This article investigates deep learning methodologies for single-modality clinical data analysis, as a crucial precursor to multi-modal medical research. Building on Guo JingYuan's work, the study refines clinical data processing through Compact Convolutional Transformer (CCT), Patch Up, and the innovative CamCenterLoss technique, establishing a foundation for future multimodal investigations. The proposed methodology demonstrates improved prediction accuracy and at tentiveness to critically ill patients compared to Guo JingYuan's ResNet and StageNet approaches. Novelty that using image-pretrained vision transformer backbone to perform transfer learning time-series clinical data.The study highlights the potential of CCT, Patch Up, and novel CamCenterLoss in processing single modality clinical data within deep learning frameworks, paving the way for future multimodal medical research and promoting precision and personalized healthcare
Snap Research, Snap. Inc.（Snap研究院，Snap公司）；University of Southern California（南加州大学）
Combining complementary information from multiple modalities is intuitively appealing for improving the performance of learning-based approaches. However, it is challenging to fully leverage different modalities due to practical challenges such as varying levels of noise and conflicts between modalities. Existing methods do not adopt a joint approach to capturing synergies between the modalities while simultaneously filtering noise and resolving conflicts on a per sample basis. In this work we propose a novel deep neural network based technique that multiplicatively combines information from d…
Deep Insights into Cognitive Decline: A Survey of Leveraging Non-Intrusive Modalities with Deep Learning Techniques
Dept. of Computer Science and Technology（计算机科学与技术系）；University of Alicante（阿尔瓦登特大学）；Unit of Clinical Nursing Research（临床护理研究单位）；Faculty of Health Sciences（健康科学学院）
School of Mechano-Electronic Engineering, Xidian University（西安电子科技大学机电工程学院）；Computer Science Department, Aberystwyth University（阿伯里斯特威斯大学计算机科学系）；School of Automation, Northwestern Polytechnical University（西北工业大学自动化学院）；Deepwise AI Lab（深睿人工智能实验室）
Recent advances in machine learning and prevalence of digital medical images have opened up an opportunity to address the challenging brain tumor segmentation (BTS) task by using deep convolutional neural networks. However, different from the RGB image data that are very widespread, the medical image data used in brain tumor segmentation are relatively scarce in terms of the data scale but contain the richer information in terms of the modality property. To this end, this paper proposes a novel cross-modality deep feature learning framework to segment brain tumors from the multi-modality MRI d…
Deep learning models, such as the fully convolutional network (FCN), have been widely used in 3D biomedical segmentation and achieved state-of-the-art performance. Multiple modalities are often used for disease diagnosis and quantification. Two approaches are widely used in the literature to fuse multiple modalities in the segmentation networks: early-fusion (which stacks multiple modalities as different input channels) and late-fusion (which fuses the segmentation results from different modalities at the very end). These fusion methods easily suffer from the cross-modal interference caused by…
Huazhong University of Science and Technology（华中科技大学）；Guizhou Normal University（贵州师范大学）；Hubei University（湖北大学）
Mapping X-ray images, radiology reports, and other medical data as binary codes in the common space, which can assist clinicians to retrieve pathology-related data from heterogeneous modalities (i.e., hashing-based cross-modal medical data retrieval), provides a new view to promot computeraided diagnosis. Nevertheless, there remains a barrier to boost medical retrieval accuracy: how to reveal the ambiguous semantics of medical data without the distraction of superfluous information. To circumvent this drawback, we propose Deep Supervised Information Bottleneck Hashing (DSIBH), which effectivel…
Guangdong General Hospital（广东省人民医院）；Guangdong Academy of Medical Sciences（广东省医学科学院）；Henan Provincial People’s Hospital（河南省人民医院）；Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Multi-modal magnetic resonance imaging (MRI) is essential in clinics for comprehensive diagnosis and surgical planning. Nevertheless, the segmentation of multi-modal MR images tends to be time-consuming and challenging. Convolutional neural network (CNN)-based multi-modal MR image analysis commonly proceeds with multiple down-sampling streams fused at one or several layers. Although inspiring performance has been achieved, the feature fusion is usually conducted through simple summation or concatenation without optimization. In this work, we propose a supervised image fusion method to selectiv…
National Center for Artificial Intelligence (NCAI), SDAIA（沙特数据与人工智能局国家人工智能中心（NCAI））；The Chinese University of Hong Kong (Shenzhen)（香港中文大学（深圳））；Shenzhen Research Institute of Big Data（深圳大数据研究院）；Shenzhen Institute of Artificial Intelligence and Robotics for Society（深圳人工智能与机器人研究院）；Institute of High Performance Computing, Agency for Science, Technology and Research（科技研究局高性能计算研究所）
Magnetic resonance (MR) imaging produces detailed images of organs and tissues with better contrast, but it suffers from a long acquisition time, which makes the image quality vulnerable to say motion artifacts. Recently, many approaches have been developed to reconstruct full-sampled images from partially observed measurements to accelerate MR imaging. However, most approaches focused on reconstruction over a single modality, neglecting the discovery of correlation knowledge between the different modalities. Here we propose a Multi-modal Aggregation network for mR Image recOnstruction with au…
