看得更清楚,治疗更智能:长轴视野PET-CT在治疗诊断学发展中的作用
Seeing More, Treating Smarter: Role of Long-Axial Field-of-View PET-CT in The Evolution of Theranostics
AI总结:
长轴视野PET-CT通过提升灵敏度和覆盖范围,推动治疗诊断学的个性化发展。
摘要:
长轴视野PET/CT有潜力通过使多参数全身体检和预测剂量学在临床上更可行,重新定义分子成像在治疗诊断学中的作用。与传统PET系统相比,长轴视野扫描仪在灵敏度和覆盖范围上有了显著提升,允许动态采集、延迟成像和双示踪协议在临床可行的工作流程中进行。这些进展提供了用于基于生理的药代动力学(PBPK)建模和创建治疗诊断学数字双胞胎所需的定量数据,支持放射性药物治疗的真正个性化。
英文摘要:
Long-axial field-of-view (LAFOV) PET/CT has the potential to redefine the role of molecular imaging in theranostics by making multiparametric whole-body (MPWB) imaging and predictive dosimetry more clinically feasible. Compared to conventional PET systems, LAFOV scanners provide dramatic gains in sensitivity and coverage, allowing dynamic acquisitions, delayed imaging, and dual-tracer protocols within clinically feasible workflows. These advances supply the quantitative data required for physiologically based pharmacokinetic (PBPK) modeling and the creation of theranostic digital twins, supporting true personalization of radiopharmaceutical therapy.
机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。