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arXiv 2607.00201cs.CV
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信任先验(或不信任):不确定性感知的腹主动脉瘤分割

Trust the Prior (or Not): Uncertainty-Aware Abdominal Aortic Aneurysm Segmentation

Department of Computer Science University of Trento(计算机科学系特伦托大学);Medical Physics Unit Santa Chiara Hospital(圣切拉医院医学物理部)

Erich Robbi, Daniele Ravanelli, Andrea Passerini

AI总结:

针对腹主动脉瘤内腔血栓分割中异质性和域偏移问题,提出结合判别学习与解剖先验的患者特定框架,通过高斯混合模型归一化和不确定性门控解剖注意力模块实现鲁棒分割。

摘要:

内腔血栓的鲁棒分割对于腹主动脉瘤的风险评估至关重要,但由于血栓特征的异质性和与周围非增强组织的低对比度,这一任务仍然具有挑战性。不同计算机断层扫描血管造影(CTA)协议引起的域偏移进一步抑制了深度学习模型的多中心泛化。为了解决这些挑战,我们提出了一个患者特定框架,将判别学习与解剖信息先验相结合。我们的方法引入了两个关键组件:(1)基于局部解剖高斯混合模型的患者特定强度归一化,以及(2)不确定性门控解剖注意力模块,该模块整合空间先验,同时根据体素置信度自适应地调节其影响。这种设计允许在模糊区域进行解剖引导,同时抑制不可靠的先验。所提出的方法在分布内测试数据上实现了最先进的性能,并且在外部多中心CTA数据的泛化中显著优于现有替代方案,同时通过视觉和解剖证据的显式分离保持可解释性。

英文摘要:

Robust segmentation of intraluminal thrombus is critical for risk assessment in Abdominal Aortic Aneurysm, yet it remains challenging due to heterogeneous thrombus features and low contrast with surrounding non-enhanced tissues. Domain shifts induced by different Computed Tomography Angiography (CTA) protocols further inhibit multi-center generalization of deep learning models. To address these challenges, we propose a patient-specific framework that integrates discriminative learning with anatomically informed priors. Our approach introduces two key components: (1) a patient-specific intensity normalization based on a Gaussian Mixture Model of local anatomy, and (2) an Uncertainty-Gated Anatomical Attention module that incorporates spatial priors while adaptively modulating their influence according to voxel-wise confidence. This design allows for anatomical guidance in ambiguous regions while suppressing unreliable priors. The proposed method achieves state-of-the-art performance on in-distribution test data and substantially outperforms existing alternatives in generalization to external multi-center CTA data, while remaining interpretable through an explicit separation of visual and anatomical evidence.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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