Fully supervised deep models have shown promising performance for many medical segmentation tasks. Still, the deployment of these tools in clinics is limited by the very timeconsuming collection of manually expert-annotated data. Moreover, most of the state-ofthe-art models have been trained and validated on moderately homogeneous datasets. It is known that deep learning methods are often greatly degraded by domain or label shifts and are yet to be built in such a way as to be robust to unseen data or label distributions. In the clinical setting, this problematic is particularly relevant as the deployment institutions may have different scanners or acquisition protocols than those from which the data has been collected to train the model. In this work, we propose to address these two challenges on the detection of clinically significant prostate cancer (csPCa) from bi-parametric MRI. We evaluate the method proposed by (Kervadec et al., 2018), which introduces a size constaint loss to produce fine semantic cancer lesions segmentations from weak circle scribbles annotations. Performance of the model is based on two public (PI-CAI and Prostate158) and one private databases. First, we show that the model achieves on-par performance with strong fully supervised baseline models, both on in-distribution validation data and unseen test images. Second, we observe a performance decrease for both fully supervised and weakly supervised models when tested on unseen data domains. This confirms the crucial need for efficient domain adaptation methods if deep learning models are aimed to be deployed in a clinical environment. Finally, we show that ensemble predictions from multiple trainings increase generalization performance.
Ultra-Strong Gradient Diffusion MRI with Self-Supervised Learning for Prostate Cancer Characterization
University College London（伦敦大学学院）；Cardiff University（卡迪夫大学）；Siemens Healthcare Ltd（西门子医疗有限公司）；Siemens Healthcare GmbH（西门子医疗股份公司）；University Medical Center Utrecht（乌得勒支大学医学中心）
A Transfer Learning Approach for Automated Segmentation of Prostate Whole Gland and Transition Zone in Diffusion Weighted MRI
University of Toronto（多伦多大学）；Lunenfeld-Tanenbaum Research Institute, Sinai Health System（Sinai Health System 伦内菲尔德-塔嫩鲍姆研究所）；Brigham and Women’s Hospital（布莱根妇女医院）；The Hospital for Sick Children（SickKids 医院）
Multiparametric Deep Learning Tissue Signatures for a Radiological Biomarker of Breast Cancer: Preliminary Results
The Johns Hopkins University School of Medicine（约翰霍普金斯大学医学院）；Sidney Kimmel Comprehensive Cancer Center（西德尼·基梅尔综合癌症中心）；The Johns Hopkins University（约翰霍普金斯大学）；University of Kentucky（肯塔基大学）；University of Wisconsin School of Medicine and Public Health（威斯康星大学医学与公共卫生学院）
Repeatability of Multiparametric Prostate MRI Radiomics Features
Brigham and Women's Hospital（布莱根妇女医院）；Harvard Medical School（哈佛医学院）；Netherlands Cancer Institute（荷兰癌症研究所）；Maastricht University（马斯特里赫特大学）；Massachusetts General Hospital（麻省总医院）；Isomics, Inc.（Isomics公司）；Dana-Farber Cancer Institute（丹娜-法伯癌症研究所）
Mask-guided Data Augmentation for Multiparametric MRI Generation with a Rare Hepatocellular Carcinoma
Universidad Industrial de Santander（桑坦德工业大学）；University of Toulouse（图卢兹大学）；Université Paul Sabatier Toulouse 3（图卢兹第三大学（保罗·萨巴蒂埃大学））；Bicêtre University Hospital（比塞特尔大学医院）；Assistance publique des hôpitaux de Paris（巴黎公共援助医院）；Université Claude Bernard Lyon 1（里昂第一大学（克洛德·贝尔纳里昂第一大学））
FastMRI Prostate: A Publicly Available, Biparametric MRI Dataset to Advance Machine Learning for Prostate Cancer Imaging
New York University Grossman School of Medicine（纽约大学格罗斯曼医学院）；Siemens Medical Solutions USA（美国西门子医疗解决方案公司）；Courant Institute of Mathematical Sciences, New York University（纽约大学柯朗数学科学研究所）
ProstAttention-Net: A deep attention model for prostate cancer segmentation by aggressiveness in MRI scans
