arXivDaily arXiv每日学术速递 周一至周五更新
arXiv周末暂无论文更新,休息一下吧,周末愉快~~
arXiv 2602.00561cs.AI
收藏

通过自适应流路由揭示脑网络中的潜在通信模式

Uncovering Latent Communication Patterns in Brain Networks via Adaptive Flow Routing

University of Virginia(弗吉尼亚大学)

Tianhao Huang, Guanghui Min, Zhenyu Lei, Aiying Zhang, Chen Chen

AI总结:

本文提出AFR-Net,通过神经通信动态视角融合SC和FC,揭示潜在神经通路,优于现有方法。

摘要:

解开宏观认知表型如何从微观神经元连接中产生仍然是神经科学的核心追求之一。为此,研究者通常利用结构性连接(SC)和功能连接(FC)的多模态信息来完成下游任务。最近的方法探索SC和FC之间复杂的耦合机制,试图在区域层面融合它们的表示。然而,缺乏基本神经科学见解,这些方法未能揭示这些连接体下神经区域之间的潜在相互作用,因此无法解释为什么SC和FC表现出耦合和异质性的动态状态。在本文中,我们通过神经通信动态的视角进行多模态融合,并提出自适应流路由网络(AFR-Net),这是一个具有物理信息的框架,用于建模结构性约束(SC)如何产生功能性通信模式(FC),从而能够解释关键神经通路。大量实验表明,AFR-Net显著优于最先进的基线方法。代码可在https://anonymous.4open.science/r/DIAL-F0D1获取。

英文摘要:

Unraveling how macroscopic cognitive phenotypes emerge from microscopic neuronal connectivity remains one of the core pursuits of neuroscience. To this end, researchers typically leverage multi-modal information from structural connectivity (SC) and functional connectivity (FC) to complete downstream tasks. Recent methodologies explore the intricate coupling mechanisms between SC and FC, attempting to fuse their representations at the regional level. However, lacking fundamental neuroscientific insight, these approaches fail to uncover the latent interactions between neural regions underlying these connectomes, and thus cannot explain why SC and FC exhibit dynamic states of both coupling and heterogeneity. In this paper, we formulate multi-modal fusion through the lens of neural communication dynamics and propose the Adaptive Flow Routing Network (AFR-Net), a physics-informed framework that models how structural constraints (SC) give rise to functional communication patterns (FC), enabling interpretable discovery of critical neural pathways. Extensive experiments demonstrate that AFR-Net significantly outperforms state-of-the-art baselines. The code is available at https://anonymous.4open.science/r/DIAL-F0D1.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

↑