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arXiv 0902.4773math.PRq-bio.PE
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多型分枝过程的频率

Relative frequencies in multitype branching processes

Andrei Y. Yakovlev, Nikolay M. Yanev

摘要:

本文研究多型分枝过程中不同类型个体的频率。我们证明了当初始祖先数较大且观测时间固定时,频率是渐近多元正态的。这个结果对任何类型有限的分支过程都是有效的;唯一需要的假设是独立的个体演化。所考虑的问题是由细胞生物学领域的应用所激发的。具体而言,报告的限制性结果在细胞动力学研究中是有利的,其中频率而不是绝对细胞计数可用于测量。相关的统计应用的背景下,讨论了多型分支过程的渐近最大似然推断。

英文摘要:

This paper considers the relative frequencies of distinct types of individuals in multitype branching processes. We prove that the frequencies are asymptotically multivariate normal when the initial number of ancestors is large and the time of observation is fixed. The result is valid for any branching process with a finite number of types; the only assumption required is that of independent individual evolutions. The problem under consideration is motivated by applications in the area of cell biology. Specifically, the reported limiting results are of advantage in cell kinetics studies where the relative frequencies but not the absolute cell counts are accessible to measurement. Relevant statistical applications are discussed in the context of asymptotic maximum likelihood inference for multitype branching processes.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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