We describe a method to extract persistent elements of a dynamic scene from an input video. We represent each scene element as a \emph{Deformable Sprite} consisting of three components: 1) a 2D texture image for the entire video, 2) per-frame masks for the element, and 3) non-rigid deformations that map the texture image into each video frame. The resulting decomposition allows for applications such as consistent video editing. Deformable Sprites are a type of video auto-encoder model that is optimized on individual videos, and does not require training on a large dataset, nor does it rely on pre-trained models. Moreover, our method does not require object masks or other user input, and discovers moving objects of a wider variety than previous work. We evaluate our approach on standard video datasets and show qualitative results on a diverse array of Internet videos. Code and video results can be found at https://deformable-sprites.github.io
Deformable registration is one of the most challenging task in the field of medical image analysis, especially for the alignment between different sequences and modalities. In this paper, a non-rigid registration method is proposed for 3D medical images leveraging unsupervised learning. To the best of our knowledge, this is the first attempt to introduce gradient loss into deep-learning-based registration. The proposed gradient loss is robust across sequences and modals for large deformation. Besides, adversarial learning approach is used to transfer multi-modal similarity to mono-modal simila…
Font generation is a challenging problem especially for some writing systems that consist of a large number of characters and has attracted a lot of attention in recent years. However, existing methods for font generation are often in supervised learning. They require a large number of paired data, which is labor-intensive and expensive to collect. Besides, common image-to-image translation models often define style as the set of textures and colors, which cannot be directly applied to font generation. To address these problems, we propose novel deformable generative networks for unsupervised …
We present GLASS, a method for Global and Local Action-driven Sequence Synthesis. GLASS is a generative model that is trained on video sequences in an unsupervised manner and that can animate an input image at test time. The method learns to segment frames into foreground-background layers and to generate transitions of the foregrounds over time through a global and local action representation. Global actions are explicitly related to 2D shifts, while local actions are instead related to (both geometric and photometric) local deformations. GLASS uses a recurrent neural network to transition be…
Imperial College London（帝国理工学院）；Siemens Healthineers（西门子医疗）
We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key problem in many medical image analysis applications. It is very challenging due to complicated and unknown relationships between different modalities. In this paper, we propose an unsupervised learning approach to reduce the multi-modal registration problem to a mono-modal one through image disentangling. In particular, we decompose images of both modalities …
Shanghai Artificial Intelligence Laboratory（上海人工智能实验室）；East China Normal University（华东师范大学）
Automatic font generation without human experts is a practical and significant problem, especially for some languages that consist of a large number of characters. Existing methods for font generation are often in supervised learning. They require a large number of paired data, which are labor-intensive and expensive to collect. In contrast, common unsupervised image-to-image translation methods are not applicable to font generation, as they often define style as the set of textures and colors. In this work, we propose a robust deformable generative network for unsupervised font generation (ab…
A natural approach to generative modeling of videos is to represent them as a composition of moving objects. Recent works model a set of 2D sprites over a slowly-varying background, but without considering the underlying 3D scene that gives rise to them. We instead propose to model a video as the view seen while moving through a scene with multiple 3D objects and a 3D background. Our model is trained from monocular videos without any supervision, yet learns to generate coherent 3D scenes containing several moving objects. We conduct detailed experiments on two datasets, going beyond the visual…
LIGM, École des Ponts, Univ Gustave Eiffel, CNRS（LIGM，巴黎高科路桥学校，古斯塔夫·埃菲尔大学，法国国家科学研究中心）；Inria and DIENS (ENS-PSL, CNRS, Inria)（法国国家信息与自动化研究所和DIENS（巴黎高等师范学院-巴黎文理研究大学，法国国家科学研究中心，法国国家信息与自动化研究所））；Center for Data Science, New York University（纽约大学数据科学中心）
