Large annotated datasets are required to train segmentation networks. In medical imaging, it is often difficult, time consuming and expensive to create such datasets, and it may also be difficult to share these datasets with other researchers. Different AI models can today generate very realistic synthetic images, which can potentially be openly shared as they do not belong to specific persons. However, recent work has shown that using synthetic images for training deep networks often leads to worse performance compared to using real images. Here we demonstrate that using synthetic images and annotations from an ensemble of 20 GANs, instead of from a single GAN, increases the Dice score on real test images with 4.7 % to 14.0 % on specific classes.
Tsinghua University（清华大学）；The University of Edinburgh（爱丁堡大学）
Deep learning approaches heavily rely on high-quality human supervision which is nonetheless expensive, time-consuming, and error-prone, especially for image segmentation task. In this paper, we propose a method to automatically synthesize paired photo-realistic images and segmentation masks for the use of training a foreground-background segmentation network. In particular, we learn a generative adversarial network that decomposes an image into foreground and background layers, and avoid trivial decompositions by maximizing mutual information between generated images and latent variables. The…
While GANs have shown success in realistic image generation, the idea of using GANs for other tasks unrelated to synthesis is underexplored. Do GANs learn meaningful structural parts of objects during their attempt to reproduce those objects? In this work, we test this hypothesis and propose a simple and effective approach based on GANs for semantic part segmentation that requires as few as one label example along with an unlabeled dataset. Our key idea is to leverage a trained GAN to extract pixel-wise representation from the input image and use it as feature vectors for a segmentation networ…
Panzhihua University（攀枝花学院）；Tsinghua University（清华大学）；Chinese Institute for Brain Research (CIBR)（中国脑科学研究中心（CIBR））
Recently, unsupervised learning has made impressive progress on various tasks. Despite the dominance of discriminative models, increasing attention is drawn to representations learned by generative models and in particular, Generative Adversarial Networks (GANs). Previous works on the interpretation of GANs reveal that GANs encode semantics in feature maps in a linearly separable form. In this work, we further find that GAN's features can be well clustered with the linear separability assumption. We propose a novel clustering algorithm, named KLiSH, which leverages the linear separability to c…
University of Florence（佛罗伦萨大学）；University of Siena（锡耶纳大学）
Multi-organ segmentation of X-ray images is of fundamental importance for computer aided diagnosis systems. However, the most advanced semantic segmentation methods rely on deep learning and require a huge amount of labeled images, which are rarely available due to both the high cost of human resources and the time required for labeling. In this paper, we present a novel multi-stage generation algorithm based on Generative Adversarial Networks (GANs) that can produce synthetic images along with their semantic labels and can be used for data augmentation. The main feature of the method is that,…
In this paper, we have developed a general-purpose architecture, Vit-Gan, capable of performing most of the image-to-image translation tasks from semantic image segmentation to single image depth perception. This paper is a follow-up paper, an extension of generator-based model [1] in which the obtained results were very promising. This opened the possibility of further improvements with adversarial architecture. We used a unique vision transformers-based generator architecture and Conditional GANs(cGANs) with a Markovian Discriminator (PatchGAN) (https://github.com/YigitGunduc/vit-gan). In th…
University of Bourgogne Franche-Comte（勃艮第-弗朗什孔泰大学）；CASIS inc.（CASIS公司）；University of Sherbrooke（舍布鲁克大学）；University Hospital of Dijon（第戎大学医院）
Generative Adversarial Networks (GANs) have become increasingly powerful, generating mind-blowing photorealistic images that mimic the content of datasets they were trained to replicate. One recurrent theme in medical imaging is whether GANs can also be effective at generating workable medical data as they are for generating realistic RGB images. In this paper, we perform a multi-GAN and multi-application study to gauge the benefits of GANs in medical imaging. We tested various GAN architectures from basic DCGAN to more sophisticated style-based GANs on three medical imaging modalities and org…
