This paper addresses the problem of providing robust estimators under a functional logistic regression model. Logistic regression is a popular tool in classification problems with two populations. As in functional linear regression, regularization tools are needed to compute estimators for the functional slope. The traditional methods are based on dimension reduction or penalization combined with maximum likelihood or quasi--likelihood techniques and for that reason, they may be affected by misclassified points especially if they are associated to functional covariates with atypical behaviour. The proposal given in this paper adapts some of the best practices used when the covariates are finite--dimensional to provide reliable estimations. Under regularity conditions, consistency of the resulting estimators and rates of convergence for the predictions are derived. A numerical study illustrates the finite sample performance of the proposed method and reveals its stability under different contamination scenarios. A real data example is also presented.
Carnegie Mellon University（卡内基梅隆大学）；Institute of Science and Technology Austria（奥地利科学技术研究所）
Following the publication of an attack on genome-wide association studies (GWAS) data proposed by Homer et al., considerable attention has been given to developing methods for releasing GWAS data in a privacy-preserving way. Here, we develop an end-to-end differentially private method for solving regression problems with convex penalty functions and selecting the penalty parameters by cross-validation. In particular, we focus on penalized logistic regression with elastic-net regularization, a method widely used to in GWAS analyses to identify disease-causing genes. We show how a differentially…
This article presents methods for constructing an asymptotic hyperbolic band under the multiple logistic regression model when the predictor variables are restricted to a specific region $\mathscr{X}$. Scheffé's method yields unnecessarily wide, and hence conservative, bands if the predictor variables can be restricted to a certain region. Piegorsch and Casella (1988) developed a procedure to build an asymptotic confidence band for the multiple logistic regression model over particular regions. Those regions are shown to be special cases of the region $\mathscr{X}$, which was first investigate…
Feature selection is a standard approach to understanding and modeling high-dimensional classification data, but the corresponding statistical methods hinge on tuning parameters that are difficult to calibrate. In particular, existing calibration schemes in the logistic regression framework lack any finite sample guarantees. In this paper, we introduce a novel calibration scheme for $\ell_1$-penalized logistic regression. It is based on simple tests along the tuning parameter path and is equipped with optimal guarantees for feature selection. It is also amenable to easy and efficient implement…
This article presents methods for the construction of two-sided and one-sided simultaneous hyperbolic bands for the logistic and probit regression models when the predictor variable is restricted to a given interval. The bands are constructed based on the asymptotic properties of the maximum likelihood estimators. Past articles have considered building two-sided asymptotic confidence bands for the logistic model, such as Piegorsch and Casella (1988). However, the confidence bands given by Piegorsch and Casella are conservative under a single interval restriction, and it is shown in this articl…
This is a note on logistic regression models and logistic kernel machine models. It contains derivations to some of the expressions in a paper -- SNP Set Analysis for Detecting Disease Association Using Exon Sequence Data -- submitted to BMC proceedings by these authors.
School of Engineering, Computing and Mathematics（工程、计算与数学学院）；Oxford Brookes University（牛津布鲁克斯大学）
The notion of belief likelihood function of repeated trials is introduced, whenever the uncertainty for individual trials is encoded by a belief measure (a finite random set). This generalises the traditional likelihood function, and provides a natural setting for belief inference from statistical data. Factorisation results are proven for the case in which conjunctive or disjunctive combination are employed, leading to analytical expressions for the lower and upper likelihoods of `sharp' samples in the case of Bernoulli trials, and to the formulation of a generalised logistic regression frame…
We propose an optimal estimating equation for logistic regression with linked data while accounting for false positives. It builds on a previous solution but estimates the regression coefficients with a smaller variance, in large samples.
This study aims to show the fundamental difference between logistic regression and Bayesian classifiers in the case of exponential and unexponential families of distributions, yielding the following findings. First, the logistic regression is a less general representation of a Bayesian classifier. Second, one should suppose distributions of classes for the correct specification of logistic regression equations. Third, in specific cases, there is no difference between predicted probabilities from correctly specified generative Bayesian classifier and discriminative logistic regression.
Analyzing polytomous response from a complex survey scheme, like stratified or cluster sampling is very crucial in several socio-economics applications. We present a class of minimum quasi weighted density power divergence estimators for the polytomous logistic regression model with such a complex survey. This family of semiparametric estimators is a robust generalization of the maximum quasi weighted likelihood estimator exploiting the advantages of the popular density power divergence measure. Accordingly robust estimators for the design effects are also derived. Robust testing of general li…
This paper considers the Liu estimator in the multinomial logistic regression model. We propose some different estimators of the biasing parameter. The mean square error (MSE) is considered as the performance criterion. In order to compare the performance of the estimators, we performed a Monte Carlo simulation study. According to the results of the simulation study, we found that increasing the correlation between the independent variables and the number of regressors has a negative effect on the MSE. However, when the sample size increases the MSE decreases even when the correlation between …
Explicitly accounting for all applicable independent variables, even when the model being tested does not, is critical in testing goodness-of-fit for logistic regression. This can increase statistical power by orders of magnitude.
