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arXiv 2311.08059eess.IVcs.CV
FS-Net：用于改善微视网膜血管结构提取的全尺度网络与自适应阈值
FS-Net: Full Scale Network and Adaptive Threshold for Improving Extraction of Micro-Retinal Vessel Structures
Skolkovo Institute of Science and Technology (Skoltech)（斯科尔科沃科学技术研究院（斯科尔泰克））；Artificial Intelligence Research Institute (AIRI)（人工智能研究院（AIRI））；University of Sharjah（沙迦大学）；Bian Que AI（扁鹊人工智能）；University College London（伦敦大学学院）；Research Institute for Medical and Health Sciences（医学与健康科学研究院）
Melaku N. Getahun, Oleg Y. Rogov, Dmitry V. Dylov, Andrey Somov, Ahmed Bouridane, Rifat Hamoudi
备注：
10 pages, 2 figures, under consideration at Pattern Recognition Letters
Retinal vascular segmentation, a widely researched topic in biomedical image processing, aims to reduce the workload of ophthalmologists in treating and detecting retinal disorders. Segmenting retinal vessels presents unique challenges; previous techniques often failed to effectively segment branches and microvascular structures. Recent neural network approaches struggle to balance local and global properties and frequently miss tiny end vessels, hindering the achievement of desired results. To address these issues in retinal vessel segmentation, we propose a comprehensive micro-vessel extraction mechanism based on an encoder-decoder neural network architecture. This network includes residual, encoder booster, bottleneck enhancement, squeeze, and excitation building blocks. These components synergistically enhance feature extraction and improve the prediction accuracy of the segmentation map. Our solution has been evaluated using the DRIVE, CHASE-DB1, and STARE datasets, yielding competitive results compared to previous studies. The AUC and accuracy on the DRIVE dataset are 0.9884 and 0.9702, respectively. For the CHASE-DB1 dataset, these scores are 0.9903 and 0.9755, respectively, and for the STARE dataset, they are 0.9916 and 0.9750. Given its accurate and robust performance, the proposed approach is a solid candidate for being implemented in real-life diagnostic centers and aiding ophthalmologists.
The accurate retinal vessel segmentation (RVS) is of great significance to assist doctors in the diagnosis of ophthalmology diseases and other systemic diseases. Manually designing a valid neural network architecture for retinal vessel segmentation requires high expertise and a large workload. In order to improve the performance of vessel segmentation and reduce the workload of manually designing neural network, we propose novel approach which applies neural architecture search (NAS) to optimize an encoder-decoder architecture for retinal vessel segmentation. A modified evolutionary algorithm …
Zhejiang University（浙江大学）；University of Alberta（阿尔伯塔大学）
Topological and geometrical analysis of retinal blood vessel is a cost-effective way for early detection of many common diseases. Meanwhile, automated vessel segmentation and vascular tree analysis are still lacking in terms of generalization capability. In this work, we construct a novel benchmark RETA with 81 labeled vessel masks aiming to facilitate retinal vessel analysis. A semi-automated coarse-to-fine workflow is proposed to annotating vessel pixels. During dataset construction, we strived to control inter-annotator variability and intra-annotator variability by performing multi-stage a…
Segmentation of retinal vessel images is critical to the diagnosis of retinopathy. Recently, convolutional neural networks have shown significant ability to extract the blood vessel structure. However, it remains challenging to refined segmentation for the capillaries and the edges of retinal vessels due to thickness inconsistencies and blurry boundaries. In this paper, we propose a novel deep neural network for retinal vessel segmentation based on shared decoder and pyramid-like loss (SPNet) to address the above problems. Specifically, we introduce a decoder-sharing mechanism to capture multi…