Southeast University（东南大学）；Centre de Recherche en Information Biomédicale Sino-Français (CRIBs)（中法生物医学信息研究中心）
3D complete renal structures(CRS) segmentation targets on segmenting the kidneys, tumors, renal arteries and veins in one inference. Once successful, it will provide preoperative plans and intraoperative guidance for laparoscopic partial nephrectomy(LPN), playing a key role in the renal cancer treatment. However, no success has been reported in 3D CRS segmentation due to the complex shapes of renal structures, low contrast and large anatomical variation. In this study, we utilize the adversarial ensemble learning and propose Ensemble Multi-condition GAN(EnMcGAN) for 3D CRS segmentation for the…
Eindhoven University of Technology（埃因霍温理工大学）；Philips Research Laboratories（飞利浦研究实验室）；Philips Healthcare（飞利浦医疗）
There has been considerable interest in the MR physics-based simulation of a database of virtual cardiac MR images for the development of deep-learning analysis networks. However, the employment of such a database is limited or shows suboptimal performance due to the realism gap, missing textures, and the simplified appearance of simulated images. In this work we 1) provide image simulation on virtual XCAT subjects with varying anatomies, and 2) propose sim2real translation network to improve image realism. Our usability experiments suggest that sim2real data exhibits a good potential to augme…
Imperial College London（伦敦帝国学院）；University College London（伦敦大学学院）；KAIST（韩国科学技术院）
Editing facial expressions by only changing what we want is a long-standing research problem in Generative Adversarial Networks (GANs) for image manipulation. Most of the existing methods that rely only on a global generator usually suffer from changing unwanted attributes along with the target attributes. Recently, hierarchical networks that consist of both a global network dealing with the whole image and multiple local networks focusing on local parts are showing success. However, these methods extract local regions by bounding boxes centred around the sparse facial key points which are non…
Segmenting an image into its parts is a frequent preprocess for high-level vision tasks such as image editing. However, annotating masks for supervised training is expensive. Weakly-supervised and unsupervised methods exist, but they depend on the comparison of pairs of images, such as from multi-views, frames of videos, and image augmentation, which limits their applicability. To address this, we propose a GAN-based approach that generates images conditioned on latent masks, thereby alleviating full or weak annotations required in previous approaches. We show that such mask-conditioned image …
Fraunhofer Institute for Digital Medicine MEVIS（弗劳恩霍夫数字医学MEVIS研究所）
Generative networks are fundamentally different in their aim and methods compared to CNNs for classification, segmentation, or object detection. They have initially not been meant to be an image analysis tool, but to produce naturally looking images. The adversarial training paradigm has been proposed to stabilize generative methods, and has proven to be highly successful -- though by no means from the first attempt. This chapter gives a basic introduction into the motivation for Generative Adversarial Networks (GANs) and traces the path of their success by abstracting the basic task and worki…
The Hong Kong University of Science and Technology（香港科技大学）；ByteDance（字节跳动）；The Chinese University of Hong Kong（香港中文大学）；Ant Research（蚂蚁研究院）
Despite the rapid advancement of semantic discovery in the latent space of Generative Adversarial Networks (GANs), existing approaches either are limited to finding global attributes or rely on a number of segmentation masks to identify local attributes. In this work, we present a highly efficient algorithm to factorize the latent semantics learned by GANs concerning an arbitrary image region. Concretely, we revisit the task of local manipulation with pre-trained GANs and formulate region-based semantic discovery as a dual optimization problem. Through an appropriately defined generalized Rayl…
Shandong University of Science and Technology（山东科技大学）；University of Florida（佛罗里达大学）
While most existing segmentation methods usually combined the powerful feature extraction capabilities of CNNs with Conditional Random Fields (CRFs) post-processing, the result always limited by the fault of CRFs . Due to the notoriously slow calculation speeds and poor efficiency of CRFs, in recent years, CRFs post-processing has been gradually eliminated. In this paper, an improved Generative Adversarial Networks (GANs) for image semantic segmentation task (semantic segmentation by GANs, Seg-GAN) is proposed to facilitate further segmentation research. In addition, we introduce Convolutional…
