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arXiv 0907.3160cond-mat.stat-mechq-bio.SC
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干扰对纳米通道非平衡输运时间的影响

Effects of jamming on non-equilibrium transport times in nano-channels

Anton Zilman, John Pearson, Golan Bel

摘要:

许多生物通道执行高度选择性的运输,而不直接输入代谢能量,并且在运输期间不从“封闭”状态转变为“开放”状态。这种通道的选择性机制为创建人工纳米分子分选装置和生物传感器提供了灵感。为了阐明传输机制,重要的是要了解单分子水平上的传输在实验相关的制度时,多个粒子拥挤在通道中。本文用解析理论和计算机模拟的方法分析了粒子间拥挤效应对有限长通道非平衡输运时间的影响。

英文摘要:

Many biological channels perform highly selective transport without direct input of metabolic energy and without transitions from a 'closed' to an 'open' state during transport. Mechanisms of selectivity of such channels serve as an inspiration for creation of artificial nano-molecular sorting devices and bio-sensors. To elucidate the transport mechanisms, it is important to understand the transport on the single molecule level in the experimentally relevant regime when multiple particles are crowded in the channel. In this paper we analyze the effects of inter-particle crowding on the non-equilibrium transport times through a finite-length channel by means of analytical theory and computer simulations.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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