arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 1503.01724physics.med-ph
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蒙特卡罗剂量计算用的解析直线加速器源模型。I.模型表示和构造

An Analytic Linear Accelerator Source Model for Monte Carlo Dose Calculations. I. Model Representation and Construction

Zhen Tian, Yongbao Li, Michael Folkerts, Feng Shi, Steve B. Jiang, Xun Jia

摘要:

蒙特卡罗(MC)模拟被认为是辐射剂量计算中最精确的方法。直线加速器的源模型的准确性对于总体剂量计算准确性是关键的。在本文中,我们提出了一个分析源模型,我们最近开发的基于GPU的MC剂量计算。提出了相空间环的概念。它包含一组粒子,这些粒子具有相同的类型,并且在能量和径向距离上接近相空间平面的中心。该模型参数化了每个初级光子PSR、散射光子PSR和电子PSR的粒子位置、方向和能量的概率密度。对于初级光子PSR,粒子方向被假设为来自束斑。有限的光斑尺寸用2D高斯分布建模。对于散射光子PSR,使用多个高斯分量来模拟粒子方向。电子PSR的方向分布也被建模为具有大的标准偏差的2D高斯分布。我们还开发了一种方法来分析相空间文件,并获得相应的模型参数。为了测试我们的直线加速器源模型的准确性,不同的开放领域的水幻影的剂量分布计算使用我们的源模型,并与直接计算使用参考相空间文件。对于积聚区和射束半影区的深度剂量,平均一致距离(DTA)在1 mm以内。内、外射束区剂量分布的均方根(RMS)剂量差在1.1%以内。输出因子的最大相对差异在0.5%以内。在调强放射治疗前列腺患者病例和调强放射治疗头颈部病例中也发现了良好的一致性。这些结果证明了我们的源模型在准确表示参考相空间文件方面的有效性。

英文摘要:

Monte Carlo (MC) simulation is considered as the most accurate method for radiation dose calculations. Accuracy of a source model for a linear accelerator is critical for the overall dose calculation accuracy. In this paper, we presented an analytical source model that we recently developed for GPU-based MC dose calculations. A key concept called phase-space-ring (PSR) was proposed. It contained a group of particles that are of the same type and close in energy and radial distance to the center of the phase-space plane. The model parameterized probability densities of particle location, direction and energy for each primary photon PSR, scattered photon PSR and electron PSR. For a primary photon PSRs, the particle direction is assumed to be from the beam spot. A finite spot size is modeled with a 2D Gaussian distribution. For a scattered photon PSR, multiple Gaussian components were used to model the particle direction. The direction distribution of an electron PSRs was also modeled as a 2D Gaussian distribution with a large standard deviation. We also developed a method to analyze a phase-space file and derive corresponding model parameters. To test the accuracy of our linac source model, dose distributions of different open fields in a water phantom were calculated using our source model and compared to those directly calculated using the reference phase-space file. The average distance-to-agreement (DTA) was within 1 mm for the depth dose in the build-up region and beam penumbra regions. The root-mean-square (RMS) dose difference was within 1.1% for dose profiles at inner and outer beam regions. The maximal relative difference of output factors was within 0.5%. Good agreements were also found in an IMRT prostate patient case and an IMRT head-and-neck case. These results demonstrated the efficacy of our source model in terms of accurately representing a reference phase-space file.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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