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arXiv physics/0701188physics.med-phphysics.ins-det
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微特斯拉磁场下的并行MRI

Parallel MRI at microtesla fields

V. S. Zotev, P. L. Volegov, A. N. Matlashov, M. A. Espy, J. C. Mosher, R. H. Kraus

摘要:

并行成像技术已广泛应用于高场磁共振成像(MRI)中。多个接收器线圈已被证明可以提高图像质量并允许加速图像采集。超低场磁共振成像是一种新型的成像方法,它利用超导量子干涉仪(SQUID)传感器在微泰斯拉测量场测量预极化核自旋布居的空间编码进动。在这项工作中,并行成像在微特斯拉领域的首次系统研究。设计用于ULF MRI和脑磁图(MEG)的七通道SQUID系统用于采集人手的3D图像以及大型水模的2D图像。在46微特斯拉测量场下进行成像,预极化为40 mT。它示出了如何使用七个通道增加成像视场和改善信噪比的手图像。一个简单的程序近似校正伴随梯度伪影。对噪声传播进行了实验分析,找出了相关噪声的主要来源。在二维体模的情况下,研究了基于一维欠采样和一维SENSE(灵敏度编码)图像重建的加速成像。实际的3倍成像加速度相比,单平均完全编码傅立叶成像证明。这些结果表明,并行成像方法在ULF MRI中是有效的,并且基于SQUID的仪器的成像性能随着通道数量的增加而显著提高。

英文摘要:

Parallel imaging techniques have been widely used in high-field magnetic resonance imaging (MRI). Multiple receiver coils have been shown to improve image quality and allow accelerated image acquisition. Magnetic resonance imaging at ultra-low fields (ULF MRI) is a new imaging approach that uses SQUID (superconducting quantum interference device) sensors to measure the spatially encoded precession of pre-polarized nuclear spin populations at microtesla-range measurement fields. In this work, parallel imaging at microtesla fields is systematically studied for the first time. A seven-channel SQUID system, designed for both ULF MRI and magnetoencephalography (MEG), is used to acquire 3D images of a human hand, as well as 2D images of a large water phantom. The imaging is performed at 46 microtesla measurement field with pre-polarization at 40 mT. It is shown how the use of seven channels increases imaging field of view and improves signal-to-noise ratio for the hand images. A simple procedure for approximate correction of concomitant gradient artifacts is described. Noise propagation is analyzed experimentally, and the main source of correlated noise is identified. Accelerated imaging based on one-dimensional undersampling and 1D SENSE (sensitivity encoding) image reconstruction is studied in the case of the 2D phantom. Actual 3-fold imaging acceleration in comparison to single-average fully encoded Fourier imaging is demonstrated. These results show that parallel imaging methods are efficient in ULF MRI, and that imaging performance of SQUID-based instruments improves substantially as the number of channels is increased.

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