We present an unsupervised learning framework for decomposing images into layers of automatically discovered object models. Contrary to recent approaches that model image layers with autoencoder networks, we represent them as explicit transformations of a small set of prototypical images. Our model has three main components: (i) a set of object prototypes in the form of learnable images with a transparency channel, which we refer to as sprites; (ii) differentiable parametric functions predicting occlusions and transformation parameters necessary to instantiate the sprites in a given image; (ii…
ShanghaiTech University（上海科技大学）；Tsinghua University（清华大学）；Microsoft Research Asia（微软亚洲研究院）
3D-aware generative models have demonstrated their superb performance to generate 3D neural radiance fields (NeRF) from a collection of monocular 2D images even for topology-varying object categories. However, these methods still lack the capability to separately control the shape and appearance of the objects in the generated radiance fields. In this paper, we propose a generative model for synthesizing radiance fields of topology-varying objects with disentangled shape and appearance variations. Our method generates deformable radiance fields, which builds the dense correspondence between th…
We propose a method to disentangle linear-encoded facial semantics from StyleGAN without external supervision. The method derives from linear regression and sparse representation learning concepts to make the disentangled latent representations easily interpreted as well. We start by coupling StyleGAN with a stabilized 3D deformable facial reconstruction method to decompose single-view GAN generations into multiple semantics. Latent representations are then extracted to capture interpretable facial semantics. In this work, we make it possible to get rid of labels for disentangling meaningful f…
South China University of Technology（华南理工大学）；Rochester Institute of Technology（罗切斯特理工学院）
In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for the accurate alignment of these multi-modal images. However, it remains a very challenging task due to complicated and unknown spatial correspondence between different modalities. In this paper, we propose a novel translation-based unsupervised deformable image registration approach to convert the multi-modal registration problem to a mono-modal one. Specifi…
Image Sciences Institute, University Medical Center Utrecht（乌得勒支大学医学中心图像科学研究所）；Division of Image Processing, Leiden University Medical Center（莱顿大学医学中心图像处理部）
In this work we propose a deep learning network for deformable image registration (DIRNet). The DIRNet consists of a convolutional neural network (ConvNet) regressor, a spatial transformer, and a resampler. The ConvNet analyzes a pair of fixed and moving images and outputs parameters for the spatial transformer, which generates the displacement vector field that enables the resampler to warp the moving image to the fixed image. The DIRNet is trained end-to-end by unsupervised optimization of a similarity metric between input image pairs. A trained DIRNet can be applied to perform registration …
Technion – Israel Institute of Technology（以色列理工学院）
Unsupervised deep-learning (DL) models were recently proposed for deformable image registration tasks. In such models, a neural-network is trained to predict the best deformation field by minimizing some dissimilarity function between the moving and the target images. After training on a dataset without reference deformation fields available, such a model can be used to rapidly predict the deformation field between newly seen moving and target images. Currently, the training process effectively provides a point-estimate of the network weights rather than characterizing their entire posterior d…
We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image registration algorithms to an end-to-end convolutional neural network framework, while maintaining the unsupervised nature of image registration problems. The image-to-image integrated framework can simultaneously learn both image features and transformation matrix for registration. (2) Training with additional data without any label can further improve the registra…
Deformable image registration is a fundamental task in medical image analysis, aiming to establish a dense and non-linear correspondence between a pair of images. Previous deep-learning studies usually employ supervised neural networks to directly learn the spatial transformation from one image to another, requiring task-specific ground-truth registration for model training. Due to the difficulty in collecting precise ground-truth registration, implementation of these supervised methods is practically challenging. Although several unsupervised networks have been recently developed, these metho…
