to the application of lateral corrections was found to be the most accurate model. The scope of this study was circumscribed by the limits under which the models were tested. In this study, the films were irradiated with megavoltage radiotherapy beams, with doses from about 20 cGy to 600 cGy, entire (8 ${\rm inch}$ $\times$ 10 ${\rm inch}$) films were scanned, the functional form of the sensitometric curves was a polynomial and the different lots were calibrated using the plane-based method.
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