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arXiv 2302.14218stat.ME
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高维广义线性模型中样本分裂后的去偏Lasso估计与推断

Debiased Lasso After Sample Splitting for Estimation and Inference in High Dimensional Generalized Linear Models

Omar Vazquez, Bin Nan

摘要:

考虑高维广义线性模型的随机样本分裂估计和推断问题,首先使用一个子样本应用套索选择子模型,然后使用剩余的子样本应用去偏套索拟合所选模型。我们证明了,无论是否包含预先设定的回归系数子集,所选子模型在单次分裂后的去偏lasso估计渐近服从正态分布。此外,对于一组预先指定的回归系数,我们表明,基于去偏套索的多重分裂过程可以解决与样本分裂相关的效率损失,并在温和的条件下产生渐近正态估计。我们的模拟结果表明,在估计阶段使用去偏的套索代替标准的极大似然估计可以大大减少所得到的估计的偏差和方差。我们说明了建议的多重分裂去偏套索方法与吸烟数据的中南烟草病例对照研究的分析。

英文摘要:

We consider random sample splitting for estimation and inference in high dimensional generalized linear models, where we first apply the lasso to select a submodel using one subsample and then apply the debiased lasso to fit the selected model using the remaining subsample. We show that, no matter including a prespecified subset of regression coefficients or not, the debiased lasso estimation of the selected submodel after a single splitting follows a normal distribution asymptotically. Furthermore, for a set of prespecified regression coefficients, we show that a multiple splitting procedure based on the debiased lasso can address the loss of efficiency associated with sample splitting and produce asymptotically normal estimates under mild conditions. Our simulation results indicate that using the debiased lasso instead of the standard maximum likelihood estimator in the estimation stage can vastly reduce the bias and variance of the resulting estimates. We illustrate the proposed multiple splitting debiased lasso method with an analysis of the smoking data of the Mid-South Tobacco Case-Control Study.

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