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arXiv physics/0301028physics.bio-phcond-mat.softphysics.class-phq-bio
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开口DNA的扭转几何

Writhing Geometry of Open DNA

V. Rossetto, A. C. Maggs

摘要:

最近的DNA扭转力的延伸特性的实验的动机,我们认为开放的刚性分子的扭曲几何。我们展示了一个周期性的运动,它允许任意大的扭曲的分子通过一个激活的过程结束。这一过程被抑制的力量大于毫微微牛顿,这使我们能够表明,实验是敏感的Calucianu-White公式的扭曲的推广。使用数值方法,我们比较这个配方的扭动与最近的分析计算。

英文摘要:

Motivated by recent experiments on DNA torsion-force-extension characteristics we consider the writhing geometry of open stiff molecules. We exhibit a cyclic motion which allows arbitrarily large twisting of the end of a molecule via an activated process. This process is suppressed for forces larger than femto-Newtons which allows us to show that experiments are sensitive to a generalization of the Calugareanu-White formula for the writhe. Using numerical methods we compare this formulation of the writhe with recent analytic calculations.

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