The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To address this issue, we propose using progressive text prompts as prior knowledge to guide the segmentation process. Our model consists of two stages. In the first stage, we perform contrastive learning on natural images to pretrain a powerful prior prompt encoder (PPE). This PPE leverages text prior prompts to generate multimodality features. In the second stage, medical image and text prior prompts are sent into the PPE inherited from the first stage to achieve the downstream medical image segmentation task. A multiscale feature fusion block (MSFF) combines the features from the PPE to produce multiscale multimodality features. These two progressive features not only bridge the semantic gap but also improve prediction accuracy. Finally, an UpAttention block refines the predicted results by merging the image and text features. This design provides a simple and accurate way to leverage multiscale progressive text prior prompts for medical image segmentation. Compared with using only images, our model achieves high-quality results with low data annotation costs. Moreover, our model not only has excellent reliability and validity on medical images but also performs well on natural images. The experimental results on different image datasets demonstrate that our model is effective and robust for image segmentation.
MLRU++: Multiscale Lightweight Residual UNETR++ with Attention for Efficient 3D Medical Image Segmentation
AI Research Lab, Department of Computer Science（人工智能研究实验室、计算机科学系）；Biomedical & Translational Sciences, Sanford School of Medicine（生物医学与转化科学、桑福德医学院）；University Of South Dakota（南达科他大学）
Indian Statistical Institute（印度统计研究所）；Østfold University College（东福尔大学学院）；SimulaMet；UiT The Arctic University of Norway（挪威北极大学）；Oslo Metropolitan University（奥斯陆城市大学）
Medical image segmentation can provide detailed information for clinical analysis which can be useful for scenarios where the detailed location of a finding is important. Knowing the location of disease can play a vital role in treatment and decision-making. Convolutional neural network (CNN) based encoder-decoder techniques have advanced the performance of automated medical image segmentation systems. Several such CNN-based methodologies utilize techniques such as spatial- and channel-wise attention to enhance performance. Another technique that has drawn attention in recent years is residual…
Medical image computing has advanced rapidly with the advent of deep learning techniques such as convolutional neural networks. Deep convolutional neural networks can perform exceedingly well given full supervision. However, the success of such fully-supervised models for various image analysis tasks (e.g., anatomy or lesion segmentation from medical images) is limited to the availability of massive amounts of labeled data. Given small sample sizes, such models are prohibitively data biased with large domain shift. To tackle this problem, we propose a novel end-to-end medical image segmentatio…
LGMSNet: Thinning a medical image segmentation model via dual-level multiscale fusion
School of Biomedical Engineering, Division of Life Sciences；Medicine, University of Science；Center for Medical Imaging, Robotics, Analytic Computing \& Learning (MIRACLE), Suzhou Institute for Advance Research, USTC, Suzhou, 215123, China；Key Laboratory of Intelligent Information Processing of Chinese Academy of Sciences (CAS), Institute of Computing Technology, CAS, Beijing, 100190, China；Jiangsu Provincial Key Laboratory of Multimodal Digital Twin Technology, Suzhou, 215123, China；State Key Laboratory of Precision \& Intelligent Chemistry, USTC, Hefei, China
Multiscale Switch for Semi-Supervised and Contrastive Learning in Medical Ultrasound Image Segmentation
Department of Health Technology and Informatics, The Hong Kong Polytechnic University（健康科技与信息学系，香港理工大学）；Centre for Smart Health and School of Nursing, The Hong Kong Polytechnic University（智能健康中心及护理学院，香港理工大学）；Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong（影像与介入放射科，香港中文大学）
ProCNS: Progressive Prototype Calibration and Noise Suppression for Weakly-Supervised Medical Image Segmentation
Southern University of Science and Technology（南方科技大学）；University of Hong Kong（香港大学）；Jiaxing Research Institute, Southern University of Science and Technology（南方科技大学嘉兴研究院）
Rethinking Medical Landmark Localization with Prototype Learning-based Progressive Offset Correction