University of Science and Technology of China（中国科学技术大学）；Institute of Artificial Intelligence, Hefei Comprehensive National Science Center（合肥综合性国家科学中心人工智能研究院）
Accurate retinal vessel segmentation is challenging because of the complex texture of retinal vessels and low imaging contrast. Previous methods generally refine segmentation results by cascading multiple deep networks, which are time-consuming and inefficient. In this paper, we propose two novel methods to address these challenges. First, we devise a light-weight module, named multi-scale residual similarity gathering (MRSG), to generate pixel-wise adaptive filters (PA-Filters). Different from cascading multiple deep networks, only one PA-Filter layer can improve the segmentation results. Sec…
Eötvös Loránd University（罗兰大学）；Budapest University of Technology and Economics（布达佩斯技术与经济大学）；Jiangxi Normal University（江西师范大学）；Chinese Academy of Science（中国科学院）；Qinghai University（青海大学）
Reliable segmentation of retinal vessels can be employed as a way of monitoring and diagnosing certain diseases, such as diabetes and hypertension, as they affect the retinal vascular structure. In this work, we propose the Residual Spatial Attention Network (RSAN) for retinal vessel segmentation. RSAN employs a modified residual block structure that integrates DropBlock, which can not only be utilized to construct deep networks to extract more complex vascular features, but can also effectively alleviate the overfitting. Moreover, in order to further improve the representation capability of t…
Monash University（莫纳什大学）；Airdoc；NVIDIA AI Technology Center（英伟达人工智能技术中心）
Retinal vessel segmentation plays a key role in computer-aided screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Recently, deep learning-based retinal vessel segmentation algorithms have achieved remarkable performance. However, due to the domain shift problem, the performance of these algorithms often degrades when they are applied to new data that is different from the training data. Manually labeling new data for each test domain is often a time-consuming and laborious task. In this work, we explore unsupervised domain adaptation in retinal vessel segmen…
RBAD: A Dataset and Benchmark for Retinal Vessels Branching Angle Detection
School of Computing and Augmented Intelligence, Arizona State University（亚利桑那州立大学计算与增强智能学院）；Mayo Clinic（梅奥诊所）；School of Computing, Clemson University（克莱姆森大学计算学院）；Department of Electrical and Computer Engineering, Stevens Institute of Technology（史蒂文斯理工学院电气与计算机工程系）
From diagnosing neovascular diseases to detecting white matter lesions, accurate tiny vessel segmentation in fundus images is critical. Promising results for accurate vessel segmentation have been known. However, their effectiveness in segmenting tiny vessels is still limited. In this paper, we study retinal vessel segmentation by incorporating tiny vessel segmentation into our framework for the overall accurate vessel segmentation. To achieve this, we propose a new deep convolutional neural network (CNN) which divides vessel segmentation into two separate objectives. Specifically, we consider…
Beijing University of Posts and Telecommunications（北京邮电大学）；Institute of Automation, Chinese Academy of Sciences（中国科学院自动化研究所）；Henan University of Chinese Medicine（河南中医药大学）
3D to 2D retinal vessel segmentation is a challenging problem in Optical Coherence Tomography Angiography (OCTA) images. Accurate retinal vessel segmentation is important for the diagnosis and prevention of ophthalmic diseases. However, making full use of the 3D data of OCTA volumes is a vital factor for obtaining satisfactory segmentation results. In this paper, we propose a Progressive Attention-Enhanced Network (PAENet) based on attention mechanisms to extract rich feature representation. Specifically, the framework consists of two main parts, the three-dimensional feature learning path and…
