系统生物学：从细胞到大脑
Systems biology: From the cell to the brain
摘要：
随着人类基因组图谱的完成，科学家们试图解释生命系统的生物复杂性的重点正在从分析单个组件（如特定的基因或生化反应）转移到理解大量组件之间的相互作用，这些组件导致生物体的不同功能。为此，系统生物学领域试图通过关注相互作用网络而不是其孤立部分的特征来实现对生物学的“系统级”描述。在这篇文章中，我们简要描述了一些新兴的主题研究“网络”生物学，着眼于动态过程发生在两个不同的长度尺度的细胞内和细胞之间，即，细胞内信号网络和神经系统。我们表明，专注于这些问题的系统级方面，可以观察到令人惊讶的和启发性的共同主题。
英文摘要：
With the completion of human genome mapping, the focus of scientists seeking to explain the biological complexity of living systems is shifting from analyzing the individual components (such as a particular gene or biochemical reaction) to understanding the set of interactions amongst the large number of components that results in the different functions of the organism. To this end, the area of systems biology attempts to achieve a "systems-level" description of biology by focusing on the network of interactions instead of the characteristics of its isolated parts. In this article, we briefly describe some of the emerging themes of research in "network" biology, looking at dynamical processes occurring at the two different length scales of within the cell and between cells, viz., the intra-cellular signaling network and the nervous system. We show that focusing on the systems-level aspects of these problems allows one to observe surprising and illuminating common themes amongst them.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