Shenzhen University（深圳大学）；Centre for Artificial Intelligence and Robotics, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences（中国科学院香港创新研究院人工智能与机器人中心）；Boston Children’s Hospital（波士顿儿童医院）；Harvard Medical School（哈佛医学院）；School of Artificial Intelligence, Shenzhen University（深圳大学人工智能学院）；School of Biomedical Engineering and Informatics, Nanjing Medical University（南京医科大学生物医学工程与信息学院）；National Engineering Laboratory for Big Data System Computing Technology, Shenzhen University（深圳大学大数据系统计算技术国家工程实验室）
The state-of-the-art models for medical image segmentation are variants of U-Net and fully convolutional networks (FCN). Despite their success, these models have two limitations: (1) their optimal depth is apriori unknown, requiring extensive architecture search or inefficient ensemble of models of varying depths; and (2) their skip connections impose an unnecessarily restrictive fusion scheme, forcing aggregation only at the same-scale feature maps of the encoder and decoder sub-networks. To overcome these two limitations, we propose UNet++, a new neural architecture for semantic and instance…
Xinjiang University（新疆大学）；Software College, Xinjiang University（新疆大学软件学院）；Network Center, Xinjiang University（新疆大学网络中心）
To better retain the deep features of an image and solve the sparsity problem of the end-to-end segmentation model, we propose a new deep convolutional network model for medical image pixel segmentation, called MC-Net. The core of this network model consists of four parts, namely, an encoder network, a multiple max-pooling integration module, a cross multiscale deconvolution decoder network and a pixel-level classification layer. In the network structure of the encoder, we use multiscale convolution instead of the traditional single-channel convolution. The multiple max-pooling integration mod…
Progressive Growing of Patch Size: Curriculum Learning for Accelerated and Improved Medical Image Segmentation
School of Computation, Information and Technology, Technical University Munich（技术大学慕尼黑计算、信息与技术学院）；Department of Radiation Oncology, TUM School of Medicine, TUM University Hospital rechts der Isar, Technical University of Munich（肿瘤放射治疗科，TUM医学院，TUM大学医院rechts der Isar，技术大学慕尼黑）；Institute of Machine Learning in Biomedical Imaging, Helmholtz Munich（生物医学影像中的机器学习研究所，海德堡慕尼黑）；Institute of Radiation Medicine, Helmholtz Center Munich（放射医学研究所，海德堡慕尼黑）；Munich Center of Machine Learning (MCML)（慕尼黑机器学习中心）；School of Biomedical Engineering and Imaging Sciences, King’s College London（生物医学工程与成像科学学院，伦敦国王学院）；Departament de Matemàtiques i Informàtica, Barcelona Artificial Intelligence in Medicine Lab (BCN-AIM), Universitat de Barcelona（数学与计算机科学系，巴塞罗那人工智能在医学实验室（BCN-AIM），巴塞罗那大学）
KANResDiff: Learning Local Residual Diffusion via Kolmogorov-Arnold Network for Ambiguous Medical Image Segmentation
Faculty of Computing, Harbin Institute of Technology（哈尔滨工业大学计算学部）；College of Computer and Control Engineering, Northeast Forestry University（东北林业大学计算机与控制工程学院）；Case Western Reserve University（凯斯西储大学）
Univ. Bordeaux（波尔多大学）；Bordeaux INP（波尔多国立高等综合理工学院）；CNRS（法国国家科学研究中心）；LaBRI（波尔多计算机科学实验室）；IMB（波尔多数学研究所）；ITACA（信息与通信技术应用研究所）；Universitat Politècnica de València（瓦伦西亚理工大学）
Semi-supervised learning (SSL) uses unlabeled data to compensate for the scarcity of annotated images and the lack of method generalization to unseen domains, two usual problems in medical segmentation tasks. In this work, we propose POPCORN, a novel method combining consistency regularization and pseudo-labeling designed for image segmentation. The proposed framework uses high-level regularization to constrain our segmentation model to use similar latent features for images with similar segmentations. POPCORN estimates a proximity graph to select data from easiest ones to more difficult ones,…
Semi-supervised semantic segmentation focuses on the exploration of a small amount of labeled data and a large amount of unlabeled data, which is more in line with the demands of real-world image understanding applications. However, it is still hindered by the inability to fully and effectively leverage unlabeled images. In this paper, we reveal that cross-window consistency (CWC) is helpful in comprehensively extracting auxiliary supervision from unlabeled data. Additionally, we propose a novel CWC-driven progressive learning framework to optimize the deep network by mining weak-to-strong con…
CAD: Confidence-Aware Adaptive Displacement for Semi-Supervised Medical Image Segmentation
College of Information and Intelligence, Hunan Agricultural University（湖南农业大学信息与智能科学学院）；School of Computer Science and Engineering, University of New South Wales（新南威尔士大学计算机科学与工程学院）
VinAI Research（VinAI研究院）；VinUniversity（Vin大学）；University of Arkansas（阿肯色大学）；Stony Brook University（石溪大学）