Southern University of Science and Technology（南方科技大学）；The University of Hong Kong（香港大学）；Jiaxing Research Institute, Southern University of Science and Technology（南方科技大学嘉兴研究院）
Unsupervised domain adaptation has been proposed recently to tackle the so-called domain shift between training data and test data with different distributions. However, most of them only focus on single-target domain adaptation and cannot be applied to the scenario with multiple target domains. In this paper, we propose RVms, a novel unsupervised multi-target domain adaptation approach to segment retinal vessels (RVs) from multimodal and multicenter retinal images. RVms mainly consists of a style augmentation and transfer (SAT) module and a dual-teacher knowledge distillation (DTKD) module. S…
University of Bournemouth（伯恩茅斯大学）；IDIAP Research Institute（IDIAP研究所）；École de Technolgie Superieure de Montréal（蒙特利尔高等技术学院）；Diagnos Inc.（Diagnos公司）；CRCHUM University of Montreal Hospital Centre（蒙特利尔大学医院研究中心）
The segmentation of the retinal vasculature from eye fundus images represents one of the most fundamental tasks in retinal image analysis. Over recent years, increasingly complex approaches based on sophisticated Convolutional Neural Network architectures have been slowly pushing performance on well-established benchmark datasets. In this paper, we take a step back and analyze the real need of such complexity. Specifically, we demonstrate that a minimalistic version of a standard U-Net with several orders of magnitude less parameters, carefully trained and rigorously evaluated, closely approxi…
Synthetic optical coherence tomography angiographs for detailed retinal vessel segmentation without human annotations
Technical University of Munich（慕尼黑工业大学）；Imperial College London（帝国理工学院）；Helmholtz Zentrum Muenchen（亥姆霍兹慕尼黑中心）；University of Innsbruck（因斯布鲁克大学）；University of Oxford（牛津大学）；Moorfields Eye Hospital NHS Foundation Trust（摩尔菲尔德眼科医院国民保健服务基金会信托）；Boehringer Ingelheim Limited（勃林格殷格翰有限公司）；University College London（伦敦大学学院）；Cairo University（开罗大学）；Watany Eye Hospital（瓦塔尼眼科医院）；Heidelberg Engineering GmbH（海德堡工程有限公司）；University of Zurich（苏黎世大学）
Uncertainty-Aware Retinal Vessel Segmentation via Ensemble Distillation
University of Ibadan（伊巴迪安大学）；African Institute for Mathematical Sciences（非洲数学科学研究所）；University College London（伦敦大学学院）；Hertie Institute for Brain Health（海德研究所）
Nanjing University of Science and Technology（南京理工大学）；The First Affiliated Hospital with Nanjing Medical University（南京医科大学第一附属医院）
Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality that allows micron-level resolution to visualize the retinal microvasculature. The retinal vessel segmentation in OCTA images is still an open problem, and especially the thin and dense structure of the capillary plexus is an important challenge of this problem. In this work, we propose a novel image magnification network (IMN) for vessel segmentation in OCTA images. Contrary to the U-Net structure with a down-sampling encoder and up-sampling decoder, the proposed IMN adopts the design of up-sampling encod…
GrInAdapt: Scaling Retinal Vessel Structural Map Segmentation Through Grounding, Integrating and Adapting Multi-device, Multi-site, and Multi-modal Fundus Domains
Department of Bioengineering, University of Washington（华盛顿大学生物工程系）；Department of Electrical and Computer Engineering, University of Washington（华盛顿大学电气与计算机工程系）；Department of Ophthalmology, University of Washington（华盛顿大学眼科系）
Improve Retinal Artery/Vein Classification via Channel Couplin
Institute of Medical Technology, Peking University Health Science Center, Peking University, Beijing, China（北京大学医学部医学技术研究所）；Department of Biomedical Engineering, Peking University, Beijing, China（北京大学生物医学工程系）；National Biomedical Imaging Center, Peking University, Beijing, China（北京大学国家生物医学成像中心）；Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology（佐治亚理工学院生物医学工程系）；Emory University, Atlanta, GA, USA（埃默里大学）
