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arXiv 2511.20145cs.CV
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用于自动化3D PET/CT报告生成的视觉-语言模型

Vision-Language Models for Automated 3D PET/CT Report Generation

Institute of Medical Technology and National Biomedical Imaging Center, Peking University(北京大学医学技术研究院和国家生物医学成像中心);Peking University People’s Hospital(北京大学人民医院);Peking University Third Hospital(北京大学第三医院);DAMO Academy, Alibaba Group(阿里巴巴集团达摩院);The Affiliated Hospital of Qingdao University(青岛大学附属医院);The First Affiliated Hospital of Henan Medical University(河南医科大学第一附属医院);Jiujiang City Key Laboratory of Cell Therapy, Jiu Jiang NO.1 People’s Hospital(九江市细胞治疗重点实验室,九江市第一人民医院)

Wenpei Jiao, Kun Shang, Hui Li, Ke Yan, Jiajin Zhang, Guangjie Yang, Lijuan Guo, Yan Wan, Xing Yang, Dakai Jin, Zhaoheng Xie

AI总结:

本文提出PETRG-3D模型,通过3D双分支框架和风格适应提示,提升PET/CT报告生成的自动化水平,实验显示其在自然语言和临床指标上均优于现有方法。

摘要:

正电子发射断层扫描/计算机断层扫描(PET/CT)在肿瘤学中至关重要,但扫描仪的快速扩张已超过了受过训练的专业人员的供应,因此自动化PET/CT报告生成(PETRG)在减少临床工作量方面变得越来越重要。与结构性成像(如X射线、CT和MRI)相比,功能性PET提出了不同的挑战:代谢模式随示踪剂生理学变化,需要整个身体3D上下文信息而不是局部区域解释。为了推进PETRG,我们提出了PETRG-3D,一种端到端的3D双分支框架,该框架分别编码PET和CT体积,并结合风格适应提示以缓解不同医院报告实践的差异。我们构建了PETRG-Lym,一个由四个医院收集的多中心淋巴瘤数据集(824份报告,245,509对PET/CT切片),并构建了AutoPET-RG-Lym,一个公开可访问的PETRG基准,来源于开放影像数据,但配备了新的专家编写、临床验证的报告(135例)。为了评估临床效用,我们引入了PETRG-Score,一个专门针对淋巴瘤的评估协议,联合测量在经过整理的解剖区域中的代谢和结构性发现。实验显示,PETRG-3D在自然语言指标(如ROUGE-L提高31.49%)和临床有效性指标(如PET-All提高8.18%)上均显著优于现有方法,突显了体积分支模态建模和风格感知提示的好处。总体而言,这项工作为未来专门针对PET/CT的模型奠定了基础,强调疾病感知推理和临床可靠评估。代码、模型和AutoPET-RG-Lym将被发布。

英文摘要:

Positron emission tomography/computed tomography (PET/CT) is essential in oncology, yet the rapid expansion of scanners has outpaced the availability of trained specialists, making automated PET/CT report generation (PETRG) increasingly important for reducing clinical workload. Compared with structural imaging (e.g., X-ray, CT, and MRI), functional PET poses distinct challenges: metabolic patterns vary with tracer physiology, and whole-body 3D contextual information is required rather than local-region interpretation. To advance PETRG, we propose PETRG-3D, an end-to-end 3D dual-branch framework that separately encodes PET and CT volumes and incorporates style-adaptive prompts to mitigate inter-hospital variability in reporting practices. We construct PETRG-Lym, a multi-center lymphoma dataset collected from four hospitals (824 reports w/ 245,509 paired PET/CT slices), and construct AutoPET-RG-Lym, a publicly accessible PETRG benchmark derived from open imaging data but equipped with new expert-written, clinically validated reports (135 cases). To assess clinical utility, we introduce PETRG-Score, a lymphoma-specific evaluation protocol that jointly measures metabolic and structural findings across curated anatomical regions. Experiments show that PETRG-3D substantially outperforms existing methods on both natural language metrics (e.g., +31.49\% ROUGE-L) and clinical efficacy metrics (e.g., +8.18\% PET-All), highlighting the benefits of volumetric dual-modality modeling and style-aware prompting. Overall, this work establishes a foundation for future PET/CT-specific models emphasizing disease-aware reasoning and clinically reliable evaluation. Codes, models, and AutoPET-RG-Lym will be released.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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