arXivDaily arXiv每日学术速递 周一至周五更新
arXiv 2209.03329stat.MEcs.ITcs.SYeess.SYmath.IT
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最小熵因果推断及其在脑网络分析中的应用

Minimum-entropy causal inference and its application in brain network analysis

Lipeng Ning

摘要:

多元时间序列之间因果关系的识别是数据科学中普遍存在的问题。Granger因果关系测度(GCM)和条件Granger因果关系测度(cGCM)是神经影像学研究中广泛使用的因果推断和有效连接分析的统计方法。GCM和cGCM都具有基于矩阵分解的启发式算法开发的频域公式。这项工作的目标是推广GCM和cGCM措施和他们的频域配方通过使用最小熵(ME)估计的理论框架。所提出的ME估计方法扩展了经典的最小均方误差(MMSE)估计理论的随机过程。它提供了三个配方的cGCM,包括Geweke的原始时域cGCM作为一个特殊的情况。但这三种cGCM的频域公式都不同于以往的方法。基于仿真的实验结果表明,与其他方法相比,所提出的频域CGCM在检测网络连接方面具有增强的灵敏度和特异性。在基于体内功能磁共振成像的示例中,所提出的频域测量cGCM可以显著增强人脑网络的结构连接性和有效连接性之间的一致性。

英文摘要:

Identification of the causal relationship between multivariate time series is a ubiquitous problem in data science. Granger causality measure (GCM) and conditional Granger causality measure (cGCM) are widely used statistical methods for causal inference and effective connectivity analysis in neuroimaging research. Both GCM and cGCM have frequency-domain formulations that are developed based on a heuristic algorithm for matrix decompositions. The goal of this work is to generalize GCM and cGCM measures and their frequency-domain formulations by using a theoretic framework for minimum entropy (ME) estimation. The proposed ME-estimation method extends the classical theory of minimum mean squared error (MMSE) estimation for stochastic processes. It provides three formulations of cGCM that include Geweke's original time-domain cGCM as a special case. But all three frequency-domain formulations of cGCM are different from previous methods. Experimental results based on simulations have shown that one of the proposed frequency-domain cGCM has enhanced sensitivity and specificity in detecting network connections compared to other methods. In an example based on in vivo functional magnetic resonance imaging, the proposed frequency-domain measure cGCM can significantly enhance the consistency between the structural and effective connectivity of human brain networks.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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