University of Rochester（罗切斯特大学）；University of Rochester Medical Center（罗切斯特大学医学中心）；Houston Methodist Hospital（休斯顿卫理公会医院）；Weill Cornell Medical College（威尔康奈尔医学院）；Retina Consultants of Houston（休斯顿视网膜顾问中心）；Blanton Eye Institute（布兰顿眼科研究所）
While recent advances in deep learning have significantly advanced the state of the art for vessel detection in color fundus (CF) images, the success for detecting vessels in fluorescein angiography (FA) has been stymied due to the lack of labeled ground truth datasets. We propose a novel pipeline to detect retinal vessels in FA images using deep neural networks that reduces the effort required for generating labeled ground truth data by combining two key components: cross-modality transfer and human-in-the-loop learning. The cross-modality transfer exploits concurrently captured CF and fundus…
RVD: A Handheld Device-Based Fundus Video Dataset for Retinal Vessel Segmentation
The University of Queensland（昆士兰大学）；University of Technology Sydney（悉尼科技大学）；Australian National University（澳大利亚国立大学）；University of New South Wales（新南威尔士大学）；Victoria University（维多利亚大学）；Deakin University（迪肯大学）
Segmenting blood vessels in fundus imaging plays an important role in medical diagnosis. Many algorithms have been proposed. While deep Neural Networks have been attracting enormous attention from computer vision community recent years and several novel works have been done in terms of its application in retinal blood vessel segmentation, most of them are based on supervised learning which requires amount of labeled data, which is both scarce and expensive to obtain. We leverage the power of Deep Convolutional Neural Networks (DCNN) in feature learning, in this work, to achieve this ultimate g…
BioVessel-Net and RetinaMix: Unsupervised Retinal Vessel Segmentation from OCTA Images
University of Electronic Science and Technology of China（电子科技大学）；Southern Methodist University（南方法律大学）；University of Texas Southwestern Medical Center（德克萨斯西南医学中心）；University Medical Center Utrecht（乌得勒支大学医学中心）；Georgetown University（杰斐逊大学）；Sichuan Provincial People’s Hospital（四川省级人民医院）；University of Connecticut（康涅狄格大学）
University of California, Los Angeles（加利福尼亚大学洛杉矶分校）；Stein Eye Institute（斯坦眼科研究所）；VoxelCloud, Inc.（体素云公司）
The retinal vasculature provides important clues in the diagnosis and monitoring of systemic diseases including hypertension and diabetes. The microvascular system is of primary involvement in such conditions, and the retina is the only anatomical site where the microvasculature can be directly observed. The objective assessment of retinal vessels has long been considered a surrogate biomarker for systemic vascular diseases, and with recent advancements in retinal imaging and computer vision technologies, this topic has become the subject of renewed attention. In this paper, we present a novel…
Early diagnosis of retinal diseases such as diabetic retinopathy has had the attention of many researchers. Deep learning through the introduction of convolutional neural networks has become a prominent solution for image-related tasks such as classification and segmentation. Most tasks in image classification are handled by deep CNNs pretrained and evaluated on imagenet dataset. However, these models do not always translate to the best result on other datasets. Devising a neural network manually from scratch based on heuristics may not lead to an optimal model as there are numerous hyperparam…
The morphology of retinal blood vessels can indicate various diseases in the human body, and researchers have been working on automatic scanning and segmentation of retinal images to aid diagnosis. This project compares the performance of four neural network architectures in segmenting retinal images, using a combined dataset from different databases, namely the UNet, DR-VNet, UNet-ResNet and UNet-VGG.
