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arXiv 2311.03371physics.med-pheess.IV

基于AI的门控非增强CT心腔容积自动测量

AI-based, automated chamber volumetry from gated, non-contrast CT

Athira J Jacob, Ola Abdelkarim, Salma Zook, Kristian Hay Kragholm, Prantik Gupta, Myra Cocker, Juan Ramirez Giraldo, Jim O Doherty, Max Schoebinger, Chris Schwe… 展开作者

Athira J Jacob, Ola Abdelkarim, Salma Zook, Kristian Hay Kragholm, Prantik Gupta, Myra Cocker, Juan Ramirez Giraldo, Jim O Doherty, Max Schoebinger, Chris Schwemmer, Mehmet A Gulsun, Saikiran Rapaka, Puneet Sharma, Su-Min Chang

AI总结:

本研究提出一种基于AI的门控非增强CT心腔容积与心肌质量全自动测量方法,经420例患者数据验证,结果与增强CT血管造影真值一致性好,可用于心衰筛查。

摘要:

研究背景:通过门控非增强心脏CT(NCCT)扫描获得准确的心腔容积测量结果,对心力衰竭的潜在筛查具有实用价值。研究目的:验证一种全新的、基于AI的全自动方法,该方法可通过NCCT扫描量化心脏容积与心肌质量,并将其与增强CT血管造影(CCTA)的结果进行对比。研究方法:本研究回顾性收集了1051例连续患者的队列,排除携带心脏装置的患者后,共有420例患者同时拥有舒张中期的NCCT和CCTA扫描数据,以CCTA扫描的测量结果作为真值。研究结果:NCCT的容积计算结果与真值一致性良好。各指标的容积差异[95%置信区间]及相关系数分别为:左心室总容积-9.6[-45;26]mL,r=0.98;左心房容积-5.4[-24;13]mL,r=0.95;右心室容积-8.7[-45;28]mL,r=0.94;右心房容积-5.2[-27;17]mL,r=0.92;左心室血池容积-3.2[-42;36]mL,r=0.91;左心室壁质量-6.7[-39;26]g,r=0.94。所有心腔的平均相对容积误差均低于7%。研究结论:通过NCCT扫描全自动评估心腔容积是可行的,且与增强检查获得的容积结果相关性良好。

英文摘要:

Background: Accurate chamber volumetry from gated, non-contrast cardiac CT (NCCT) scans can be useful for potential screening of heart failure. Objectives: To validate a new, fully automated, AI-based method for cardiac volume and myocardial mass quantification from NCCT scans compared to contrasted CT Angiography (CCTA). Methods: Of a retrospectively collected cohort of 1051 consecutive patients, 420 patients had both NCCT and CCTA scans at mid-diastolic phase, excluding patients with cardiac devices. Ground truth values were obtained from the CCTA scans. Results: The NCCT volume computation shows good agreement with ground truth values. Volume differences [95% CI ] and correlation coefficients were: -9.6 [-45; 26] mL, r = 0.98 for LV Total, -5.4 [-24; 13] mL, r = 0.95 for LA, -8.7 [-45; 28] mL, r = 0.94 for RV, -5.2 [-27; 17] mL, r = 0.92 for RA, -3.2 [-42; 36] mL, r = 0.91 for LV blood pool, and -6.7 [-39; 26] g, r = 0.94 for LV wall mass, respectively. Mean relative volume errors of less than 7% were obtained for all chambers. Conclusions: Fully automated assessment of chamber volumes from NCCT scans is feasible and correlates well with volumes obtained from contrast study.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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