We propose a method to learn 3D deformable object categories from raw single-view images, without external supervision. The method is based on an autoencoder that factors each input image into depth, albedo, viewpoint and illumination. In order to disentangle these components without supervision, we use the fact that many object categories have, at least in principle, a symmetric structure. We show that reasoning about illumination allows us to exploit the underlying object symmetry even if the appearance is not symmetric due to shading. Furthermore, we model objects that are probably, but not…
DPF-Net: Combining Explicit Shape Priors in Deformable Primitive Field for Unsupervised Structural Reconstruction of 3D Objects
National Engineering Laboratory for Brain-inspired Intelligence Technology and Application（脑启发智能技术与应用国家工程实验室）；University of Science and Technology of China（中国科学技术大学）
Image Sciences Institute, University Medical Center Utrecht and Utrecht University（乌得勒支大学医学中心与乌得勒支大学影像科学研究所）；Division of Image Processing of the Leiden University Medical Center（莱顿大学医学中心图像处理部）
Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks (ConvNets), can be used for image registration. Thus far training of ConvNets for registration was supervised using predefined example registrations. However, obtaining example registrations is not trivial. To circumvent the need for predefined examples, and thereby to increase convenience of training ConvNets for image registration, we propose the Deep Learning Im…
We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large data. We define registration as a parametric function, and optimize its parameters given a set of images from a collection of interest. Given a new pair of scans, we can quickly compute a registration field by directly evaluating the function using the learned parameters. We model this function using a convolutional neural network (CNN), and use a spatial transf…
Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images difficult to be used for some applications, for example, generating pseudo-CT for PET-MR attenuation correction. This paper presents a deformation-invariant CycleGAN (DicycleGAN) method using deformable convolutional layers and new cycle-consistency losses. Its robustness dealing with data that suffer from domain-specific nonlinear deformations has been evaluated t…
New York University（纽约大学）；Hyperfine Research（Hyperfine研究公司）；Yale University（耶鲁大学）
Establishing voxelwise semantic correspondence across distinct imaging modalities is a foundational yet formidable computer vision task. Current multi-modality registration techniques maximize hand-crafted inter-domain similarity functions, are limited in modeling nonlinear intensity-relationships and deformations, and may require significant re-engineering or underperform on new tasks, datasets, and domain pairs. This work presents ContraReg, an unsupervised contrastive representation learning approach to multi-modality deformable registration. By projecting learned multi-scale local patch fe…
Unlabeled data learning has attracted considerable attention recently. However, it is still elusive to extract the expected high-level semantic feature with mere unsupervised learning. In the meantime, semi-supervised learning (SSL) demonstrates a promising future in leveraging few samples. In this paper, we combine both to propose an Unsupervised Semantic Aggregation and Deformable Template Matching (USADTM) framework for SSL, which strives to improve the classification performance with few labeled data and then reduce the cost in data annotating. Specifically, unsupervised semantic aggregati…
University of Cambridge（剑桥大学）；Cancer Research UK Cambridge Centre（英国癌症研究中心剑桥中心）；Medical University Vienna（维也纳医科大学）；Cambridge University Hospitals National Health Service (NHS) Foundation Trust（剑桥大学医院国民保健服务基金会信托）；Eindhoven University of Technology（埃因霍温理工大学）；Leiden University（莱顿大学）；University College London（伦敦大学学院）；Cancer Research UK Cambridge Institute（英国癌症研究中心剑桥研究所）
This study investigates the use of the unsupervised deep learning framework VoxelMorph for deformable registration of longitudinal abdominopelvic CT images acquired in patients with bone metastases from breast cancer. The CT images were refined prior to registration by automatically removing the CT table and all other extra-corporeal components. To improve the learning capabilities of VoxelMorph when only a limited amount of training data is available, a novel incremental training strategy is proposed based on simulated deformations of consecutive CT images. In a 4-fold cross-validation scheme…
