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arXiv 2304.06006physics.bio-phcond-mat.soft
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细胞尺度下细丝之间的普适吸引相互作用

A universal attractive interaction between filaments at the cell scale

Anne-Florence Bitbol, Hélène Berthoumieux, Benjamin Spreng, Paulo A. Maia Neto, Serge Reynaud

AI总结:

该研究揭示了细胞尺度下平行细丝间存在一种由卡西米尔效应引起的普适长程吸引作用,其强度可超过热涨落,对细丝束的形成与凝聚有重要意义。

摘要:

肌动蛋白丝和微管在细胞内常形成平行细丝的束状结构。在此,我们揭示了两个平行细丝之间的一种普适吸引相互作用。实际上,浸没在室温或体温下盐水中的介电物体之间的电动力学卡西米尔相互作用包含一个不受溶剂屏蔽的普适贡献,因此是长程的。我们研究了在强德拜屏蔽的盐水中两个平行圆柱体之间的这种相互作用。我们表明,在细胞内的肌动蛋白丝和微管情形下,其强度可大幅超过热涨落的能量尺度。尽管细胞内细丝之间存在多种相互作用,这种普适吸引相互作用应在束形成和凝聚中发挥重要作用。

英文摘要:

Actin filaments and microtubules both often form bundles of parallel filaments within cells. Here, we shed light on a universal attractive interaction between two such parallel filaments. Indeed, the electrodynamic Casimir interaction between dielectric objects immersed in salted water at room or body temperature includes a universal contribution that is unscreened by the solvent and therefore long-ranged. We study this interaction between two parallel cylinders immersed in salted water with strong Debye screening. We show that its magnitude can largely exceed the energy scale of thermal fluctuations in the case of actin filaments and microtubules in cells. While multiple interactions exist between filaments in cells, this universal attractive interaction should thus have an important role, e.g. in bundle formation and cohesion.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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