应用视频指导呼吸指导系统的呼吸门控放射治疗中呼吸信号的变化
Variations of the Respiration Signals for Respiratory-Gated Radiotherapy Using the Video Coached Respiration Guiding System
摘要：
呼吸门控放射治疗（RGRT）已被用于最大限度地减少肺癌放疗中正常组织的剂量。本研究旨在通过视频指导呼吸指导系统改善RGRT中的呼吸规律。在这项研究中，16例肺癌患者进行了评估。通过实时位置管理（RPM）呼吸门控系统（Varian，USA）测量患者的呼吸信号，并使用视频指导呼吸指导系统对患者进行培训。患者进行自由呼吸和引导呼吸，采集呼吸周期约5 min。然后，使用Microsoft Excel 2010软件计算每个阶段的平均值和标准差。计算标准差，以分析呼吸规律性相对于周期和位移的改善。与患者6的自由呼吸的值相比，引导呼吸的标准偏差在吸气峰中降低到65.14%，在呼气峰中降低到71.04%。发现使用呼吸引导系统降低了呼吸周期的标准偏差。2应用视频指导呼吸指导系统后，呼吸规律明显改善。因此，该系统对于提高RGRT的精度和效率具有重要意义。
英文摘要：
Respiratory-gated radiation therapy (RGRT) has been used to minimize the dose to normal tissue in lung-cancer radiotherapy. The present research aims to improve the regularity of respiration in RGRT using a video coached respiration guiding system. In the study, 16 patients with lung cancer were evaluated. The respiration signals of the patients were measured by a real-time position management (RPM) Respiratory Gating System (Varian, USA) and the patients were trained using the video coached respiration guiding system. The patients performed free breathing and guided breathing, and the respiratory cycles were acquired for ~5 min. Then, Microsoft Excel 2010 software was used to calculate the mean and standard deviation for each phase. The standard deviation was computed in order to analyze the improvement in the respiratory regularity with respect to the period and displacement. The standard deviation of the guided breathing decreased to 65.14% in the inhale peak and 71.04% in the exhale peak compared with the values for the free breathing of patient 6. It was found that the standard deviation of the respiratory cycle was decreased using the respiratory guiding system. 2 The respiratory regularity was significantly improved using the video coached respiration guiding system. Therefore, the system is useful for improving the accuracy and efficiency of RGRT.
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