Multi-modal data generation with a deep metric variational autoencoder
Technical University of Denmark（丹麦技术大学）；Interacoustics Research Unit（国际听力研究单元）；Interacoustics A/S（国际听力公司）；Kamide ENT clinic（上田耳鼻咽喉科诊所）；Diatec Japan（迪亚泰克日本公司）
Deep Unfolding Network with Spatial Alignment for multi-modal MRI reconstruction
Shanghai University（上海大学）；School of Science, Shanghai University（上海大学理学院）；School of Communication and Information Engineering, Shanghai University（上海大学通信与信息工程学院）；Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University（上海大学上海应用数学与力学研究所）；School of Mechanics and Engineering Science, Shanghai University（上海大学力学与工程科学学院）
Muroran Institute of Technology（室兰工业大学）；Niigata University of Health and Welfare（新潟医疗福祉大学）
To promote the development of medical image segmentation technology, AMOS, a large-scale abdominal multi-organ dataset for versatile medical image segmentation, is provided and AMOS 2022 challenge is held by using the dataset. In this report, we present our solution for the AMOS 2022 challenge. We employ residual U-Net with deep super vision as our base model. The experimental results show that the mean scores of Dice similarity coefficient and normalized surface dice are 0.8504 and 0.8476 for CT only task and CT/MRI task, respectively.
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）；University of Chinese Academy of Sciences（中国科学院大学）；Peng Cheng Laboratory（鹏城实验室）；Guangdong Provincial People’s Hospital（广东省人民医院）；Guangdong Academy of Medical Sciences（广东省医学科学院）
Brain tumor segmentation based on multi-modal magnetic resonance imaging (MRI) plays a pivotal role in assisting brain cancer diagnosis, treatment, and postoperative evaluations. Despite the achieved inspiring performance by existing automatic segmentation methods, multi-modal MRI data are still unavailable in real-world clinical applications due to quite a few uncontrollable factors (e.g. different imaging protocols, data corruption, and patient condition limitations), which lead to a large performance drop during practical applications. In this work, we propose a Deeply supervIsed knowledGE …
Accurate cardiac computing, analysis and modeling from multi-modality images are important for the diagnosis and treatment of cardiac disease. Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is a promising technique to visualize and quantify myocardial infarction (MI) and atrial scars. Automating quantification of MI and atrial scars can be challenging due to the low image quality and complex enhancement patterns of LGE MRI. Moreover, compared with the other sequences LGE MRIs with gold standard labels are particularly limited, which represents another obstacle for developing …
We propose a novel deep multi-modality neural network for restoring very low bit rate videos of talking heads. Such video contents are very common in social media, teleconferencing, distance education, tele-medicine, etc., and often need to be transmitted with limited bandwidth. The proposed CNN method exploits the correlations among three modalities, video, audio and emotion state of the speaker, to remove the video compression artifacts caused by spatial down sampling and quantization. The deep learning approach turns out to be ideally suited for the video restoration task, as the complex no…
Indian Institute of Technology Bombay（印度理工学院孟买分校）；German Aerospace Center (DLR)（德国航空航天中心）
We address the problem of cross-modal information retrieval in the domain of remote sensing. In particular, we are interested in two application scenarios: i) cross-modal retrieval between panchromatic (PAN) and multi-spectral imagery, and ii) multi-label image retrieval between very high resolution (VHR) images and speech based label annotations. Notice that these multi-modal retrieval scenarios are more challenging than the traditional uni-modal retrieval approaches given the inherent differences in distributions between the modalities. However, with the growing availability of multi-source …
Sichuan University（四川大学）；Chengdu University of Information Technology（成都信息工程大学）
Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to obtain full-sequence MRI images of patients owing to limitations such as time consumption and high cost. The purpose of this work is to develop an algorithm for target MRI sequences prediction with high accuracy, and provide more information for clinical diagnosis. Methods: We propose a deep learning based multi-modal computing model for MRI synthesis with featur…
Université de Rouen Normandie（鲁昂诺曼底大学）；INSA Rouen（鲁昂应用科学学院）
Multi-modality is widely used in medical imaging, because it can provide multiinformation about a target (tumor, organ or tissue). Segmentation using multimodality consists of fusing multi-information to improve the segmentation. Recently, deep learning-based approaches have presented the state-of-the-art performance in image classification, segmentation, object detection and tracking tasks. Due to their self-learning and generalization ability over large amounts of data, deep learning recently has also gained great interest in multi-modal medical image segmentation. In this paper, we give an …
Deep learning-based image processing is capable of creating highly appealing results. However, it is still widely considered as a "blackbox" transformation. In medical imaging, this lack of comprehensibility of the results is a sensitive issue. The integration of known operators into the deep learning environment has proven to be advantageous for the comprehensibility and reliability of the computations. Consequently, we propose the use of the locally linear guided filter in combination with a learned guidance map for general purpose medical image processing. The output images are only process…
