To trace or not to trace: analytical insights from network-based contact-tracing models
Tampere University(坦佩雷大学);University of Trento(特伦托大学);Universidad Nacional Autonóma de México(墨西哥国立自治大学);Eötvös Loránd University(厄特沃什·罗兰大学);National Laboratory for Health Security(国家健康安全实验室);Northeastern University London(东北大学伦敦分校);Northeastern University(东北大学)
Giulia de Meijere, Andrea Pugliese, Gerardo Iñiguez, Péter L. Simon, István Z. Kiss
Contact tracing is one of the most important control measures deployed during epidemics. Relying on the identification of contacts of known infected individuals, it necessitates a network perspective. Although pairwise models have been used extensively to study contact tracing, their analysis typically depends on a decoupling assumption-most commonly that contact tracing operates on a much faster timescale than disease transmission. Furthermore, contact tracing models often assume that all infected individuals become contact tracing-triggering, which is unrealistic given partial compliance to treatment. We relax both of these restrictive assumptions and provide a full analytical characterisation of the epidemic threshold in the pairwise mean-field model. Our analysis uses a fast-variables approach that captures the rapid early stabilisation of key network quantities. Inspired by mechanisms from social adoption dynamics, we introduce triplewise contact tracing in which an infected individual can be traced not only through direct contact with a single tracing-triggering neighbor (pairwise tracing), but also indirectly when connected to two tracing-triggering nodes simultaneously. For pure pairwise and pure triplewise contact tracing, we derive analytical expressions for critical contact tracing levels and demonstrate that when many infected individuals bypass treatment, the epidemic can become uncontrollable. When both contact tracing mechanisms operate together, we map out their combined contribution and relative impact on epidemic control. This unified framework yields rigorous and tractable threshold conditions for contact tracing dynamics on networks, extending the applicability of pairwise models beyond the fast-tracing regime and providing new insight into the interplay between disease progression, partial treatment compliance, and higher-order tracing processes.
Effectiveness of probabilistic contact tracing in epidemic containment: the role of super-spreaders and transmission path reconstruction
Politecnico di Torino(都灵理工大学);Italian Institute for Genomic Medicine(意大利基因组医学研究所);Politecnico di Milano(米兰理工大学);Universidad Complutense(康普顿斯大学);Collegio Carlo Alberto(卡洛·阿尔贝托学院)