单晶Au(111)微板提供了一个超光滑、低缺陷的平台，用于可重复的等离子体纳米腔。本文实现了由周期性排列的圆环V槽腔组成的反射模式声学表面器件，这些腔体被铣刻在光学厚的Au微板上，并表征了其可见-近红外响应。测量的光谱显示出窄而深度可调的Fano-like反射最小值，具有弱的方位依赖性，通过四分之一单元有限元建模可重现，与强的间隙-表面等离子体限制一致。对于折射率传感，模拟结果显示出高达约598 nm RIU⁻¹的体灵敏度和高达约33（六边形晶格）的灵敏度因子。作为基于模型的示例，一个针对疟疾快速诊断测试中常见靶标的乳酸脱氢酶（PfLDH）的功能化结构，在所采用的噪声底限下，估计检测限为0.016 nM（≈0.56 ng mL⁻¹）。
英文摘要：
Single-crystal Au(111) microplates provide an ultra-smooth, low-defect platform for reproducible plasmonic nanocavities. Here we realize reflection-mode whispering-gallery metasurfaces comprising periodic arrays of circular V-groove cavities milled into optically thick Au microplates and characterize their visible--near-IR response. The measured spectra exhibit narrow, depth-tunable Fano-like reflectance minima with weak azimuthal dependence, reproduced by quarter-cell finite-element modeling consistent with strong gap-surface-plasmon confinement. For refractometric sensing, simulations yield bulk sensitivities up to $\sim 598$ nm RIU$^{-1}$ and figures of merit up to $\sim 33$ (hexagonal lattice). As a model-based illustration, a functionalized architecture targeting \textit{Plasmodium falciparum} lactate dehydrogenase (PfLDH), a common malaria target of rapid diagnostic tests, gives an estimated limit of detection of $0.016$ nM ($\sim 0.56$ ng mL$^{-1}$) under the adopted noise floor.
Synthesis of hybrid gold-protein nanobioconjugates with strongly enhanced circular dichroism
Sorbonne Universit\' e , CNRS, Institut des NanoSciences de Paris, INSP, F-75252 Paris, France；Sorbonne Universit\' e , CNRS, Laboratoire de R\'eactivit\'e de Surface, LRS, F-75252 Paris, France；Sorbonne Universit\' e , CNRS, Institut Parisien de Chimie Mol\'eculaire, IPCM, F-75252 Paris, France；Aix-Marseille Universit\' e , CNRS, Centrale Marseille, Institut Fresnel, 13013 Marseille, France
A ferroelectric liquid crystal confined in cylindrical nanopores: Reversible smectic layer buckling, enhanced light rotation and extremely fast electro-optically active Goldstone excitations
