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arXiv physics/9802043physics.bio-phq-bio
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Peyrard-Bishop模型应用于非常短的DNA熔化的第一次实验测试

First experimental tests of the Peyrard-Bishop model applied to the melting of very short DNAs

Alessandro Campa, Andrea Giansanti

备注：
8 pages, Latex, 1 figure, submitted to Phys. Rev. E
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摘要：

根据统计热力学理论计算了短链异质DNA在溶液中的熔解曲线，并与实验结果进行了比较。配分函数的计算基于Peyrard-Bishop哈密顿量，该哈密顿量已经被用于长DNA链解链的理论描述中。在短链的情况下，不仅需要考虑单碱基对之间氢键的断裂，而且需要考虑形成双螺旋的两条链的完全解离。

英文摘要：

The melting curves of short heterogeneous DNA chains in solution are calculated on the basis of statistical thermodynamics and compared to experiments. The computation of the partition function is based on the Peyrard-Bishop hamiltonian, which has already been adopted in the theoretical description of the melting of long DNA chains. In the case of short chains it is necessary to consider not only the breaking of the hydrogen bonds between single base pairs, but also the complete dissociation of the two strands forming the double helix.

机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。

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