Cancer is one of the diseases that kill the most women in the world, with breast cancer being responsible for the highest number of cancer cases and consequently deaths. However, it can be prevented by early detection and, consequently, early treatment. Any development for detection or perdition this kind of cancer is important for a better healthy life. Many studies focus on a model with high accuracy in cancer prediction, but sometimes accuracy alone may not always be a reliable metric. This study implies an investigative approach to studying the performance of different machine learning algorithms based on boosting to predict breast cancer focusing on the recall metric. Boosting machine learning algorithms has been proven to be an effective tool for detecting medical diseases. The dataset of the University of California, Irvine (UCI) repository has been utilized to train and test the model classifier that contains their attributes. The main objective of this study is to use state-of-the-art boosting algorithms such as AdaBoost, XGBoost, CatBoost and LightGBM to predict and diagnose breast cancer and to find the most effective metric regarding recall, ROC-AUC, and confusion matrix. Furthermore, our study is the first to use these four boosting algorithms with Optuna, a library for hyperparameter optimization, and the SHAP method to improve the interpretability of our model, which can be used as a support to identify and predict breast cancer. We were able to improve AUC or recall for all the models and reduce the False Negative for AdaBoost and LigthGBM the final AUC were more than 99.41\% for all models.
One-dimensional convolutional neural network model for breast cancer subtypes classification and biochemical content evaluation using micro-FTIR hyperspectral images
Energy and Nuclear Research Institute, University of São Paulo（圣保罗大学能源与核研究学院）；Radiopharmacy Center, Energy and Nuclear Research Institute, University of São Paulo（圣保罗大学能源与核研究学院放射药学中心）
Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world adoption in high-stakes decision-making. In this paper, we propose an interactive system to take advantage of state-of-the-art interpretability techniques to assist radiologists with breast cancer screening. Our system integrates a deep learning model into the radiologists' workflow and provides novel interactions to promote understanding of the model's decisio…
University of Minnesota（明尼苏达大学）；University of Cincinnati（辛辛那提大学）
Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although remarkable in performance, are black-box systems that provide minimal insight into the inner logic behind their predictions. This is a major drawback as the explainability of prediction is vital for applications such as cancer diagnosis. In this paper, we address this issue by proposing an explainable machine learning pipeline for breast cancer diagnosis base…
This paper introduces X-SHAP, a model-agnostic method that assesses multiplicative contributions of variables for both local and global predictions. This method theoretically and operationally extends the so-called additive SHAP approach. It proves useful underlying multiplicative interactions of factors, typically arising in sectors where Generalized Linear Models are traditionally used, such as in insurance or biology. We test the method on various datasets and propose a set of techniques based on individual X-SHAP contributions to build aggregated multiplicative contributions and to capture…
State-of-the-art deep neural networks (DNNs) are highly effective in solving many complex real-world problems. However, these models are vulnerable to adversarial perturbation attacks, and despite the plethora of research in this domain, to this day, adversaries still have the upper hand in the cat and mouse game of adversarial example generation methods vs. detection and prevention methods. In this research, we present a novel detection method that uses Shapley Additive Explanations (SHAP) values computed for the internal layers of a DNN classifier to discriminate between normal and adversari…
Peking University（北京大学）；Virginia Military Institute（弗吉尼亚军事学院）
In this paper, we present an uncertainty-aware INVASE to quantify predictive confidence of healthcare problem. By introducing learnable Gaussian distributions, we lever-age their variances to measure the degree of uncertainty. Based on the vanilla INVASE, two additional modules are proposed, i.e., an uncertainty quantification module in the predictor, and a reward shaping module in the selector. We conduct extensive experiments on UCI-WDBC dataset. Notably, our method eliminates almost all predictive bias with only about 20% queries, while the uncertainty-agnostic counterpart requires nearly 1…
Utilizing Large Language Models for Machine Learning Explainability
Centre for Research \& Technology, Hellas School of Architecture Technology；Engineering, University of Brighton, BN2 4GJ, United Kingdom University of Nicosia, 2417 Cyprus
Radiological and Biological Dictionary of Radiomics Features: Addressing Understandable AI Issues in Personalized Breast Cancer; Dictionary Version BM1.0