Generative Adversarial Networks (GANs) are an arrange of two neural networks -- the generator and the discriminator -- that are jointly trained to generate artificial data, such as images, from random inputs. The quality of these generated images has recently reached such levels that can often lead both machines and humans into mistaking fake for real examples. However, the process performed by the generator of the GAN has some limitations when we want to condition the network to generate images from subcategories of a specific class. Some recent approaches tackle this \textit{conditional gene…
Generative adversarial networks (GANs) are one of the greatest advances in AI in recent years. With their ability to directly learn the probability distribution of data, and then sample synthetic realistic data. Many applications have emerged, using GANs to solve classical problems in machine learning, such as data augmentation, class unbalance problems, and fair representation learning. In this paper, we analyze and highlight fairness concerns of GANs model. In this regard, we show empirically that GANs models may inherently prefer certain groups during the training process and therefore they…
University of Wisconsin-Madison（威斯康星大学麦迪逊分校）；Adobe Research（奥多比研究院）
We propose a new approach for high resolution semantic image synthesis. It consists of one base image generator and multiple class-specific generators. The base generator generates high quality images based on a segmentation map. To further improve the quality of different objects, we create a bank of Generative Adversarial Networks (GANs) by separately training class-specific models. This has several benefits including -- dedicated weights for each class; centrally aligned data for each model; additional training data from other sources, potential of higher resolution and quality; and easy ma…
Existing conditional image synthesis frameworks generate images based on user inputs in a single modality, such as text, segmentation, sketch, or style reference. They are often unable to leverage multimodal user inputs when available, which reduces their practicality. To address this limitation, we propose the Product-of-Experts Generative Adversarial Networks (PoE-GAN) framework, which can synthesize images conditioned on multiple input modalities or any subset of them, even the empty set. PoE-GAN consists of a product-of-experts generator and a multimodal multiscale projection discriminator…
ADAPT Centre for Digital Content Technology（数字内容技术ADAPT中心）
While cloud/sky image segmentation has extensive real-world applications, a large amount of labelled data is needed to train a highly accurate models to perform the task. Scarcity of such volumes of cloud/sky images with corresponding ground-truth binary maps makes it highly difficult to train such complex image segmentation models. In this paper, we demonstrate the effectiveness of using Generative Adversarial Networks (GANs) to generate data to augment the training set in order to increase the prediction accuracy of image segmentation model. We further present a way to estimate ground-truth …
Bosch Center for Artificial Intelligence（博世人工智能中心）；University of Tübingen（图宾根大学）；University of Bonn（波恩大学）
Joint synthesis of images and segmentation masks with generative adversarial networks (GANs) is promising to reduce the effort needed for collecting image data with pixel-wise annotations. However, to learn high-fidelity image-mask synthesis, existing GAN approaches first need a pre-training phase requiring large amounts of image data, which limits their utilization in restricted image domains. In this work, we take a step to reduce this limitation, introducing the task of one-shot image-mask synthesis. We aim to generate diverse images and their segmentation masks given only a single labelled…
Automatic analysis of spatio-temporal microscopy images is inevitable for state-of-the-art research in the life sciences. Recent developments in deep learning provide powerful tools for automatic analyses of such image data, but heavily depend on the amount and quality of provided training data to perform well. To this end, we developed a new method for realistic generation of synthetic 2D+t microscopy image data of fluorescently labeled cellular nuclei. The method combines spatiotemporal statistical shape models of different cell cycle stages with a conditional GAN to generate time series of …
