微管蛋白偶极矩、介电常数和量子行为：计算机模拟、实验结果和建议
Tubulin dipole moment, dielectric constant and quantum behavior: computer simulations, experimental results and suggestions
摘要：
我们使用计算机模拟来计算α和β微管蛋白单体和二聚体的电偶极矩，并发现它们是|palpha| = 552 D，|pbeta| = 1193 D，|α-β| =1740D。对高频介电常数和极化率的独立表面等离子体共振（SPR）和折射率测量强烈证实了我们先前SPR导出的结果，得到Δ n/Δ c约为1.800 x10 ^-3 ml/mg。微管蛋白的折射率被测得为n_tub ~2.90，高频微管蛋白介电常数kappa_tub ~8.41，而高频极化率被测得为α_tub ~ 2.1 × 10 ^-33 C m^2/V。频率p以及测试微管蛋白的经常受到限制的量子相干性和纠缠特性的方法。讨论了生物比特、生物量子比特和其他生物电子学应用。
英文摘要：
We used computer simulation to calculate the electric dipole moments of the alpha and beta tubulin monomers and dimer and found those to be |palpha|=552D, |pbeta|=1193D and |palpha-beta|=1740D respectively. Independent surface plasmon resonance (SPR) and refractometry measurements of the high-frequency dielectric constant and polarizability strongly corroborated our previous SPR-derived results giving delta-n/delta-c ~1.800x10^-3 ml/mg. The refractive index of tubulin was measured to be n_tub ~2.90 and the high frequency tubulin dielectric constant kappa_tub ~8.41 while the high-frequency polarizability was found to be alpha_tub ~ 2.1x10^-33 C m^2/V. Methods for the experimental determination of the low-frequency p are explored as well as ways to test the often conjectured quantum coherence and entanglement properties of tubulin. Biobits, bioqubits and other applications to bioelectronics are discussed.
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