Although sparse-view computed tomography (CT) has significantly reduced radiation dose, it also introduces severe artifacts which degrade the image quality. In recent years, deep learning-based methods for inverse problems have made remarkable progress and have become increasingly popular in CT reconstruction. However, most of these methods suffer several limitations: dependence on high-quality training data, weak interpretability, etc. In this study, we propose a fully unsupervised framework called Deep Radon Prior (DRP), inspired by Deep Image Prior (DIP), to address the aforementioned limitations. DRP introduces a neural network as an implicit prior into the iterative method, thereby realizing cross-domain gradient feedback. During the reconstruction process, the neural network is progressively optimized in multiple stages to narrow the solution space in radon domain for the under-constrained imaging protocol, and the convergence of the proposed method has been discussed in this work. Compared with the popular pre-trained method, the proposed framework requires no dataset and exhibits superior interpretability and generalization ability. The experimental results demonstrate that the proposed method can generate detailed images while effectively suppressing image artifacts.Meanwhile, DRP achieves comparable or better performance than the supervised methods.
Beijing University of Posts and Telecommunications（北京邮电大学）
Computed Tomography (CT) plays an essential role in clinical diagnosis. Due to the adverse effects of radiation on patients, the radiation dose is expected to be reduced as low as possible. Sparse sampling is an effective way, but it will lead to severe artifacts on the reconstructed CT image, thus sparse-view CT image reconstruction has been a prevailing and challenging research area. With the popularity of mobile devices, the requirements for lightweight and real-time networks are increasing rapidly. In this paper, we design a novel lightweight network called CAGAN, and propose a dual-domain…
What if deep neural networks can learn from sparsity-inducing priors? When the networks are designed by combining layer modules (CNN, RNN, etc), engineers less exploit the inductive bias, i.e., existing well-known rules or prior knowledge, other than annotated training data sets. We focus on employing sparsity-inducing priors in deep learning to encourage the network to concisely capture the nature of high-dimensional data in an unsupervised way. In order to use non-differentiable sparsity-inducing norms as loss functions, we plug their proximal mappings into the automatic differentiation fram…
The Computer-Assisted Diagnosis systems could save workloads and give objective diagnostic to ophthalmologists. At first, feature extraction is a fundamental step. One of these retinal features is the fovea. The fovea is a small fossa on the fundus. The main vessels diverge from the optic nerve head and follow a specific course that can be geometrically modeled as a parabola, with a common vertex inside the optic nerve head and the fovea located along the apex of this parabola curve. Therefore, based on this assumption, the main retinal blood vessels are segmented and fitted to a parabolic mod…
Unsupervised Self-Prior Embedding Neural Representation for Iterative Sparse-View CT Reconstruction
School of Information Science and Technology, ShanghaiTech University（上海科技大学信息科学与技术学院）；Lingang Laboratory（临港实验室）；University of Michigan（密歇根大学）；Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology（华中科技大学同济医学院附属同济医院）；School of Biomedical Engineering, Shanghai Jiao Tong University（上海交通大学生物医学工程学院）
In this paper, we propose a sinogram inpainting network (SIN) to solve limited-angle CT reconstruction problem, which is a very challenging ill-posed issue and of great interest for several clinical applications. A common approach to the problem is an iterative reconstruction algorithm with regularization term, which can suppress artifacts and improve image quality, but requires high computational cost. The starting point of this paper is the proof of inpainting function for limited-angle sinogram is continuous, which can be approached by neural networks in a data-driven method, granted by the…
University of Oulu（奥卢大学）；University College London（伦敦大学学院）
Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the computational complexity of the CT reconstruction, and bespoke reconstruction algorithms need fine-tuning to varying noise statistics. \rev{Especially if many projections are taken, a large amount of data has to be collected and stored. Sparse view CT is one solution for data reduction. However, these issues are especially exacerbated when sparse imaging scenar…
Shanghai Jiao Tong University（上海交通大学）；University of Sydney（悉尼大学）；Ruijin Hospital, Shanghai Jiao Tong University School of Medicine（上海交通大学医学院瑞金医院）
Motion estimation is a fundamental step in dynamic medical image processing for the assessment of target organ anatomy and function. However, existing image-based motion estimation methods, which optimize the motion field by evaluating the local image similarity, are prone to produce implausible estimation, especially in the presence of large motion. In this study, we provide a novel motion estimation framework of Dense-Sparse-Dense (DSD), which comprises two stages. In the first stage, we process the raw dense image to extract sparse landmarks to represent the target organ anatomical topology…