University of California, Los Angeles（加利福尼亚大学洛杉矶分校）
The morphological attributes of retinal vessels, such as length, width, tortuosity and branching pattern and angles, play an important role in diagnosis, screening, treatment, and evaluation of various cardiovascular and ophthalmologic diseases such as diabetes, hypertension and arteriosclerosis. The crucial step before extracting these morphological characteristics of retinal vessels from retinal fundus images is vessel segmentation. In this work, we propose a method for retinal vessel segmentation based on fully convolutional networks. Thousands of patches are extracted from each retinal ima…
University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；University of Oregon（俄勒冈大学）
Retinal vessel segmentation from retinal images is an essential task for developing the computer-aided diagnosis system for retinal diseases. Efforts have been made on high-performance deep learning-based approaches to segment the retinal images in an end-to-end manner. However, the acquisition of retinal vessel images and segmentation labels requires onerous work from professional clinicians, which results in smaller training dataset with incomplete labels. As known, data-driven methods suffer from data insufficiency, and the models will easily over-fit the small-scale training data. Such a s…
Mentor, A Siemens Business（西门子旗下明导）；Lahore University of Management Sciences (LUMS)（拉合尔管理科学大学（LUMS））
Retinal blood vessels are considered to be the reliable diagnostic biomarkers of ophthalmologic and diabetic retinopathy. Monitoring and diagnosis totally depends on expert analysis of both thin and thick retinal vessels which has recently been carried out by various artificial intelligent techniques. Existing deep learning methods attempt to segment retinal vessels using a unified loss function optimized for both thin and thick vessels with equal importance. Due to variable thickness, biased distribution, and difference in spatial features of thin and thick vessels, unified loss function are …
Cairo higher institute for engineering, computer sciences and management（开罗工程、计算机科学与管理高等学院）；Majmaah University（迈加马大学）；high institute of engineering Shock academy Cairo（开罗肖克学院工程高等学院）
Diabetic retinopathy is the basic reason for visual deficiency. This paper introduces a programmed strategy to identify and dispense with the blood vessels. The location of the blood vessels is the fundamental stride in the discovery of diabetic retinopathy because the blood vessels are the typical elements of the retinal picture. The location of the blood vessels can help the ophthalmologists to recognize the sicknesses prior and quicker. The blood vessels recognized and wiped out by utilizing Gobar filter on two freely accessible retinal databases which are STARE and DRIVE. The exactness of …
MMM University of Technology（MMM理工大学）；National Institute of Technology, Hamirpur（哈米尔布尔国家理工学院）
Retinal blood vessels structure contains information about diseases like obesity, diabetes, hypertension and glaucoma. This information is very useful in identification and treatment of these fatal diseases. To obtain this information, there is need to segment these retinal vessels. Many kernel based methods have been given for segmentation of retinal vessels but their kernels are not appropriate to vessel profile cause poor performance. To overcome this, a new and efficient kernel based matched filter approach has been proposed. The new matched filter is used to generate the matched filter re…
Bahcesehir University（巴赫切谢希尔大学）；American University of Malta（马耳他美国大学）
Clinical screening with low-quality fundus images is challenging and significantly leads to misdiagnosis. This paper addresses the issue of improving the retinal image quality and vessel segmentation through retinal image restoration. More specifically, a cycle-consistent generative adversarial network (CycleGAN) with a convolution block attention module (CBAM) is used for retinal image restoration. A modified UNet is used for retinal vessel segmentation for the restored retinal images (CBAM-UNet). The proposed model consists of two generators and two discriminators. Generators translate image…
Trinity College Dublin（都柏林圣三一学院）；Maynooth University（梅努斯大学）；St. James’s Hospital（圣詹姆斯医院）
Accurate retinal vessel segmentation is an important task for many computer-aided diagnosis systems. Yet, it is still a challenging problem due to the complex vessel structures of an eye. Numerous vessel segmentation methods have been proposed recently, however more research is needed to deal with poor segmentation of thin and tiny vessels. To address this, we propose a new deep learning pipeline combining the efficiency of residual dense net blocks and, residual squeeze and excitation blocks. We validate experimentally our approach on three datasets and show that our pipeline outperforms curr…