The Hong Kong University of Science and Technology（香港科技大学）
Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with healthy brain images, most of them would be unable to accurately align images with pathologies due to the absent correspondences in the reference image. In this paper, we propose a deep learning-based deformable registration method that jointly estimates regions with absent correspondence and bidirectional deformation fields. A forward-backward consistency c…
Multi-modality image registration is one of the most underlined processes in medical image analysis. Recently, convolutional neural networks (CNNs) have shown significant potential in deformable registration. However, the lack of voxel-wise ground truth challenges the training of CNNs for an accurate registration. In this work, we propose a cross-modality similarity metric, based on the KL-divergence of image variables, and implement an efficient estimation method using a CNN. This estimation network, referred to as KLDivNet, can be trained unsupervisedly. We then embed the KLDivNet into a reg…
Korea Advanced Institute of Science and Technology（韩国科学技术院）；University of Ulsan College of Medicine（蔚山大学医学院）；Asan Medical Center（峨山医学中心）
Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to its excellent performance in spite of ultra-fast computational time compared to the classical approaches. In this paper, we present a novel unsupervised medical image registration method that trains deep neural network for deformable registration of 3D volumes using a cycle-consistency. Thanks to the cycle consistency, the proposed deep neural networks can t…
Southern Medical University（南方医科大学）；Shenzhen University（深圳大学）
Deformation field estimation is an important and challenging issue in many medical image registration applications. In recent years, deep learning technique has become a promising approach for simplifying registration problems, and has been gradually applied to medical image registration. However, most existing deep learning registrations do not consider the problem that when the receptive field cannot cover the corresponding features in the moving image and the fixed image, it cannot output accurate displacement values. In fact, due to the limitation of the receptive field, the 3 x 3 kernel h…
In this work we present Discrete Attend Infer Repeat (Discrete-AIR), a Recurrent Auto-Encoder with structured latent distributions containing discrete categorical distributions, continuous attribute distributions, and factorised spatial attention. While inspired by the original AIR model andretaining AIR model's capability in identifying objects in an image, Discrete-AIR provides direct interpretability of the latent codes. We show that for Multi-MNIST and a multiple-objects version of dSprites dataset, the Discrete-AIR model needs just one categorical latent variable, one attribute variable (…
Korea Advanced Institute of Science and Technology (KAIST)（韩国科学技术院）
Deformable image registration is one of the fundamental tasks in medical imaging. Classical registration algorithms usually require a high computational cost for iterative optimizations. Although deep-learning-based methods have been developed for fast image registration, it is still challenging to obtain realistic continuous deformations from a moving image to a fixed image with less topological folding problem. To address this, here we present a novel diffusion-model-based image registration method, called DiffuseMorph. DiffuseMorph not only generates synthetic deformed images through revers…
Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences（中国科学院深圳先进技术研究院保罗·C·劳特伯生物医学成像研究中心）；Pengcheng Laboratory（鹏城实验室）；Pazhou Lab（琶洲实验室）；Guizhou Provincial People’s Hospital（贵州省人民医院）
Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration algorithms can still be improved. In this paper, we propose a novel unsupervised learning-based framework to achieve accurate and efficient multi-contrast MR image registrations. Specifically, an end-to-end coarse-to-fine network architecture consisting of affine and deformable transformations is designed to improve the robustness and achieve end-to-end reg…
