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arXiv 2304.09286cs.RO
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基于AI的智能体用于自动化机器人血管内导丝操控

AI-based Agents for Automated Robotic Endovascular Guidewire Manipulation

Siemens Healthineers(西门子医疗)

Young-Ho Kim, Èric Lluch, Gulsun Mehmet, Florin C. Ghesu, Ankur Kapoor

AI总结:

本文提出一种可扩展学习流程,通过预处理3D CTA图像构建患者特异性血管环境,并利用物理模拟器生成导丝状态数据,将导丝操控问题转化为序列到序列学习问题,训练基于Transformer的AI智能体实现自动化血管内导丝预测控制。

摘要:

血管内导丝操控对于微创临床应用至关重要,例如经皮冠状动脉介入治疗(PCI)、急性缺血性卒中(AIS)的机械取栓技术,以及经颈静脉肝内门体分流术(TIPS)。所有这些手术通常都需要来自三维CTA(计算机断层扫描血管造影)图像的三维血管几何结构。在这些手术过程中,临床医生通常先将导引导管放置在相关血管的开口处,然后操控导丝穿过导管并越过堵塞部位。临床医生仅间歇性地使用X射线透视来观察和引导导管、导丝及其他器械。然而,临床医生仍然依赖X射线透视提供的有限间接观察(即器械的二维局部视图,以及由于辐射限制导致的间歇性更新)来被动控制导丝/导管。由于导丝运动与不同物理特性(如载荷、涂层)以及具有管腔条件的血管几何结构之间存在复杂相互作用,从而形成高度非线性系统,因此对冠状动脉中的导丝操控进行建模和控制仍然具有挑战性。本文介绍了一种可扩展的学习流程,用于训练基于AI的智能体模型,以实现自动化血管内预测性器械控制。首先,我们通过预处理三维CTA图像创建一个可扩展的环境,提供患者特定的三维血管几何结构和冠状动脉中心线。接下来,我们使用基于物理的器械模拟器,从近端施加大量随机生成的运动序列,以生成与每个环境相关的导丝状态。然后,我们将控制问题重新表述为序列到序列的学习问题,其中我们使用基于Transformer的模型,该模型经过训练以处理非线性顺序前向/逆向转移函数。

英文摘要:

Endovascular guidewire manipulation is essential for minimally-invasive clinical applications (Percutaneous Coronary Intervention (PCI), Mechanical thrombectomy techniques for acute ischemic stroke (AIS), or Transjugular intrahepatic portosystemic shunt (TIPS)). All procedures commonly require 3D vessel geometries from 3D CTA (Computed Tomography Angiography) images. During these procedures, the clinician generally places a guiding catheter in the ostium of the relevant vessel and then manipulates a wire through the catheter and across the blockage. The clinician only uses X-ray fluoroscopy intermittently to visualize and guide the catheter, guidewire, and other devices. However, clinicians still passively control guidewires/catheters by relying on limited indirect observation (i.e., 2D partial view of devices, and intermittent updates due to radiation limit) from X-ray fluoroscopy. Modeling and controlling the guidewire manipulation in coronary vessels remains challenging because of the complicated interaction between guidewire motions with different physical properties (i.e., loads, coating) and vessel geometries with lumen conditions resulting in a highly non-linear system. This paper introduces a scalable learning pipeline to train AI-based agent models toward automated endovascular predictive device controls. First, we create a scalable environment by pre-processing 3D CTA images, providing patient-specific 3D vessel geometry and the centerline of the coronary. Next, we apply a large quantity of randomly generated motion sequences from the proximal end to generate wire states associated with each environment using a physics-based device simulator. Then, we reformulate the control problem to a sequence-to-sequence learning problem, in which we use a Transformer-based model, trained to handle non-linear sequential forward/inverse transition functions.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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