Univ Lyon（里昂大学）；CNRS（法国国家科学研究中心）；Inserm（法国国家健康与医学研究院）；INSA Lyon（里昂国立应用科学学院）；UCBL（里昂第一大学）；CREATIS（里昂影像与信息处理研究中心）；Hospices Civils de Lyon（里昂民用医院集团）；Hôpital Edouard Herriot（爱德华·埃里奥医院）；University of Sherbrooke（舍布鲁克大学）
Prostate Lesion Estimation using Prostate Masks from Biparametric MRI
Istanbul Technical University（伊斯坦布尔理工大学）；Acibadem Mehmet Ali Aydinlar University School of Medicine（阿吉巴德姆·穆罕默德·阿里·艾丁拉尔大学医学院）；Bahcesehir University（巴耶塞特大学）
Predicted disease compositions of human gliomas estimated from multiparametric MRI can predict endothelial proliferation, tumor grade, and overall survival
Indiana University School of Medicine（印第安纳大学医学院）；Purdue University（普渡大学）；Dayton Children’s Hospital（代顿儿童医院）
Image quality assessment by overlapping task-specific and task-agnostic measures: application to prostate multiparametric MR images for cancer segmentation
University College London（伦敦大学学院）；City University of Hong Kong（香港城市大学）；InstaDeep（InstaDeep公司）；University College London Hospital NHS Foundation Trust（伦敦大学学院医院国民保健服务基金会信托）
Universal Lymph Node Detection in Multiparametric MRI with Selective Augmentation
National Institutes of Health（美国国立卫生研究院）；National Library of Medicine（美国国家医学图书馆）；National Center for Biotechnology Information（国家生物技术信息中心）；Clinical Center（临床中心）；Radiology and Imaging Sciences（放射学与影像科学科）
CAT-Net: A Cross-Slice Attention Transformer Model for Prostate Zonal Segmentation in MRI
University of California, Los Angeles (UCLA)（加利福尼亚大学洛杉矶分校）；The First Affiliated Hospital of China Medical University（中国医科大学附属第一医院）；VoxelCloud, Inc.（体素云公司）
MS-Net: Multi-Site Network for Improving Prostate Segmentation with Heterogeneous MRI Data
The Chinese University of Hong Kong（香港中文大学）；Stanford University（斯坦福大学）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Non-Invasive Detection of PROState Cancer with Novel Time-Dependent Diffusion MRI and AI-Enhanced Quantitative Radiological Interpretation: PROS-TD-AI
University of Chile（智利大学）；Clínica Dávila（达维拉诊所）；Zhejiang University（浙江大学）；Hospital Clinic, Universitat de Barcelona（巴塞罗那大学医院诊所）；San Sebastián University（圣塞巴斯蒂安大学）
Diffusion MRI preprocessing affects ADC estimation and automatic PI-RADS v2.1 classification in bi-parametric prostate MRI
Center for Image Sciences, University Medical Center Utrecht（乌得勒支大学医学中心影像科学中心）；Department of Radiotherapy, University Medical Center Utrecht（乌得勒支大学医学中心放射治疗科）；Cerebriu（Cerebriu公司）；Department of Diagnostic Radiology, Copenhagen University Hospital Rigshospitalet（哥本哈根大学医院 Rigshospitalet 诊断放射科）；Department of Diagnostic Radiology, Copenhagen University Hospital Herlev and Gentofte（哥本哈根大学医院海尔鲁夫与根措夫特医院诊断放射科）
A cross-modal generative model for incomplete and degraded prostate MRI with multicentre clinical validation
College of Computing and Data Science, Nanyang Technological University（南洋理工大学计算与数据科学学院）；School of Computer Science and Technology, Tongji University（同济大学计算机科学与技术学院）；Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院附属仁济医院）；National University of Singapore（新加坡国立大学）；Shanghai East Hospital, Tongji University School of Medicine（同济大学医学院附属东方医院）；McWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston (UTHealth Houston)（德克萨斯大学休斯顿健康科学中心麦克威廉姆斯生物信息学院）；School of Transportation, Southeast University（东南大学交通学院）；Ningbo Hangzhou Bay Hospital（宁波杭州湾医院）；Changhai Hospital, Naval Medical University（海军军医大学长海医院）
DCE-FORMER: A Transformer-based Model With Mutual Information And Frequency-based Loss Functions For Early And Late Response Prediction In Prostate DCE-MRI
Fully automated quantification of in vivo viscoelasticity of prostate zones using magnetic resonance elastography with Dense U-net segmentation
Charité – Universitätsmedizin Berlin（柏林夏里特医学院）；Berlin Institute of Health at Charité – Universitätsmedizin Berlin（柏林夏里特医学院柏林健康研究所）；DKTK (German Cancer Consortium)（德国癌症联盟（DKTK））