This paper infers a single parameter in non-sparse logistic regression models. By transforming the null hypothesis into a moment condition, we construct the test statistic and obtain the asymptotic null distribution. Numerical experiments show that our method performs well.
A new approach for feature extraction from time series is proposed in this paper. This approach consists of a specific regression model incorporating a discrete hidden logistic process. The model parameters are estimated by the maximum likelihood method performed by a dedicated Expectation Maximization (EM) algorithm. The parameters of the hidden logistic process, in the inner loop of the EM algorithm, are estimated using a multi-class Iterative Reweighted Least-Squares (IRLS) algorithm. A piecewise regression algorithm and its iterative variant have also been considered for comparisons. An ex…
In several FICO studies logistic regression has been shown to be a very competitive technology for developing unrestricted scoring models, especially for performance metrics like ROC area. Application of logistic regression has been hampered by the lack of software to handle complex score engineering such as shape and pattern constraints. The purpose of this paper is to develop a sequential quadratic programming algorithm for score engineered logistic regression. This approach is based on a simple Taylor series expansion of minus log likelihood, which is locally quadratic. and fits in with the…
In this paper we propose a principal component Liu-type logistic estimator by combining the principal component logistic regression estimator and Liu-type logistic estimator to overcome the multicollinearity problem. The superiority of the new estimator over some related estimators are studied under the asymptotic mean squared error matrix. A Monte Carlo simulation experiment is designed to compare the performances of the estimators using mean squared error criterion. Finally, a conclusion section is presented.
Imperial College London（帝国理工学院）；Vrije Universiteit Amsterdam（阿姆斯特丹自由大学）
Variational Bayes (VB) is a popular scalable alternative to Markov chain Monte Carlo for Bayesian inference. We study a mean-field spike and slab VB approximation of widely used Bayesian model selection priors in sparse high-dimensional logistic regression. We provide non-asymptotic theoretical guarantees for the VB posterior in both $\ell_2$ and prediction loss for a sparse truth, giving optimal (minimax) convergence rates. Since the VB algorithm does not depend on the unknown truth to achieve optimality, our results shed light on effective prior choices. We confirm the improved performance o…
Recently, a very attractive logistic regression inference method for exponential family Gibbs spatial point processes was introduced. We combined it with the technique of quadratic tangential variational approximation and derived a new Bayesian technique for analysing spatial point patterns. The technique is described in detail, and demonstrated on numerical examples.
Tel Aviv University（特拉维夫大学）；The Open University of Israel（以色列开放大学）
In this paper we consider high-dimensional multiclass classification by sparse multinomial logistic regression. We propose first a feature selection procedure based on penalized maximum likelihood with a complexity penalty on the model size and derive the nonasymptotic bounds for misclassification excess risk of the resulting classifier. We establish also their tightness by deriving the corresponding minimax lower bounds. In particular, we show that there exist two regimes corresponding to small and large number of classes. The bounds can be reduced under the additional low noise condition. To…
In this paper we discuss how to evaluate the differences between fitted logistic regression models across sub-populations. Our motivating example is in studying computerized diagnosis for learning disabilities, where sub-populations based on gender may or may not require separate models. In this context, significance tests for hypotheses of no difference between populations may provide perverse incentives, as larger variances and smaller samples increase the probability of not-rejecting the null. We argue that equivalence testing for a prespecified tolerance level on population differences inc…
Logistic regression has been widely applied in the field of biomedical research for a long time. In some applications, covariates of interest have a natural structure, such as being a matrix, at the time of collection. The rows and columns of the covariate matrix then have certain physical meanings, and they must contain useful information regarding the response. If we simply stack the covariate matrix as a vector and fit the conventional logistic regression model, relevant information can be lost, and the problem of inefficiency will arise. Motivated from these reasons, we propose in this pap…
This article develops the theoretical framework needed to study the multinomial logistic regression model for complex sample design with pseudo minimum phi-divergence estimators. Through a numerical example and simulation study new estimators are proposed for the parameter of the logistic regression model with overdispersed multinomial distributions for the response variables, the pseudo minimum Cressie-Read divergence estimators, as well as new estimators for the intra-cluster correlation coefficient. The results show that the Binder's method for the intra-cluster correlation coefficient exhi…
We obtain new mathematical properties of the exponentiated odd log-logistic family of distributions, and of its special case named the exponentiated odd log-logistic Weibull, and its log transformed. A new location and scale regression model is constructed, and some simulations are carried out to verify the behavior of the maximum likelihood estimators, and of the modified deviance-based residuals. The methodology is applied to the Japanese-Brazilian emigration data.
