Domain Adaptation of Automated Treatment Planning from Computed Tomography to Magnetic Resonance
University of Toronto（多伦多大学）；Techna Institute, University Health Network（大学健康网络泰克纳研究所）；Princess Margaret Cancer Center（玛格丽特公主癌症中心）；Peter Munk Cardiac Center, University Health Network（大学健康网络彼得·蒙克心脏中心）；Joint Department of Medical Imaging, University Health Network（大学健康网络医学影像联合部）；Vector Institute（矢量研究所）
Aly Khalifa, Jeff Winter, Inmaculada Navarro, Chris McIntosh, Thomas G. Purdie
Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning workflows, we sought to determine if an ML based treatment planning model, trained on computed tomography (CT) imaging, could be applied to MR through domain adaptation. Methods: In this study, MR and CT imaging was collected from 55 prostate cancer patients treated on an MR linear accelerator. ML based plans were generated for each patient on both CT and MR imaging using a commercially available model in RayStation 8B. The dose distributions and acceptance rates of MR and CT based plans were compared using institutional dose-volume evaluation criteria. The dosimetric differences between MR and CT plans were further decomposed into setup, cohort, and imaging domain components. Results: MR plans were highly acceptable, meeting 93.1% of all evaluation criteria compared to 96.3% of CT plans, with dose equivalence for all evaluation criteria except for the bladder wall, penile bulb, small and large bowel, and one rectum wall criteria (p<0.05). Changing the input imaging modality (domain component) only accounted for about half of the dosimetric differences observed between MR and CT plans. Anatomical differences between the ML training set and the MR linac cohort (cohort component) were also a significant contributor. Significance: We were able to create highly acceptable MR based treatment plans using a CT-trained ML model for treatment planning, although clinically significant dose deviations from the CT based plans were observed.
Test-Time Adaptation in Optical Coherence Tomography Using Trajectory-Aligned Time-Independent Flow
Institute of Artificial Intelligence, Center for Medical Data Science, Medical University of Vienna, Austria（人工智能研究所、医学数据科学中心、维也纳医学大学，奥地利）；Comprehensive Center for Artificial Intelligence in Medicine, Medical University of Vienna, Austria（医学人工智能综合中心、维也纳医学大学，奥地利）；Department of Ophthalmology and Optometry, Medical University of Vienna, Austria（眼科与视光学部、维也纳医学大学，奥地利）；Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Austria（眼科图像分析实验室、维也纳医学大学，奥地利）
PET-Adapter: Test-Time Domain Adaptation for Full and Limited-Angle PET Image Reconstruction
Institute of Imaging and Computer Vision, RWTH Aachen University, Germany（成像与计算机视觉研究所，亚琛工业大学，德国）；Machine Learning for Medical Data, Heinrich Heine University Düsseldorf, Germany（医学数据机器学习，杜伊斯堡-艾森大学，德国）
Noise transfer for unsupervised domain adaptation of retinal OCT images
Technical University of Munich（慕尼黑工业大学）；Institute of AI for Health, Helmholtz Munich（亥姆霍兹慕尼黑中心健康人工智能研究所）；Munich School for Data Science（慕尼黑数据科学学院）；Institute of Computational Biology, Helmholtz Munich（亥姆霍兹慕尼黑中心计算生物学研究所）；Ludwig-Maximilians-University（路德维希-马克西米利安大学）
COBRA2026: a large-scale multicenter pelvic cone-beam computed tomography projection dataset
University of Bern（伯尔尼大学）；LMU Munich（慕尼黑大学）；University Hospital of Cologne（科隆大学医院）；University Medical Center Utrecht（乌得勒支大学医学中心）；Medical University of Graz（格拉茨医科大学）；Lund University（隆德大学）；Skåne University Hospital（斯卡奈大学医院）