The objective of this work is to segment high-resolution images without overloading GPU memory usage or losing the fine details in the output segmentation map. The memory constraint means that we must either downsample the big image or divide the image into local patches for separate processing. However, the former approach would lose the fine details, while the latter can be ambiguous due to the lack of a global picture. In this work, we present MagNet, a multi-scale framework that resolves local ambiguity by looking at the image at multiple magnification levels. MagNet has multiple processin…
University of Tübingen（图宾根大学）；Max Planck Institute for Intelligent Systems（马克斯·普朗克智能系统研究所）
Image-to-image translation plays a vital role in tackling various medical imaging tasks such as attenuation correction, motion correction, undersampled reconstruction, and denoising. Generative adversarial networks have been shown to achieve the state-of-the-art in generating high fidelity images for these tasks. However, the state-of-the-art GAN-based frameworks do not estimate the uncertainty in the predictions made by the network that is essential for making informed medical decisions and subsequent revision by medical experts and has recently been shown to improve the performance and inter…
ImageFlowNet: Forecasting Multiscale Image-Level Trajectories of Disease Progression with Irregularly-Sampled Longitudinal Medical Images
Yale University（耶鲁大学）；University of California, San Francisco（加州大学旧金山分校）；Mila - Quebec AI Institute（魁北克AI研究所）；Université de Montréal（蒙特利尔大学）；McGill University（麦吉尔大学）；Northern California Retina Vitreous Associates（北加州视网膜与玻璃体协会）
In medical imaging, obtaining large amounts of labeled data is often a hurdle, because annotations and pathologies are scarce. Anomaly detection is a method that is capable of detecting unseen abnormal data while only being trained on normal (unannotated) data. Several algorithms based on generative adversarial networks (GANs) exist to perform this task, yet certain limitations are in place because of the instability of GANs. This paper proposes a new method by combining an existing method, GANomaly, with progressively growing GANs. The latter is known to be more stable, considering its abilit…
Multimodal Medical Endoscopic Image Analysis via Progressive Disentangle-aware Contrastive Learning
Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（深圳先进技术研究院，中国科学院）；First Affiliated Hospital, Sun Yat-sen University（中山大学第一附属医院）；College of Big Data and Internet, Shenzhen Technology University（深圳技术大学大数据与互联网学院）
COMSATS University Islamabad（伊斯兰堡COMSATS大学）；Umeå University（于默奥大学）
U-Net is a widely adopted neural network in the domain of medical image segmentation. Despite its quick embracement by the medical imaging community, its performance suffers on complicated datasets. The problem can be ascribed to its simple feature extracting blocks: encoder/decoder, and the semantic gap between encoder and decoder. Variants of U-Net (such as R2U-Net) have been proposed to address the problem of simple feature extracting blocks by making the network deeper, but it does not deal with the semantic gap problem. On the other hand, another variant UNET++ deals with the semantic gap…
Washington University in St. Louis（圣路易斯华盛顿大学）；University of Illinois at Urbana-Champaign（伊利诺伊大学厄巴纳-香槟分校）；Carle Foundation Hospital（卡尔基金会医院）
It has been advocated that medical imaging systems and reconstruction algorithms should be assessed and optimized by use of objective measures of image quality that quantify the performance of an observer at specific diagnostic tasks. One important source of variability that can significantly limit observer performance is variation in the objects to-be-imaged. This source of variability can be described by stochastic object models (SOMs). A SOM is a generative model that can be employed to establish an ensemble of to-be-imaged objects with prescribed statistical properties. In order to accurat…
A Symmetric Dynamic Learning Framework for Diffeomorphic Medical Image Registration
Xiangtan University（湘潭大学）；University of Strathclyde（思克莱德大学）；Nankai University（南开大学）；Academy of Mathematics and Systems Science, Chinese Academy of Sciences（中国科学院数学与系统科学研究院）；University of Manchester（曼彻斯特大学）
Multiscale Softmax Cross Entropy for Fovea Localization on Color Fundus Photography
Institute of Imaging and Computer Vision, RWTH Aachen, Germany（成像与计算机视觉研究所，RWTH亚琛，德国）；Department of Ophthalmology, RWTH Aachen, Germany（眼科部门，RWTH亚琛，德国）
