S-DNA的弯曲刚度
The bend stiffness of S-DNA
摘要:
我们制定和解决一个两态模型的弹性缺口,双链DNA,借用功能从蠕虫状链和布拉格-齐姆模型。我们的模型计算简单,并通过整个过度拉伸过渡给出了一个很好的适合最近的实验数据。拟合给出了过度拉伸状态的弯曲刚度的第一个值,约为10 nm*kbt,这一值与B型或单链DNA完全不同。
英文摘要:
We formulate and solve a two-state model for the elasticity of nicked, double-stranded DNA that borrows features from both the Worm Like Chain and the Bragg--Zimm model. Our model is computationally simple, and gives an excellent fit to recent experimental data through the entire overstretching transition. The fit gives the first value for the bending stiffness of the overstretched state as about 10 nm*kbt, a value quite different from either B-form or single-stranded DNA.
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