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arXiv 2302.09446cs.LGstat.ME
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具有隐藏混杂因素的连续时间治疗效果估计

Estimating Treatment Effects in Continuous Time with Hidden Confounders

University of Southern California(南加州大学)

Defu Cao, James Enouen, Yan Liu

摘要:

估计治疗效果在因果推理中起着至关重要的作用,有许多现实世界的应用,如政策分析和决策制定。然而,在存在隐藏混杂因素的情况下,在纵向环境中估计治疗效果仍然是一个极具挑战性的问题。最近,有越来越多的工作试图通过忽略可能存在的隐藏混杂因素,从时间动态观测数据中获得无偏ITE估计。此外,许多现有的工作处理隐藏的混杂因素不适用于连续时间设置。在本文中,我们扩展了工作线,重点是在动态时间设置中存在隐藏的混杂因素的去干扰。我们利用神经微分方程的最新进展,使用随机控制微分方程和Lipschitz约束卷积运算来构建潜在因子模型,以便持续纳入有关正在进行的干预和不规则采样观察的信息。在合成和真实世界数据集上的实验突出了在存在隐藏混杂因素的情况下估计治疗效果的连续时间方法的前景。

英文摘要:

Estimating treatment effects plays a crucial role in causal inference, having many real-world applications like policy analysis and decision making. Nevertheless, estimating treatment effects in the longitudinal setting in the presence of hidden confounders remains an extremely challenging problem. Recently, there is a growing body of work attempting to obtain unbiased ITE estimates from time-dynamic observational data by ignoring the possible existence of hidden confounders. Additionally, many existing works handling hidden confounders are not applicable for continuous-time settings. In this paper, we extend the line of work focusing on deconfounding in the dynamic time setting in the presence of hidden confounders. We leverage recent advancements in neural differential equations to build a latent factor model using a stochastic controlled differential equation and Lipschitz constrained convolutional operation in order to continuously incorporate information about ongoing interventions and irregularly sampled observations. Experiments on both synthetic and real-world datasets highlight the promise of continuous time methods for estimating treatment effects in the presence of hidden confounders.

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