Deep learning requires large datasets for training (convolutional) networks with millions of parameters. In neuroimaging, there are few open datasets with more than 100 subjects, which makes it difficult to, for example, train a classifier to discriminate controls from diseased persons. Generative adversarial networks (GANs) can be used to synthesize data, but virtually all research is focused on 2D images. In medical imaging, and especially in neuroimaging, most datasets are 3D or 4D. Here we therefore present preliminary results showing that a 3D progressive growing GAN can be used to synthe…
University of Electronic Science and Technology of China（电子科技大学）；Sichuan Cancer Hospital and Institute（四川省肿瘤医院·研究所）
Radiotherapy is the main treatment modality for nasopharynx cancer. Delineation of Gross Target Volume (GTV) from medical images such as CT and MRI images is a prerequisite for radiotherapy. As manual delineation is time-consuming and laborious, automatic segmentation of GTV has a potential to improve this process. Currently, most of the deep learning-based automatic delineation methods of GTV are mainly performed on medical images like CT images. However, it is challenged by the low contrast between the pathology regions and surrounding soft tissues, small target region, and anisotropic resol…
In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and specificity. A medical image could be corrupted by both intrinsic noise, due to the device limitations, and, by extrinsic signal perturbations during image acquisition. Nowadays, CAD deep learning applications pre-process images with image denoising models to reinforce learning and prediction. In this work, an innovative and lightweight deep multiscale convol…
Fair Federated Medical Image Classification Against Quality Shift via Inter-Client Progressive State Matching
School of Electronic Information and Communications, Huazhong University of Science and Technology（华中科技大学电子信息与通信学院）；Lassonde School of Engineering, York University（约克大学拉萨onde工程学院）
Deepwise AI Lab（深睿人工智能实验室）；The University of Hong Kong（香港大学）；Sun Yat-sen University（中山大学）
Recently 3D volumetric organ segmentation attracts much research interest in medical image analysis due to its significance in computer aided diagnosis. This paper aims to address the pancreas segmentation task in 3D computed tomography volumes. We propose a novel end-to-end network, Globally Guided Progressive Fusion Network, as an effective and efficient solution to volumetric segmentation, which involves both global features and complicated 3D geometric information. A progressive fusion network is devised to extract 3D information from a moderate number of neighboring slices and predict a p…
The fusion of multispectral and panchromatic images is always dubbed pansharpening. Most of the available deep learning-based pan-sharpening methods sharpen the multispectral images through a one-step scheme, which strongly depends on the reconstruction ability of the network. However, remote sensing images always have large variations, as a result, these one-step methods are vulnerable to the error accumulation and thus incapable of preserving spatial details as well as the spectral information. In this paper, we propose a novel two-step model for pan-sharpening that sharpens the MS image thr…
Amirkabir University of Technology（阿米尔卡比尔理工大学）；University of Tabriz（大不里士大学）；Deakin University（迪肯大学）
Accurate segmentation of the vertebra is an important prerequisite in various medical applications (E.g. tele surgery) to assist surgeons. Following the successful development of deep neural networks, recent studies have focused on the essential rule of vertebral segmentation. Prior works contain a large number of parameters, and their segmentation is restricted to only one view. Inspired by DoubleU-Net, we propose a novel model named DoubleU-Net++ in which DensNet as feature extractor, special attention module from Convolutional Block Attention on Module (CBAM) and, Pyramid Squeeze Attention …
Deep Neural Networks (DNNs) show a significant impact on medical imaging. One significant problem with adopting DNNs for skin cancer classification is that the class frequencies in the existing datasets are imbalanced. This problem hinders the training of robust and well-generalizing models. Data Augmentation addresses this by using existing data more effectively. However, standard data augmentation implementations are manually designed and produce only limited reasonably alternative data. Instead, Generative Adversarial Networks (GANs) is utilized to generate a much broader set of augmentatio…
