arXivDaily arXiv每日学术速递 周一至周五更新
arXiv周末暂无论文更新,休息一下吧,周末愉快~~
arXiv 2602.09787eess.IVphysics.app-phphysics.bio-phphysics.optics
收藏

基于强度的组织图像分割:使用预训练ResNet-34编码器的U-Net网络:应用于穆勒显微镜

Intensity-based Segmentation of Tissue Images Using a U-Net with a Pretrained ResNet-34 Encoder: Application to Mueller Microscopy

Florida International University(佛罗里达国际大学);CNRS, École Polytechnique, IP Paris(法国国家科学研究中心,巴黎综合理工学院,巴黎文理研究大学)

Sooyong Chae, Dani Giammattei, Ajmal Ajmal, Junzhu Pei, Amanda Sanchez, Tananant Boonya-ananta, Andres Rodriguez, Tatiana Novikova, Jessica Ramella-Roman

AI总结:

本文提出了一种基于强度的U-Net网络,利用预训练ResNet-34编码器对组织图像进行分割,应用于穆勒显微镜,实现了高精度的自动分割。

摘要:

在穆勒显微镜中,手动标注薄组织切片图像仍是一个耗时的步骤,限制了其可扩展性。我们提出了一种新的自动化方法,仅使用穆勒矩阵的总强度M11元素作为输入,传递给具有预训练ResNet-34编码器的U-Net架构。该网络被训练以区分小鼠子宫颈切片图像的四个类别:背景、内部口、宫颈组织和阴道壁。仅使用70个宫颈组织切片,模型在保留的测试数据集上实现了89.71%的像素准确率和80.96%的平均组织Dice系数。从ImageNet迁移学习使得在典型的专用生物医学成像中,即使训练数据集较小,也能实现准确的分割。这种基于强度的框架需要最小的预处理,并且可以轻松扩展到其他成像模式和组织类型,且有公开可用的图形注释工具用于实际部署。

英文摘要:

Manual annotation of the images of thin tissue sections remains a time-consuming step in Mueller microscopy and limits its scalability. We present a novel automated approach using only the total intensity M11 element of the Mueller matrix as an input to a U-Net architecture with a pretrained ResNet-34 encoder. The network was trained to distinguish four classes in the images of murine uterine cervix sections: background, internal os, cervical tissue, and vaginal wall. With only 70 cervical tissue sections, the model achieved 89.71% pixel accuracy and 80.96% mean tissue Dice coefficient on the held-out test dataset. Transfer learning from ImageNet enables accurate segmentation despite limited size of training dataset typical of specialized biomedical imaging. This intensity-based framework requires minimal preprocessing and is readily extensible to other imaging modalities and tissue types, with publicly available graphical annotation tools for practical deployment.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