Hamadan University of Medical Sciences（哈马丹医科大学）；Amirkabir University of Technology（阿米尔卡比尔理工大学）；Motamed Cancer Institute（莫塔梅德癌症研究所）；University of British Columbia（不列颠哥伦比亚大学）；BC Cancer Research Institute（不列颠哥伦比亚癌症研究所）；Technological Virtual Collaboration (TECVICO Corp.)（技术虚拟协作公司）
Deep Learning: a Heuristic Three-stage Mechanism for Grid Searches to Optimize the Future Risk Prediction of Breast Cancer Metastasis Using EHR-based Clinical Data
University of Pittsburgh（匹兹堡大学）；Pittsburgh VA Health System（匹兹堡退伍军人健康系统）；University of Pittsburgh School of Medicine（匹兹堡大学医学院）；UPMC Hillman Cancer Center（UPMC希尔曼癌症中心）
In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer detection in breast ultrasound images. The proposed approach incorporates tasks for explaining and classifying breast tumors, by learning feature representations relevant to clinical diagnosis. Explanations of the predictions (benign or malignant) are provided in terms of morphological features that are used by clinicians for diagnosis and reporting in medical pra…
Breast Cancer Diagnosis: A Comprehensive Exploration of Explainable Artificial Intelligence (XAI) Techniques
Canadian Institute of Cybersecurity (CIC)（加拿大网络安全研究所）；University of New Brunswick（新不伦瑞克大学）；Dipartimento di Informatica, Università di Verona（威尼斯大学信息学院）；Università di Verona（威尼斯大学）；Department of Computer Science, School of Mathematics and Computer Science, Institute of Business Administration（计算机科学系，数学与计算机科学学院，商学院）；LIRIS, CNRS, Université Claude Bernard Lyon 1（LIRIS，国家科学研究中心，克莱尔伯恩大学 Lyon 1 分校）；LHC, UMR5516, Université de Saint-Etienne（LHC，UMR5516，圣艾蒂安大学）
Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide adoption in clinical practice. To address the need for AI guided breast cancer diagnosis, interpretability methods can be utilized. In this study, we used AI methods, i.e., Random Forests (RF), Neural Networks (NN) and Ensembles of Neural Networks (ENN), towards this goal and explained and optimized their performance through interpretability techniques, such as…
Explainability for Fault Detection System in Chemical Processes
Department of Information and Electronic Engineering, International Hellenic University, Greece（信息与电子工程系，国际希腊大学）；Department of Industrial Engineering and Management, International Hellenic University, Greece（工业工程与管理系，国际希腊大学）；Energy Resources Institute, Centre for Research and Technology Hellas, Greece（能源资源研究所，希腊研究中心与技术中心）
International initiatives such as METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) have collected several multigenomic and clinical data sets to identify the undergoing molecular processes taking place throughout the evolution of various cancers. Numerous Machine Learning and statistical models have been designed and trained to analyze these types of data independently, however, the integration of such differently shaped and sourced information streams has not been extensively studied. To better integrate these data sets and generate meaningful representations that can u…
University of Waterloo（滑铁卢大学）；Waterloo Artificial Intelligence Institute（滑铁卢人工智能研究所）；DarwinAI Corp.（达尔文人工智能公司）
There has been a significant surge of interest recently around the concept of explainable artificial intelligence (XAI), where the goal is to produce an interpretation for a decision made by a machine learning algorithm. Of particular interest is the interpretation of how deep neural networks make decisions, given the complexity and `black box' nature of such networks. Given the infancy of the field, there has been very limited exploration into the assessment of the performance of explainability methods, with most evaluations centered around subjective visual interpretation of the produced int…
Predictive Modeling for Breast Cancer Classification in the Context of Bangladeshi Patients: A Supervised Machine Learning Approach with Explainable AI
Southern Illinois University Carbondale（南伊利诺伊大学卡本代尔分校）；Daffodil International University（达夫迪尔国际大学）；King Saud University（沙特国王大学）；Bahir Dar University（巴赫达尔大学）；Laval University（拉瓦尔大学）；Ibn Zohr University（伊本·佐赫尔大学）
Beijing Institute of Technology（北京理工大学）；Université 8 Mai 1945 Guelma（盖勒马8 Mai 1945大学）；National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College（中国医学科学院北京协和医学院肿瘤医院国家癌症中心国家肿瘤临床研究中心）
Mammography remains the most prevalent imaging tool for early breast cancer screening. The language used to describe abnormalities in mammographic reports is based on the breast Imaging Reporting and Data System (BI-RADS). Assigning a correct BI-RADS category to each examined mammogram is a strenuous and challenging task for even experts. This paper proposes a new and effective computer-aided diagnosis (CAD) system to classify mammographic masses into four assessment categories in BI-RADS. The mass regions are first enhanced by means of histogram equalization and then semiautomatically segment…
Unifying Interpretability and Explainability for Alzheimer's Disease Progression Prediction
Kansas State University（堪萨斯州立大学）；Carnegie Mellon University（卡内基梅隆大学）；University of Kansas Medical Center（堪萨斯大学医学中心）；Alzheimer’s Disease Research Center（阿尔茨海默病研究中心）
