用于生物粒子监测的圆偏振光散射退偏振图
Depolarization diagrams for circularly polarized light scattering for biological particle monitoring
AI总结：
本文利用Monte Carlo模拟研究了圆偏振光退偏振强度与粒子尺寸和波长的相关性，生成了退偏振图，为血细胞监测、早期胚胎发生及抗原-抗体相互作用等生物粒子监测方法提供了可行性依据。
摘要：
意义：混浊介质中散射引起的圆偏振光退偏振揭示了分散粒子的结构信息，如其大小、密度和分布，这对于研究生物组织状态很有用。然而，退偏振强度与组织参数之间的相关性尚不明确。目标：我们旨在研究退偏振强度与粒子大小和波长的一般相关性，生成退偏振图。方法：使用Monte Carlo模拟方法，在单次和多次散射下检验了退偏振强度与尺寸参数之间的相关性。扩展波长宽度使我们能够获得作为波长和粒子直径函数的反射和透射几何的退偏振分布图。结果：圆偏振光在针对其波长的各种特定尺寸粒子的单次散射中遭受强烈退偏振，这在多次散射区域变得更加明显。结论：获得了以粒子大小和波长为自变量的退偏振图，这对于研究各种粒子监测方法的可行性特别有帮助。基于所获得的图，提出了几种应用，包括血细胞监测、早期胚胎发生和抗原-抗体相互作用。
英文摘要：
Significance: The depolarization of circularly polarized light caused by scattering in turbid media reveals structural information about the dispersed particles, such as their size, density, and distribution, which is useful for investigating the state of biological tissue. However, the correlation between depolarization strength and tissue parameters is unclear. Aim: We aimed to examine the generalized correlations of depolarization strength with the particle size and wavelength, yielding depolarization diagrams. Approach: The correlation between depolarization intensity and size parameter were examined for single and multiple scattering using the Monte Carlo simulation method. Expanding the wavelength width allows us to obtain depolarization distribution diagrams as functions of wavelength and particle diameter for reflection and transparent geometries. Results: Circularly polarized light suffers intensive depolarization in a single scattering against particles of various specific sizes for its wavelength, which becomes more noticeable in the multiple scattering regime. Conclusions: The depolarization diagrams with particle size and wavelength as independent variables were obtained, which are particularly helpful for investigating the feasibility of various particle-monitoring methods. Based on the obtained diagrams, several applications have been proposed, including blood cell monitoring, early embryogenesis, and antigen-antibody interactions.
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