KIIT Deemed to be University（KIIT被视为大学）；Pandit Deendayal Energy University（潘迪特·迪恩达亚尔能源大学）
Inner Retinal neurons are a most essential part of the retina and they are supplied with blood via retinal vessels. This paper primarily focuses on the segmentation of retinal vessels using a triple preprocessing approach. DRIVE database was taken into consideration and preprocessed by Gabor Filtering, Gaussian Blur, and Edge Detection by Sobel and Pruning. Segmentation was driven out by 2 proposed U-Net architectures. Both the architectures were compared in terms of all the standard performance metrics. Preprocessing generated varied interesting results which impacted the results shown by the…
Automated segmentation of vascular map in retinal images endeavors a potential benefit in diagnostic procedure of different ocular diseases. In this paper, we suggest a new unsupervised retinal blood vessel segmentation approach using top-hat transformation, contrast-limited adaptive histogram equalization (CLAHE), and 2-D Gabor wavelet filters. Initially, retinal image is preprocessed using top-hat morphological transformation followed by CLAHE to enhance only the blood vessel pixels in the presence of exudates, optic disc, and fovea. Then, multiscale 2-D Gabor wavelet filters are applied on …
Youtu Lab, Tencent（腾讯优图实验室）；School of Information Science and Engineering, Xiamen University（厦门大学信息科学与工程学院）
Retinal artery/vein (A/V) classification plays a critical role in the clinical biomarker study of how various systemic and cardiovascular diseases affect the retinal vessels. Conventional methods of automated A/V classification are generally complicated and heavily depend on the accurate vessel segmentation. In this paper, we propose a multi-task deep neural network with spatial activation mechanism that is able to segment full retinal vessel, artery and vein simultaneously, without the pre-requirement of vessel segmentation. The input module of the network integrates the domain knowledge of w…
Retinal vessel segmentation is of great interest for diagnosis of retinal vascular diseases. To further improve the performance of vessel segmentation, we propose IterNet, a new model based on UNet, with the ability to find obscured details of the vessel from the segmented vessel image itself, rather than the raw input image. IterNet consists of multiple iterations of a mini-UNet, which can be 4$\times$ deeper than the common UNet. IterNet also adopts the weight-sharing and skip-connection features to facilitate training; therefore, even with such a large architecture, IterNet can still learn …
A Novel Hybrid Approach for Retinal Vessel Segmentation with Dynamic Long-Range Dependency and Multi-Scale Retinal Edge Fusion Enhancement
School of Artificial Intelligence（人工智能学院）；Hebei University of Technology（河北工业大学）；NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases（国家卫生健康委员会激素与发育重点实验室和天津代谢疾病重点实验室）；Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology（天津医科大学楚生一纪念医院及内分泌研究所）
Dalian University of Technology（大连理工大学）；Ritsumeikan University（立命馆大学）
Many deep learning based methods have been proposed for retinal vessel segmentation, however few of them focus on the connectivity of segmented vessels, which is quite important for a practical computer-aided diagnosis system on retinal images. In this paper, we propose an efficient network to address this problem. A U-shape network is enhanced by introducing a semantics-guided module, which integrates the enriched semantics information to shallow layers for guiding the network to explore more powerful features. Besides, a recursive refinement iteratively applies the same network over the prev…
Beijing University of Posts and Telecommunications（北京邮电大学）
Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this problem suffers from various degrees of vessel thickness, perception of details, and contextual feature fusion. For addressing these challenges, a deep learning based method has been proposed and several customized modules have been integrated into the well-known encoder-decoder architecture U-net, which is mainly employed in medical image segmentation. Structu…
Cixi Institute of Biomedical Engineering, Ningbo Institute of Industrial Technology, Chinese Academy of Sciences（中国科学院宁波工业技术研究院慈溪生物医学工程研究所）；Inception Institute of Artificial Intelligence（起源人工智能研究院）；Keck School of Medicine, University of Southern California（南加州大学凯克医学院）；First Affiliated Hospital of Wenzhou Medical University（温州医科大学附属第一医院）；Southern University of Science and Technology（南方科技大学）；University of Liverpool（利物浦大学）
