arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2409.04486physics.med-phcond-mat.mtrl-sci
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氧化锌纳米颗粒在糖尿病治疗中的现状与未来展望

The Current and Future Perspectives of Zinc Oxide Nanoparticles in the Treatment of Diabetes Mellitus

Iqra Yousaf

AI总结:

本文综述ZnO NPs的化学与绿色合成、表征技术及其抗菌、抗炎和抗糖尿病活性,指出其在血糖调控中的潜力与毒性研究需求。

摘要:

本综述探讨了氧化锌纳米颗粒(ZnO NPs)在糖尿病治疗中的合成、表征及治疗应用。研究深入分析了化学合成与绿色合成两种方法,并比较了它们对纳米颗粒性质的影响。XRD、FTIR、UV-Vis光谱和SEM等关键表征技术证实了纳米颗粒的晶体结构、光学性质和形貌。ZnO NPs表现出显著的生物活性,包括抗菌、抗炎和抗糖尿病作用。这些纳米颗粒在改善血糖调节、增强胰岛素敏感性以及促进细胞葡萄糖摄取方面展现出潜力。尽管具有上述益处,ZnO NPs的潜在毒性和长期影响仍需进一步研究。未来研究应聚焦于优化合成方法并开展全面研究,以充分发挥ZnO NPs在糖尿病管理及其他生物医学应用中的潜力。

英文摘要:

This review explores the synthesis, characterization, and therapeutic applications of zinc oxide nanoparticles (ZnO NPs) in the treatment of diabetes mellitus. The study delves into both chemical and green synthesis methods, comparing their impacts on nanoparticle properties. Key characterization techniques such as XRD, FTIR, UV-Vis spectroscopy, and SEM confirm the crystalline structure, optical properties, and morphology of the nanoparticles. ZnO NPs demonstrate significant biological activities, including antibacterial, anti-inflammatory, and antidiabetic effects. These nanoparticles show promise in improving glucose regulation, enhancing insulin sensitivity, and boosting glucose uptake in cells. Despite these benefits, the potential toxicity and long-term effects of ZnO NPs warrant further investigation. Future research should focus on optimizing synthesis methods and conducting comprehensive studies to fully exploit ZnO NPs' potential in diabetes management and other biomedical applications.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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