细胞骨架蛋白量子效应的实验研究
Towards Experimental Tests of Quantum Effects in Cytoskeletal Proteins
摘要：
越来越明显的是，通过分子自组装制备新型生物材料将在材料科学和未来的信息技术中发挥重要作用。微管蛋白，微管（MT）和细胞骨架是动态的，自组装系统，我们问他们的结构和功能是否包含如何制造生物分子信息处理设备的线索。在这里，我们回顾我们的转基因果蝇的神经生物学研究，强烈建议微管细胞骨架是细胞内信息处理和存储的“前线”附近。我们还建立了光谱技术，如折射率，表面等离子体共振传感和介电光谱，再加上分子动力学模拟和（量子）电动力学分析理论是有用的工具，在电动力学和可能的量子效应在细胞骨架蛋白质的研究。在我们的驱动问题中隐含的可能性是，如果微管蛋白和MT确实可以作为经典或量子计算机的基础，那么也许大自然已经这样做了，微管蛋白和MT已经在活的神经细胞和其他细胞中发挥了这样的作用。如果发现量子力学在细胞功能中很重要（通过它与蛋白质的关系），那么很自然地会问，是否真的存在与意识相关的量子效应。最后，我们提出了一些方法来直接在蛋白质水平上对这种“量子意识思想”（QCI）进行实验测试。
英文摘要：
It has become increasingly evident that fabrication of novel biomaterials through molecular self-assembly is going to play a significant role in material science and possibly the information technology of the future. Tubulin, microtubules (MTs) and the cytoskeleton are dynamic, self-assembling systems and we asked whether their structure and function contain the clues on how to fabricate biomolecular information processing devices. Here we review our neurobiological studies of transgenic Drosophila that strongly suggest the microtubular cytoskeleton is near the 'front lines' of intracellular information manipulation and storage. We also establish that spectroscopic techniques such as refractometry, surface plasmon resonance sensing and dielectric spectroscopy, coupled with molecular dynamic simulations and (quantum) electrodynamic analytical theory are useful tools in the study of the electrodynamic and possible quantum effects in cytoskeletal proteins. Implicit in our driving question is the possibility that if tubulin and MTs can indeed be cast as the basis of a classical or quantum computer, then perhaps nature has already done so and tubulin and MTs already play such a role in living neural and other cells. If quantum mechanics is found to be important in cellular function (through its involvement in proteins) it is natural to ask whether there are indeed quantum effects pertinent to consciousness. We conclude this work by suggesting a number of ways towards experimentally testing this "Quantum Consciousness Idea" (QCI), directly at the protein level.
机构、总结、中文摘要均由AI分析而来，可能存在错误，请以论文正文为准。
