所有球形病毒都具有二十面体对称性吗？
Do All Spherical Viruses Have Icosahedral Symmetry?
摘要：
具有12、32和72个亚基的病毒衣壳（$T1$、$T3$和$T7$病毒）的最新高分辨率结构已经证实了具有12个亚基具有5个最近邻亚基（五聚体）和$(10T+2)-12$亚基具有6个最近邻亚基（六聚体）的二十面体结构的理论预测。在此，我们注意到$T4$、$T9$ $T16$和$T25$病毒的能量应变的理论考虑通过对齐的五聚体和能量应变以及随着亚基数目的增长五聚体的可能排列的绝对数目，对如此数量的亚基的模拟使得二十偏四面体构型要么奇迹般地不可能，要么表明自然界中一定存在前所未有的保真度的衣壳组装原理。例如，我们预测高分辨率数据将显示$T4$衣壳具有$D_{5h}$而不是二十面体对称性。
英文摘要：
Recent high resolution structures for viral capsids with 12, 32 and 72 subunits ($T1$, $T3$ and $T7$ viruses) have confirmed theoretical predictions of an icosadeltahedral structure with 12 subunits having five nearest neighbors (pentamers) and $(10T+2)-12$ subunits having six nearest neighbor subunits (hexamers). Here we note that theoretical considerations of energy strain for $T4$, $T9$ $T16$ and $T25$ viruses by aligned pentamers and energy strain along with the sheer number of possible arrangement of pentamers as the number of subunits grows, and simulations for such numbers of subunits make an icosadeltahedral configuration either miraculously unlikely or indicate that there must be a principle of capsid assembly of unprecedented fidelity in Nature. We predict, for example, that high resolution data will show $T4$ capsids to have $D_{5h}$ not icosahedral symmetry.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