We present recursive cascaded networks, a general architecture that enables learning deep cascades, for deformable image registration. The proposed architecture is simple in design and can be built on any base network. The moving image is warped successively by each cascade and finally aligned to the fixed image; this procedure is recursive in a way that every cascade learns to perform a progressive deformation for the current warped image. The entire system is end-to-end and jointly trained in an unsupervised manner. In addition, enabled by the recursive architecture, one cascade can be itera…
University of Oxford（牛津大学）；Institute of Biomedical Engineering（生物医学工程研究所）
Recent successes in deep learning based deformable image registration (DIR) methods have demonstrated that complex deformation can be learnt directly from data while reducing computation time when compared to traditional methods. However, the reliance on fully linear convolutional layers imposes a uniform sampling of pixel/voxel locations which ultimately limits their performance. To address this problem, we propose a novel approach of learning a continuous warp of the source image. Here, the required deformation vector fields are obtained from a concatenated linear and non-linear convolution …
Unsupervised Deformable Image Registration with Local-Global Attention and Image Decomposition
Institute of Medical Technology, Peking University Health Science Center（北京大学医学部医学技术研究所）；National Institute of Health Data Science, Peking University（北京大学国家健康数据科学研究院）；Department of Radiology, Peking University Third Hospital（北京大学第三医院放射科）；Department of Pediatrics, Peking University First Hospital（北京大学第一医院儿科）；Pediatric Epilepsy Center, Peking University First Hospital（北京大学第一医院儿童癫痫中心）；School of Biological Science and Medical Engineering, Southeast University（东南大学生物科学与医学工程学院）；Institute for Artificial Intelligence, Peking University（北京大学人工智能研究院）
NYU（纽约大学）；NVidia（英伟达）；Technical University of Berlin（柏林工业大学）；Google（谷歌）
We propose a self-supervised framework to learn scene representations from video that are automatically delineated into background, characters, and their animations. Our method capitalizes on moving characters being equivariant with respect to their transformation across frames and the background being constant with respect to that same transformation. After training, we can manipulate image encodings in real time to create unseen combinations of the delineated components. As far as we know, we are the first method to perform unsupervised extraction and synthesis of interpretable background, c…
Pixel-wise Agricultural Image Time Series Classification: Comparisons and a Deformable Prototype-based Approach
LIGM, Ecole des Ponts, Univ Gustave Eiffel, CNRS（LIGM实验室、巴黎路桥学校、古斯塔夫·埃菲尔大学、法国国家科学研究中心）；Inria Paris（巴黎信息与自动化研究所）；Ecole normale superieure (ENS-PSL, CNRS, Inria)（巴黎高等师范学院（PSL大学成员）、法国国家科学研究中心、法国信息与自动化研究所）；Center for Data Science, New York University（纽约大学数据科学中心）
Korea Advanced Institute of Science and Technology（韩国科学技术院）；The Catholic University of Korea（韩国加图立大学）；University of Ulsan College of Medicine（蔚山大学医学院）；Asan Medical Center（峨山医疗中心）；Korea Automotive Technology Institute（韩国汽车技术研究院）
Image registration is a fundamental task in medical image analysis. Recently, deep learning based image registration methods have been extensively investigated due to their excellent performance despite the ultra-fast computational time. However, the existing deep learning methods still have limitation in the preservation of original topology during the deformation with registration vector fields. To address this issues, here we present a cycle-consistent deformable image registration. The cycle consistency enhances image registration performance by providing an implicit regularization to pres…
Unsupervised Deformable Image Registration with Structural Nonparametric Smoothing
Cornell University（康奈尔大学）；Hunan University（湖南大学）；University of Pennsylvania（宾夕法尼亚大学）；Johns Hopkins University（约翰霍普金斯大学）；Shanghai Jiao Tong University（上海交通大学）；University of Birmingham（伯明翰大学）；University of Manchester（曼彻斯特大学）
Ryerson University（瑞尔森大学）；University of Toronto（多伦多大学）；Institute for Biomedical Engineering, Science and Technology (iBEST)（生物医学工程、科学与技术研究所（iBEST））
We propose FlowReg, a deep learning-based framework for unsupervised image registration for neuroimaging applications. The system is composed of two architectures that are trained sequentially: FlowReg-A which affinely corrects for gross differences between moving and fixed volumes in 3D followed by FlowReg-O which performs pixel-wise deformations on a slice-by-slice basis for fine tuning in 2D. The affine network regresses the 3D affine matrix based on a correlation loss function that enforces global similarity. The deformable network operates on 2D image slices based on the optical flow netw…
Unsupervised Analysis of Alzheimer's Disease Signatures using 3D Deformable Autoencoders