Recent advances show that Generative Adversarial Networks (GANs) can synthesize images with smooth variations along semantically meaningful latent directions, such as pose, expression, layout, etc. While this indicates that GANs implicitly learn pixel-level correspondences across images, few studies explored how to extract them explicitly. In this work, we introduce Coordinate GAN (CoordGAN), a structure-texture disentangled GAN that learns a dense correspondence map for each generated image. We represent the correspondence maps of different images as warped coordinate frames transformed from …
Recent methods for conditional image generation benefit from dense supervision such as segmentation label maps to achieve high-fidelity. However, it is rarely explored to employ dense supervision for unconditional image generation. Here we explore the efficacy of dense supervision in unconditional generation and find generator feature maps can be an alternative of cost-expensive semantic label maps. From our empirical evidences, we propose a new generator-guided discriminator regularization(GGDR) in which the generator feature maps supervise the discriminator to have rich semantic representati…
Pancreatic Tumor Segmentation as Anomaly Detection in CT Images Using Denoising Diffusion Models
School of Electrical and Computer Engineering, University of Oklahoma（俄克拉荷马大学电气与计算机工程学院）；University of Oklahoma Health Sciences Center（俄克拉荷马大学健康科学中心）；School of Computer Science, University of Oklahoma（俄克拉荷马大学计算机科学学院）
The Chinese University of Hong Kong（香港中文大学）；Ant Research（蚂蚁研究院）；The Hong Kong University of Science and Technology（香港科技大学）；University of California, Los Angeles（加利福尼亚大学洛杉矶分校）
Recent years witness the tremendous success of generative adversarial networks (GANs) in synthesizing photo-realistic images. GAN generator learns to compose realistic images and reproduce the real data distribution. Through that, a hierarchical visual feature with multi-level semantics spontaneously emerges. In this work we investigate that such a generative feature learned from image synthesis exhibits great potentials in solving a wide range of computer vision tasks, including both generative ones and more importantly discriminative ones. We first train an encoder by considering the pretrai…
The recent rise of unsupervised and self-supervised learning has dramatically reduced the dependency on labeled data, providing effective image representations for transfer to downstream vision tasks. Furthermore, recent works employed these representations in a fully unsupervised setup for image classification, reducing the need for human labels on the fine-tuning stage as well. This work demonstrates that large-scale unsupervised models can also perform a more challenging object segmentation task, requiring neither pixel-level nor image-level labeling. Namely, we show that recent unsupervise…
Queen Mary University of London（伦敦玛丽女王大学）；University of Athens（雅典大学）；The Cyprus Institute（塞浦路斯研究所）
Recent advances in the understanding of Generative Adversarial Networks (GANs) have led to remarkable progress in visual editing and synthesis tasks, capitalizing on the rich semantics that are embedded in the latent spaces of pre-trained GANs. However, existing methods are often tailored to specific GAN architectures and are limited to either discovering global semantic directions that do not facilitate localized control, or require some form of supervision through manually provided regions or segmentation masks. In this light, we present an architecture-agnostic approach that jointly discove…
Renault Software Factory（雷诺软件工厂）；CNRS-I3S, Université Côte d’Azur（法国国家科学研究中心-I3S，蔚蓝海岸大学）
This paper proposes two important contributions for conditional Generative Adversarial Networks (cGANs) to improve the wide variety of applications that exploit this architecture. The first main contribution is an analysis of cGANs to show that they are not explicitly conditional. In particular, it will be shown that the discriminator and subsequently the cGAN does not automatically learn the conditionality between inputs. The second contribution is a new method, called a contrario cGAN, that explicitly models conditionality for both parts of the adversarial architecture via a novel a contrari…
Linköping University（林雪平大学）；Center for Medical Image Science and Visualization, Linköping University（林雪平大学医学影像科学与可视化中心）；Sectra AB（Sectra公司）
Insufficient training data is a major bottleneck for most deep learning practices, not least in medical imaging where data is difficult to collect and publicly available datasets are scarce due to ethics and privacy. This work investigates the use of synthetic images, created by generative adversarial networks (GANs), as the only source of training data. We demonstrate that for this application, it is of great importance to make use of multiple GANs to improve the diversity of the generated data, i.e. to sufficiently cover the data distribution. While a single GAN can generate seemingly divers…