This paper looks at effects, due to the boundary, on inference in logistic regression. It shows that first -- and, indeed, higher -- order asymptotic results are not uniform across the model. Near the boundary, effects such as high skewness, discreteness and collinearity dominate, any of which could render inference based on asymptotic normality suspect. A highly interpretable diagnostic tool is proposed allowing the analyst to check if the boundary is going to have an appreciable effect on standard inferential techniques.
Logistic regression is an important statistical tool for assessing the probability of an outcome based upon some predictive variables. Standard methods can only deal with precisely known data, however many datasets have uncertainties which traditional methods either reduce to a single point or completely disregarded. In this paper we show that it is possible to include these uncertainties by considering an imprecise logistic regression model using the set of possible models that can be obtained from values from within the intervals. This has the advantage of clearly expressing the epistemic un…
In order to overcome multicollinearity, we propose a stochastic restricted Liu-type max- imum likelihood estimator by incorporating Liu-type maximum likelihood estimator (Inan and Erdo- gan, 2013) to the logistic regression model when the linear restrictions are stochastic. We also discuss the properties of the new estimator. Moreover, we give a method to choose the biasing parameter in the new estimator. Finally, a simulation study is given to show the performance of the new estimator.
We consider Bayesian logistic regression models with group-structured covariates. In high-dimensional settings, it is often assumed that only small portion of groups are significant, thus consistent group selection is of significant importance. While consistent frequentist group selection methods have been proposed, theoretical properties of Bayesian group selection methods for logistic regression models have not been investigated yet. In this paper, we consider a hierarchical group spike and slab prior for logistic regression models in high-dimensional settings. Under mild conditions, we esta…
Consider a set of categorical variables $\mathcal{P}$ where at least one, denoted by $Y$, is binary. The log-linear model that describes the counts in the resulting contingency table implies a specific logistic regression model, with the binary variable as the outcome. Extending results in Christensen (1997), by also considering the case where factors present in the contingency table disappear from the logistic regression model, we prove that the Maximum Likelihood Estimate (MLE) for the parameters of the logistic regression equals the MLE for the corresponding parameters of the log-linear mod…
Department of Indutrial Engineering and Operations Research, University of California, Berkeley（加州大学伯克利分校工业工程与运筹学系）
In logistic regression, it is often desirable to utilize regularization to promote sparse solutions, particularly for problems with a large number of features compared to available labels. In this paper, we present screening rules that safely remove features from logistic regression with $\ell_0-\ell_2$ regularization before solving the problem. The proposed safe screening rules are based on lower bounds from the Fenchel dual of strong conic relaxations of the logistic regression problem. Numerical experiments with real and synthetic data suggest that a high percentage of the features can be e…
Objective: To investigate the impact of different logistic regression estimators applied to RDS samples obtained by simulation and real data. Methods: Four simulated populations were created combining different connectivity models, levels of clusterization and infection processes. Each subject in the population received two attributes, only one of them related to the infection process. From each population, RDS samples with different sizes were obtained. Similarly, RDS samples were obtained from a real-world dataset. Three logistic regression estimators were applied to assess the association b…
We propose a new algorithm called PLUTO for building logistic regression trees to binary response data. PLUTO can capture the nonlinear and interaction patterns in messy data by recursively partitioning the sample space. It fits a simple or a multiple linear logistic regression model in each partition. PLUTO employs the cyclical coordinate descent method for estimation of multiple linear logistic regression models with elastic net penalties, which allows it to deal with high-dimensional data efficiently. The tree structure comprises a graphical description of the data. Together with the logist…
In this letter, we consider the problem of field estimation using binary measurements. Previous work has formulated the problem as a parameter estimation problem, with the parameter estimation carried out in an online manner using sequential Monte Carlo techniques. In the current work, we consider an alternative approach to the parameter estimation based on online logistic regression. The developed algorithm is less computationally intensive than the sequential Monte Carlo approach, while having more reliable estimation performance.
Consider a set of categorical variables where at least one of them is binary. The log-linear model that describes the counts in the resulting contingency table implies a specific logistic regression model, with the binary variable as the outcome. Within the Bayesian framework, the $g$-prior and mixtures of $g$-priors are commonly assigned to the parameters of a generalized linear model. We prove that assigning a $g$-prior (or a mixture of $g$-priors) to the parameters of a certain log-linear model designates a $g$-prior (or a mixture of $g$-priors) on the parameters of the corresponding logist…
A new family of minimum distance estimators for binary logistic regression models based on $ϕ$-divergence measures is introduced. The so called "pseudo minimum phi-divergence estimator"(PM$ϕ$E) family is presented as an extension of "minimum phi-divergence estimator" (M$ϕ$E) for general sample survey designs and contains, as a particular case, the pseudo maximum likelihood estimator (PMLE) considered in Roberts et al. \cite{r}. Through a simulation study it is shown that some PM$ϕ$Es have a better behaviour, in terms of efficiency, than the PMLE.