Technical University of Munich（慕尼黑工业大学）；Helmholtz AI（亥姆霍兹人工智能研究所）；School of Biomedical Engineering and Imaging Sciences, King’s College London（伦敦国王学院生物医学工程与影像科学学院）；Klinikum Rechts der Isar（慕尼黑右岸医院）；Imperial College London（伦敦帝国学院）
Johns Hopkins Medical Institutes（约翰霍普金斯医学研究所）；Johns Hopkins University（约翰霍普金斯大学）
Objectives: Computerized phantoms play an essential role in various applications of medical imaging research. Although the existing computerized phantoms can model anatomical variations through organ and phantom scaling, this does not provide a way to fully reproduce anatomical variations seen in humans. However, having a population of phantoms that models the variations in patient anatomy and, in nuclear medicine, uptake realization is essential for comprehensive validation and training. In this work, we present a novel image registration method for creating highly anatomically detailed anthr…
Chengdu University of Information Technology（成都信息工程大学）；Keya Medical（科亚医疗）；University at Buffalo, SUNY（纽约州立大学布法罗分校）
Large deformations of organs, caused by diverse shapes and nonlinear shape changes, pose a significant challenge for medical image registration. Traditional registration methods need to iteratively optimize an objective function via a specific deformation model along with meticulous parameter tuning, but which have limited capabilities in registering images with large deformations. While deep learning-based methods can learn the complex mapping from input images to their respective deformation field, it is regression-based and is prone to be stuck at local minima, particularly when large defor…
UT Austin（德克萨斯大学奥斯汀分校）；MIT（麻省理工学院）；Hohai University（河海大学）
This paper introduces an unsupervised loss for training parametric deformation shape generators. The key idea is to enforce the preservation of local rigidity among the generated shapes. Our approach builds on an approximation of the as-rigid-as possible (or ARAP) deformation energy. We show how to develop the unsupervised loss via a spectral decomposition of the Hessian of the ARAP energy. Our loss nicely decouples pose and shape variations through a robust norm. The loss admits simple closed-form expressions. It is easy to train and can be plugged into any standard generation models, e.g., v…
ETH Zurich（苏黎世联邦理工学院）；University of Amsterdam（阿姆斯特丹大学）；KU Leuven（鲁汶大学）
Monocular depth reconstruction of complex and dynamic scenes is a highly challenging problem. While for rigid scenes learning-based methods have been offering promising results even in unsupervised cases, there exists little to no literature addressing the same for dynamic and deformable scenes. In this work, we present an unsupervised monocular framework for dense depth estimation of dynamic scenes, which jointly reconstructs rigid and non-rigid parts without explicitly modelling the camera motion. Using dense correspondences, we derive a training objective that aims to opportunistically pres…
Unsupervised Pelage Pattern Unwrapping for Animal Re-identification
Computer Vision and Pattern Recognition Laboratory (CVPRL)（计算机视觉与模式识别实验室）；Lappeenranta-Lahti University of Technology LUT（拉佩恩拉-拉赫蒂理工大学）；Faculty of Information Technology Brno University of Technology (BUT)（信息科技学院布拉格技术大学）；Rensselaer Polytechnic Institute (RPI)（伦塞拉尔理工学院）
University of Electronic Science and Technology of China（电子科技大学）；Alibaba Group（阿里巴巴集团）
Given a source image and a driving video depicting the same object type, the motion transfer task aims to generate a video by learning the motion from the driving video while preserving the appearance from the source image. In this paper, we propose a novel structure-aware motion modeling approach, the deformable anchor model (DAM), which can automatically discover the motion structure of arbitrary objects without leveraging their prior structure information. Specifically, inspired by the known deformable part model (DPM), our DAM introduces two types of anchors or keypoints: i) a number of mo…
Snap Inc.（Snap公司）；University of Trento（特伦托大学）；KAUST（阿卜杜拉国王科技大学）
We propose a novel approach for unsupervised 3D animation of non-rigid deformable objects. Our method learns the 3D structure and dynamics of objects solely from single-view RGB videos, and can decompose them into semantically meaningful parts that can be tracked and animated. Using a 3D autodecoder framework, paired with a keypoint estimator via a differentiable PnP algorithm, our model learns the underlying object geometry and parts decomposition in an entirely unsupervised manner. This allows it to perform 3D segmentation, 3D keypoint estimation, novel view synthesis, and animation. We prim…
