基于实验数据校准尺寸结构种群模型
On the Calibration of a Size-Structured Population Model from Experimental Data
AI总结:
本文综述并实现了从细胞体积分布数据重建分裂率的方法,并通过大肠杆菌实验数据验证了理论结果。
摘要:
本工作的目标是双重的。首先,我们综述了(Perthame, Zubelli, 2007)和(Doumic, Perthame, Zubelli, 2008)中发展的技术,用于从某些结构种群模型中的细胞体积分布数据重建分裂(出生)率。其次,我们将这些技术应用于文献中可用的实验细胞体积分布,以验证理论和数值结果。作为概念验证,我们使用了Kubitschek [3]经典工作中报道的数据,这些数据涉及通过Coulter传感器-多通道分析仪系统(Coulter Electronics, Inc., Hialeah, Fla, USA)测量的大肠杆菌体外实验。尽管测量技术较为陈旧,重建的分裂率仍然显示出潜在有用的生物学特征。
英文摘要:
The aim of this work is twofold. First, we survey the techniques developed in (Perthame, Zubelli, 2007) and (Doumic, Perthame, Zubelli, 2008) to reconstruct the division (birth) rate from the cell volume distribution data in certain structured population models. Secondly, we implement such techniques on experimental cell volume distributions available in the literature so as to validate the theoretical and numerical results. As a proof of concept, we use the data reported in the classical work of Kubitschek [3] concerning Escherichia coli in vitro experiments measured by means of a Coulter transducer-multichannel analyzer system (Coulter Electronics, Inc., Hialeah, Fla, USA.) Despite the rather old measurement technology, the reconstructed division rates still display potentially useful biological features.
机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。