考虑一个通过可交换的繁殖动力学进化的单倍体种群,其中所有在时间$t$存活的个体都有一个最近的共同祖先(MRCA),他们生活在时间$A_t$。随着时间的推移,不仅人口会发生变化,而且其谱系也会发生变化:一些家庭将从人口中消失,最终将建立新的MRCA。对于一个时间平稳的情况下,并在无穷总体规模$N$与时间测量的$N$代,即在缩放的人口遗传学,导致费舍尔-赖特扩散和金曼的合并,我们研究的过程$\mathcal A = (A_t)$的跳跃形成的点过程的时间对$(E,B)$时,新的MRCA建立,当他们住。通过将这些粒子对表示为粒子的进入和离开时间,这些粒子的轨迹嵌入Donnelly和Kurtz(1999)的俯视图中,我们可以通过交换论证来证明泊松过程的时间$E$和时间$B$。此外,粒子表示有助于计算MRCA过程的各种特征,例如建立新MRCA时聚结的分布,以及今天过去的MRCA数量的分布。
英文摘要:
Consider a haploid population which has evolved through an exchangeable reproduction dynamics, and in which all individuals alive at time $t$ have a most recent common ancestor (MRCA) who lived at time $A_t$, say. As time goes on, not only the population but also its genealogy evolves: some families will get lost from the population and eventually a new MRCA will be established. For a time-stationary situation and in the limit of infinite population size $N$ with time measured in $N$ generations, i.e. in the scaling of population genetics which leads to Fisher-Wright diffusions and Kingman's coalescent, we study the process $\mathcal A = (A_t)$ whose jumps form the point process of time pairs $(E,B)$ when new MRCAs are established and when they lived. By representing these pairs as the entrance and exit time of particles whose trajectories are embedded in the look-down graph of Donnelly and Kurtz (1999) we can show by exchangeability arguments that the times $E$ as well as the times $B$ from a Poisson process. Furthermore, the particle representation helps to compute various features of the MRCA process, such as the distribution of the coalescent at the instant when a new MRCA is established, and the distribution of the number of MRCAs to come that live in today's past.
Inference with selection, varying population size and evolving population structure: Application of ABC to a forward-backward coalescent process with interactions
Center for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, PSL Research University(跨学科生物学研究中心,法兰西学院,法国国家科学研究中心,法国国家健康与医学研究院,PSL研究大学);Laboratoire de Probabilités, Statistique et Modélisation (LPSM), Sorbonne Université, CNRS(概率、统计与建模实验室,索邦大学,法国国家科学研究中心);Institut de Systématique, Évolution, Biodiversité (ISYEB), MNHN, CNRS, Sorbonne Université(系统分类学、进化与生物多样性研究所,法国国家自然历史博物馆,法国国家科学研究中心,索邦大学)
Genetic contribution of advantaged ancestors in the biparental Moran model -- finite selection
Université Paris-Saclay, AgroParisTech, INRAE, UMR MIA Paris-Saclay(巴黎萨克雷大学、农业巴黎技术学院、法国国家农业食品环境研究院);Université Paris-Saclay, CNRS, Laboratoire de mathématiques d’Orsay(巴黎萨克雷大学、法国国家科学研究中心)
Evolving genealogies in cultural evolution, the descendant process, and the number of cultural traits
School of Interdisciplinary Mathematical Sciences(交叉数理科学学院);Research Center for Integrative Evolutionary Science, SOKENDAI (The Graduate University for Advanced Studies)(前沿科学研究中心,SOKENDAI(advanced studies大学));Kochi University of Technology(高知工科大学);Faculty of Technology, Bielefeld University(比勒费尔德大学技术学院)