Many imaging technologies rely on tomographic reconstruction, which requires solving a multidimensional inverse problem given a finite number of projections. Backprojection is a popular class of algorithm for tomographic reconstruction, however it typically results in poor image reconstructions when the projection angles are sparse and/or if the sensors characteristics are not uniform. Several deep learning based algorithms have been developed to solve this inverse problem and reconstruct the image using a limited number of projections. However these algorithms typically require examples of th…
In this paper, we estimate perceived image quality using sparse representations obtained from generic image databases through an unsupervised learning approach. A color space transformation, a mean subtraction, and a whitening operation are used to enhance descriptiveness of images by reducing spatial redundancy; a linear decoder is used to obtain sparse representations; and a thresholding stage is used to formulate suppression mechanisms in a visual system. A linear decoder is trained with 7 GB worth of data, which corresponds to 100,000 8x8 image patches randomly obtained from nearly 1,000 i…
Beijing University of Posts and Telecommunications（北京邮电大学）
Low-dose Computed Tomography is a common issue in reality. Current reduction, sparse sampling and limited-view scanning can all cause it. Between them, limited-view CT is general in the industry due to inevitable mechanical and physical limitation. However, limited-view CT can cause serious imaging problem on account of its massive information loss. Thus, we should effectively utilize the scant prior information to perform completion. It is an undeniable fact that CT imaging slices are extremely dense, which leads to high continuity between successive images. We realized that fully exploit the…
Novel data acquisition schemes have been an emerging need for scanning microscopy based imaging techniques to reduce the time in data acquisition and to minimize probing radiation in sample exposure. Varies sparse sampling schemes have been studied and are ideally suited for such applications where the images can be reconstructed from a sparse set of measurements. Dynamic sparse sampling methods, particularly supervised learning based iterative sampling algorithms, have shown promising results for sampling pixel locations on the edges or boundaries during imaging. However, dynamic sampling for…
Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to addressing the challenges when reconstructing images with measurement undersampling or various types of noise. In this work, we propose a hybrid supervised-unsupervised learning framework for X-ray computed tomography (CT) image reconstruction. The proposed learning formulation leverages both sparsity or unsupervised learning-based priors and neural network recon…
Accurate land cover segmentation of spectral images is challenging and has drawn widespread attention in remote sensing due to its inherent complexity. Although significant efforts have been made for developing a variety of methods, most of them rely on supervised strategies. Subspace clustering methods, such as Sparse Subspace Clustering (SSC), have become a popular tool for unsupervised learning due to their high performance. However, the computational complexity of SSC methods prevents their use on large spectral remotely sensed datasets. Furthermore, since SSC ignores the spatial informati…
We present a rotation-equivariant unsupervised learning framework for the sparse deconvolution of non-negative scalar fields defined on the unit sphere. Spherical signals with multiple peaks naturally arise in Diffusion MRI (dMRI), where each voxel consists of one or more signal sources corresponding to anisotropic tissue structure such as white matter. Due to spatial and spectral partial voluming, clinically-feasible dMRI struggles to resolve crossing-fiber white matter configurations, leading to extensive development in spherical deconvolution methodology to recover underlying fiber directio…
CPSNet: Physics-Inspired Label-Free Deep Unfolding for Lung Ultrasound B-Line Detection
UCL Hawkes Institute, University College London（伦敦大学学院霍克斯研究所）；Visual Information Laboratory, University of Bristol（布里斯托大学视觉信息实验室）；School of Computer Science and Informatics, Cardiff University（卡迪夫大学计算机科学与信息学院）；Nephrology, Dialysis and Transplantation, Careggi University Hospital（卡尔加奇大学医院肾病、透析与移植科）
提出用于肺部超声图像分析的 CPSNet 无标签深度展开框架，将柯西近端分裂算法展开为网络架构，引入新损失函数，无监督训练，用于 B 线检测时比传统方法更具优势，能有效辅助临床诊断。
ETH Zurich（苏黎世联邦理工学院）；University Hospital Zurich（苏黎世大学医院）
The segmentation of the mitral valve annulus and leaflets specifies a crucial first step to establish a machine learning pipeline that can support physicians in performing multiple tasks, e.g.\ diagnosis of mitral valve diseases, surgical planning, and intraoperative procedures. Current methods for mitral valve segmentation on 2D echocardiography videos require extensive interaction with annotators and perform poorly on low-quality and noisy videos. We propose an automated and unsupervised method for the mitral valve segmentation based on a low dimensional embedding of the echocardiography vid…
