AI 中文总结
研究利用纳米光子学控制手性光-物质相互作用，通过金纳米颗粒与光合蛋白静电耦合形成混合纳米生物共轭物，结合数值模拟和测量，发现可增强圆二色性，揭示三种效应，为相关领域开辟新途径。
AI 中文摘要
利用纳米光子学控制手性光-物质相互作用是一种将分子圆二色性（CD）放大到自然极限之外的有力策略。在此，我们展示了一个等离子体平台，该平台利用超手性近场来放大生物发色团的光学活性。直径3.6纳米的金纳米颗粒与光合蛋白静电耦合，在水溶液中形成稳定的混合纳米生物共轭物。蛋白质的Q波段吸收光谱与金颗粒的局域表面等离子体共振重叠。在可见光区域，数值模拟和归一化CD测量相结合表明，与游离蛋白相比，增强因子为3。这一观察揭示了三种效应。首先，蛋白质环境中电磁手性密度局部增加。其次，蛋白质的吸收增加。第三，等离子体诱导圆二色性。我们的结果定量地证明了近场超手性直接调节生物分子的光学活性。这些发现为手性光学纳米器件、生物传感平台和光驱动不对称光化学开辟了新途径。
英文摘要
Controlling chiral light-matter interactions with nanophotonics is a powerful strategy for amplifying molecular circular dichroism (CD) beyond its natural limits. Here, we present a plasmonic platform that uses superchiral near fields to amplify the optical activity of biological chromophores. Gold nanoparticles (3.6 nm in diameter) are electrostatically coupled with photosynthetic proteins which results in stable hybrid nanobioconjugates in aqueous solution. The Q-band absorption spectrum of the proteins overlaps with the localized surface plasmon resonance of the gold particles. In the visible region, a combination of numerical simulations and normalized CD measurements reveal an enhancement factor of 3 compared to free proteins. This observation reveals three effects. First, there is a local increase in electromagnetic chirality density in the protein environment. Second, there is an increase in the absorption of the proteins. Third, there is plasmon-induced circular dichroism. Our results quantitatively demonstrate that near-field super-chirality directly modulates biomolecular optical activity. These findings open new avenues for chiroptical nanodevices, biosensing platforms, and light-driven asymmetric photochemistry.
