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用于介质调制的可切换信号分子:基础、应用与研究方向

Switchable Signaling Molecules for Media Modulation: Fundamentals, Applications, and Research Directions

Lukas Brand, Maike Scherer, Sebastian Lotter, Teena tom Dieck, Maximilian Schäfer, Andreas Burkovski, Heinrich Sticht, Kathrin Castiglione, Robert Schober

AI总结:

本文综述可切换信号分子的分类与介质调制应用,并以GFPD构建端到端MC系统,首次在闭环管道中实验验证信息传输。

摘要:

尽管分子通信(MC)的一些愿景性应用已经被提出,例如通过协同工作的体内纳米机器实现长期持续健康监测,但在实际实现方面,MC仍处于起步阶段。尤其是长期实验和应用面临诸多问题,例如发射机(TX)处信号分子(SM)的耗尽,以及接收机(RX)处的码间干扰(ISI)。为克服这些实际挑战,一类具有可切换状态的新型SM似乎对未来MC应用颇具前景。在本工作中,我们概述了现有可切换SM,并根据其性质对其进行分类。此外,我们重点说明了可切换SM如何用作介质调制的信息载体。同时,我们给出了一个端到端MC系统的理论和实验结果,该系统采用绿色荧光蛋白变体“Dreiklang”(GFPD)作为可切换SM。我们的实验结果首次表明,在闭环管道系统中利用介质调制成功实现了信息传输。最后,我们讨论了介质调制特有的挑战与机遇。

英文摘要:

Although visionary applications of molecular communication (MC), such as long-term continuous health monitoring by cooperative in-body nanomachines, have been proposed, MC is still in its infancy when it comes to practical implementation. In particular, long-term experiments and applications face issues such as depletion of signaling molecules (SMs) at the transmitter (TX) and inter-symbol interference (ISI) at the receiver (RX). To overcome these practical challenges, a new class of SMs with switchable states seems to be promising for future MC applications. In this work, we provide an overview of existing switchable SMs, and classify them according to their properties. Furthermore, we highlight how switchable SMs can be utilized as information carriers for media modulation. In addition, we present theoretical and experimental results for an end-to-end MC system employing the green fluorescent protein variant "Dreiklang" (GFPD) as switchable SM. Our experimental results show, for the first time, successful information transmission in a closed-loop pipe system using media modulation. Finally, we discuss media modulation specific challenges and opportunities.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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