Optical Coherence Tomography Angiography (OCT-A) is a non-invasive imaging technique, and has been increasingly used to image the retinal vasculature at capillary level resolution. However, automated segmentation of retinal vessels in OCT-A has been under-studied due to various challenges such as low capillary visibility and high vessel complexity, despite its significance in understanding many eye-related diseases. In addition, there is no publicly available OCT-A dataset with manually graded vessels for training and validation. To address these issues, for the first time in the field of reti…
Recently, many methods based on hand-designed convolutional neural networks (CNNs) have achieved promising results in automatic retinal vessel segmentation. However, these CNNs remain constrained in capturing retinal vessels in complex fundus images. To improve their segmentation performance, these CNNs tend to have many parameters, which may lead to overfitting and high computational complexity. Moreover, the manual design of competitive CNNs is time-consuming and requires extensive empirical knowledge. Herein, a novel automated design method, called Genetic U-Net, is proposed to generate a U…
Budapest University of Technology and Economics（布达佩斯技术与经济大学）；Jiangxi Normal University（江西师范大学）；Eötvös Loránd University（厄特沃什·罗兰大学）；Shenyang Aerospace University（沈阳航空航天大学）
Retinal vessel segmentation plays an imaportant role in the field of retinal image analysis because changes in retinal vascular structure can aid in the diagnosis of diseases such as hypertension and diabetes. In recent research, numerous successful segmentation methods for fundus images have been proposed. But for other retinal imaging modalities, more research is needed to explore vascular extraction. In this work, we propose an efficient method to segment blood vessels in Scanning Laser Ophthalmoscopy (SLO) retinal images. Inspired by U-Net, "feature map reuse" and residual learning, we pro…
Computer Science Department, Henry Samueli School of Engineering Stein Eye Institute, David Geffen School of Medicine University of California, Los Angeles, CA 90095, USA
The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of convolutional neural networks to devise a reliable and fully automated method that can accurately detect, segment, and analyze retinal vessels. In particular, we propose a novel, fully convolutional deep neural network with an encoder-decoder architecture that employs dilated spatial pyramid pooling with multiple dilation rates to recover the lost content in the e…
University of Warwick（华威大学）；Griffith University（格里菲斯大学）；University of Adelaide（阿德莱德大学）；King’s College London（伦敦国王学院）
The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas, e.g, sudden brighter and darker areas and are inclined to predict a pixel to background due to the significant class imbalance, leading to high accuracy and specificity while low sensitivity. To that end, we propose a novel error attention refining network (ERA-Net) that is capable of learning and predicting the potential false predictions in a two-stage mann…
Retinal blood vessel can assist doctors in diagnosis of eye-related diseases such as diabetes and hypertension, and its segmentation is particularly important for automatic retinal image analysis. However, it is challenging to segment these vessels structures, especially the thin capillaries from the color retinal image due to low contrast and ambiguousness. In this paper, we propose pyramid U-Net for accurate retinal vessel segmentation. In pyramid U-Net, the proposed pyramid-scale aggregation blocks (PSABs) are employed in both the encoder and decoder to aggregate features at higher, current…
Deakin University（迪肯大学）；COMSATS University Islamabad（伊斯兰堡通信卫星大学）
Over recent years, increasingly complex approaches based on sophisticated convolutional neural network architectures have been slowly pushing performance on well-established benchmark datasets. In this paper, we take a step back to examine the real need for such complexity. We present RC-Net, a fully convolutional network, where the number of filters per layer is optimized to reduce feature overlapping and complexity. We also used skip connections to keep spatial information loss to a minimum by keeping the number of pooling operations in the network to a minimum. Two publicly available retina…
Fujian Agriculture and Forestry University（福建农林大学）；Digital Fujian Research Institute of Big Data for Agriculture and Forestry（数字福建农林大数据研究院）
Accurate segmentation of the blood vessels of the retina is an important step in clinical diagnosis of ophthalmic diseases. Many deep learning frameworks have come up for retinal blood vessels segmentation tasks. However, the complex vascular structure and uncertain pathological features make the blood vessel segmentation still very challenging. A novel U-shaped network named Multi-module Concatenation which is based on Atrous convolution and multi-kernel pooling is put forward to retinal vessels segmentation in this paper. The proposed network structure retains three layers the essential stru…
