Monte Carlo (MC) simulation is considered as the most accurate method for radiation dose calculations. Accuracy of a source model for a linear accelerator is critical for the overall dose calculation accuracy. In this paper, we presented an analytical source model that we recently developed for GPU-based MC dose calculations. A key concept called phase-space-ring (PSR) was proposed. It contained a group of particles that are of the same type and close in energy and radial distance to the center of the phase-space plane. The model parameterized probability densities of particle location, direction and energy for each primary photon PSR, scattered photon PSR and electron PSR. For a primary photon PSRs, the particle direction is assumed to be from the beam spot. A finite spot size is modeled with a 2D Gaussian distribution. For a scattered photon PSR, multiple Gaussian components were used to model the particle direction. The direction distribution of an electron PSRs was also modeled as a 2D Gaussian distribution with a large standard deviation. We also developed a method to analyze a phase-space file and derive corresponding model parameters. To test the accuracy of our linac source model, dose distributions of different open fields in a water phantom were calculated using our source model and compared to those directly calculated using the reference phase-space file. The average distance-to-agreement (DTA) was within 1 mm for the depth dose in the build-up region and beam penumbra regions. The root-mean-square (RMS) dose difference was within 1.1% for dose profiles at inner and outer beam regions. The maximal relative difference of output factors was within 0.5%. Good agreements were also found in an IMRT prostate patient case and an IMRT head-and-neck case. These results demonstrated the efficacy of our source model in terms of accurately representing a reference phase-space file.
An Analytic Linear Accelerator Source Model for Monte Carlo dose calculations. II. Model Utilization in a GPU-based Monte Carlo Package and Automatic Source Commissioning
Non-invasive Reversible Software-based Electron FLASH Irradiation Configuration of a Linear Accelerator in Clinical Use
Stanford University School of Medicine(斯坦福大学医学院);University of California Irvine(加州大学尔湾分校);Princess Margaret Cancer Centre, University Health Network(公主玛格丽特癌症中心,联合健康网络)
Monte Carlo Simulation of 6MV Elekta Synergy Platform Linac photon beam using Gate/Geant4
本工作致力于开发一个计算模型,使用门蒙特卡罗软件模拟Elekta Synergy平台医用直线加速器治疗头提供的6 MV光子束。该模型包括多叶加速器头的主要组件和均质水模体。对光子束进行了计算,在距离源100 cm处,几个治疗野的尺寸范围为5*5 cm 2至30*30 cm 2。通过与哈桑二世区域肿瘤中心测量的实验分布进行比较,成功地验证了模拟。模拟和测量之间的良好协议进行了观察,剂量差异约为1.6%和1.8%的深度剂量和横向剂量分布,分别。还进行了伽马指数比较,其中所有模拟的98%以上的点通过了3 mm/3%的标准质量保证标准。
Laboratory Report (LR) to the paper Foundation of an analytical proton beamlet model for inclusion in a general proton dose calculation system [arXiv:1009.0832]
Addressing respiratory gating latency for accurate pulse delivery in preclinical electron FLASH irradiation on a clinical linear accelerator
Stanford University School of Medicine(斯坦福大学医学院);Varian Medical Systems(瓦里安医疗系统);The University of Texas MD Anderson Cancer Center(德克萨斯大学安德森癌症中心);University of California Irvine School of Medicine(加州大学欧文分校医学院)
PyDoseRT Proton: A GPU Pencil-Beam Engine with a Convolutional Residual-Correction Network for Fast Proton Dose Calculation
Medical University of Vienna(维也纳医科大学);Christian Doppler Laboratory for Image and Knowledge Driven Precision Radiation Oncology(克里斯蒂安·多普勒图像与知识驱动精准放射肿瘤学实验室);Umeå University(于默奥大学)
OpenPINT: Open-source Planning for Isoeffective Nuclear Treatments in BNCT research
Istituto Nazionale di Fisica Nucleare, unit of Pavia(意大利国家核物理研究所帕维亚分部);Comisión Nacional de Energía Atómica, CNEA(阿根廷国家原子能委员会);Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET(阿根廷国家科学研究委员会);Universidad Nacional de San Martín(圣马丁国立大学);Università degli studi di Pavia, Dipartimento di Fisica “Alessandro Volta”(帕维亚大学亚历山德罗·伏打物理系)
Potential pof laser-driven VHEEs towards FLASH radiotherapy: Monte Carlo dosimetric study of single-field pencil beam scanning of a brain tumor
Intense Laser Irradiation Laboratory, CNR-INO(强激光辐照实验室,CNR-INO);Istituto Nazionale di Fisica Nucleare, Sezione di Pisa(意大利国家核物理研究所,比萨分部);Clinica S.Rossore(S.Rossore诊所);CNR-IFC;Lawrence Berkeley National Laboratory(劳伦斯伯克利国家实验室)
Charge Collection Efficiency in Air-Vented Plane-Parallel Ionisation Chambers at Ultra-High Dose Rates: A Self-Consistent Garfield++ Monte Carlo Model Including Space-Charge Effects and Ion Recombination
Université libre de Bruxelles (ULB)(布鲁塞尔自由大学);Ion Beam Applications SA(离子束应用公司)