We propose a penalized likelihood method that simultaneously fits the multinomial logistic regression model and combines subsets of the response categories. The penalty is non differentiable when pairs of columns in the optimization variable are equal. This encourages pairwise equality of these columns in the estimator, which corresponds to response category combination. We use an alternating direction method of multipliers algorithm to compute the estimator and we discuss the algorithm's convergence. Prediction and model selection are also addressed.
We introduce Bayesian additive regression trees (BART) for log-linear models including multinomial logistic regression and count regression with zero-inflation and overdispersion. BART has been applied to nonparametric mean regression and binary classification problems in a range of settings. However, existing applications of BART have been limited to models for Gaussian "data", either observed or latent. This is primarily because efficient MCMC algorithms are available for Gaussian likelihoods. But while many useful models are naturally cast in terms of latent Gaussian variables, many others …
This paper derives a new family of estimators, namely the minimum density power divergence estimators, as a robust generalization of the maximum likelihood estimator for the polytomous logistic regression model. Based on these estimators, a family of Wald-type test statistics for linear hypotheses is introduced. Robustness properties of both the proposed estimators and the test statistics are theoretically studied through the classical influence function analysis. Appropriate real life examples are presented to justify the requirement of suitable robust statistical procedures in place of the l…
Recently, graph (network) data is an emerging research area in artificial intelligence, machine learning and statistics. In this work, we are interested in whether node's labels (people's responses) are affected by their neighbor's features (friends' characteristics). We propose a novel latent logistic regression model to describe the network dependence with binary responses. The key advantage of our proposed model is that a latent binary indicator is introduced to indicate whether a node is susceptible to the influence of its neighbour. A score-type test is proposed to diagnose the existence …
Logistic regression models for binomial responses are routinely used in statistical practice. However, the maximum likelihood estimate may not exist due to data separability. We address this issue by considering a conjugate prior penalty which always produces finite estimates. Such a specification has a clear Bayesian interpretation and enjoys several invariance properties, making it an appealing prior choice. We show that the proposed method leads to an accurate approximation of the reduced-bias approach of Firth (1993), resulting in estimators with smaller asymptotic bias than the maximum-li…
Compared to the conditional mean as a simple point estimator, the conditional density function is more informative to describe the distributions with multi-modality, asymmetry or heteroskedasticity. In this paper, we propose a novel parametric conditional density estimation method by showing the connection between the general density and the likelihood function of inhomogeneous Poisson process models. The maximum likelihood estimates can be obtained via weighted logistic regressions, and the computation can be significantly relaxed by combining a block-wise alternating maximization scheme and …
Fully robust versions of the elastic net estimator are introduced for linear and logistic regression. The algorithms to compute the estimators are based on the idea of repeatedly applying the non-robust classical estimators to data subsets only. It is shown how outlier-free subsets can be identified efficiently, and how appropriate tuning parameters for the elastic net penalties can be selected. A final reweighting step improves the efficiency of the estimators. Simulation studies compare with non-robust and other competing robust estimators and reveal the superiority of the newly proposed met…
Firth-type logistic regression has become a standard approach for the analysis of binary outcomes with small samples. Whereas it reduces the bias in maximum likelihood estimates of coefficients, bias towards 1/2 is introduced in the predicted probabilities. The stronger the imbalance of the outcome, the more severe is the bias in the predicted probabilities. We propose two simple modifications of Firth-type logistic regression resulting in unbiased predicted probabilities. The first corrects the predicted probabilities by a post-hoc adjustment of the intercept. The other is based on an alterna…
An accurately identified maximum tolerated dose (MTD) serves as the cornerstone of successful subsequent phases in oncology drug development. Bayesian logistic regression model (BLRM) is a popular and versatile model-based dose-finding design. However, BLRM with original overdose control strategy has been reported to be safe but "excessively conservative". In this manuscript, we investigate the reason for conservativeness and point out that a major reason could be the lack of appropriate underdose control. We propose designs that balance overdose and underdose control to improve the performanc…
This paper describes a method for a model-based analysis of clinical safety data called multivariate Bayesian logistic regression (MBLR). Parallel logistic regression models are fit to a set of medically related issues, or response variables, and MBLR allows information from the different issues to "borrow strength" from each other. The method is especially suited to sparse response data, as often occurs when fine-grained adverse events are collected from subjects in studies sized more for efficacy than for safety investigations. A combined analysis of data from multiple studies can be perform…