INSA de Rouen（鲁昂国立应用科学学院）；Université de Rouen Normandie（鲁昂诺曼底大学）；Normandie Univ（诺曼底大学）；Henri Becquerel Cancer Center（亨利·贝克勒尔癌症中心）
Using multimodal Magnetic Resonance Imaging (MRI) is necessary for accurate brain tumor segmentation. The main problem is that not all types of MRIs are always available in clinical exams. Based on the fact that there is a strong correlation between MR modalities of the same patient, in this work, we propose a novel brain tumor segmentation network in the case of missing one or more modalities. The proposed network consists of three sub-networks: a feature-enhanced generator, a correlation constraint block and a segmentation network. The feature-enhanced generator utilizes the available modali…
Multi-atlas segmentation (MAS) is a promising framework for medical image segmentation. Generally, MAS methods register multiple atlases, i.e., medical images with corresponding labels, to a target image; and the transformed atlas labels can be combined to generate target segmentation via label fusion schemes. Many conventional MAS methods employed the atlases from the same modality as the target image. However, the number of atlases with the same modality may be limited or even missing in many clinical applications. Besides, conventional MAS methods suffer from the computational burden of reg…
Arguably the most common and salient object in daily video communications is the talking head, as encountered in social media, virtual classrooms, teleconferences, news broadcasting, talk shows, etc. When communication bandwidth is limited by network congestions or cost effectiveness, compression artifacts in talking head videos are inevitable. The resulting video quality degradation is highly visible and objectionable due to high acuity of human visual system to faces. To solve this problem, we develop a multi-modality deep convolutional neural network method for restoring face videos that ar…
Recent progress in automated PET/CT lesion segmentation using deep learning methods has demonstrated the feasibility of this task. However, tumor lesion detection and segmentation in whole-body PET/CT is still a chal-lenging task. To promote research on machine learning-based automated tumor lesion segmentation on whole-body FDG-PET/CT data, Automated Lesion Segmentation in Whole-Body FDG-PET/CT (autoPET) challenge is held, and a large, publicly available training dataset is provided. In this report, we present our solution to the autoPET challenge. We employ multi-modal residual U-Net with de…
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院）
Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and structural information from multi-modal neuroimages. In this work, a novel cross-modal transformer generative adversarial network(CT-GAN) is proposed to fuse functional information contained in resting-state functional magnetic resonance imaging (rs-fMRI) and structural information contained in Diffusion Tensor Imaging (DTI). The developed bi-attention mech…
In this work, we explore different approaches to combine modalities for the problem of automated age-suitability rating of movie trailers. First, we introduce a new dataset containing videos of movie trailers in English downloaded from IMDB and YouTube, along with their corresponding age-suitability rating labels. Secondly, we propose a multi-modal deep learning pipeline addressing the movie trailer age suitability rating problem. This is the first attempt to combine video, audio, and speech information for this problem, and our experimental results show that multi-modal approaches significant…
The Hermite-Gaussian (HG) modes make up a complete and orthonormal basis, which have been extensively used to describe optical fields. Here, we demonstrate, for the first time to our knowledge, deep learning-based modal decomposition (MD) of HG beams. This method offers a fast, economical and robust way to acquire both the power content and phase information through a single-shot beam intensity image, which will be beneficial for the beam shaping, beam quality assessment, studies of resonator perturbations, and other further research on the HG beams.
Friedrich-Alexander University（弗里德里希-亚历山大大学）；International Max Planck Research School Physics of Light (IMPRS-PL)（国际马克斯·普朗克光物理研究学院（IMPRS-PL））；MIT（麻省理工学院）
Fundus photography and Optical Coherence Tomography Angiography (OCT-A) are two commonly used modalities in ophthalmic imaging. With the development of deep learning algorithms, fundus image processing, especially retinal vessel segmentation, has been extensively studied. Built upon the known operator theory, interpretable deep network pipelines with well-defined modules have been constructed on fundus images. In this work, we firstly train a modularized network pipeline for the task of retinal vessel segmentation on the fundus database DRIVE. The pretrained preprocessing module from the pipel…
Duke University（杜克大学）；Duke Kunshan University（昆山杜克大学）；North Carolina State University（北卡罗来纳州立大学）
Purpose: To develop a neural ordinary differential equation (ODE) model for visualizing deep neural network (DNN) behavior during multi-parametric MRI (mp-MRI) based glioma segmentation as a method to enhance deep learning explainability. Methods: By hypothesizing that deep feature extraction can be modeled as a spatiotemporally continuous process, we designed a novel deep learning model, neural ODE, in which deep feature extraction was governed by an ODE without explicit expression. The dynamics of 1) MR images after interactions with DNN and 2) segmentation formation can be visualized after …
