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arXiv 2203.02446cs.AIcs.LG
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AutoMap:用于临床预测模型部署的自动医疗代码映射

AutoMap: Automatic Medical Code Mapping for Clinical Prediction Model Deployment

University of Illinois at Urbana-Champaign(伊利诺伊大学厄巴纳-香槟分校);Amplitude(Amplitude公司);IQVIA(艾昆纬);Northwestern University(西北大学)

Zhenbang Wu, Cao Xiao, Lucas M Glass, David M Liebovitz, Jimeng Sun

摘要:

给定一个基于源站点数据训练的深度学习模型,如何将模型自动部署到目标医院?如何适应不同医院的异构医疗编码系统?标准方法依赖于现有的医疗代码映射工具,其具有显著的实际局限性。为了解决这个问题,我们提出了AutoMap,以粗到细的方式自动映射不同EHR系统之间的医疗代码:(1)本体级对齐:我们利用本体结构来学习源和目标医疗编码系统之间的粗对齐;(2)代码级细化:我们使用师生框架在细粒度代码级细化下游任务的对齐。我们使用几个深度学习模型和两个真实世界的EHR数据集:eICU和MIMIC-III来评估AutoMap。结果表明,AutoMap在死亡率预测方面实现了高达3.9%(AUC-ROC)和8.7%(AUC-PR)的相对改善,在住院时间估计方面实现了高达4.7%(AUC-ROC)和3.7%(F1)的相对改善。此外,我们表明,AutoMap可以提供跨编码系统的准确映射。最后,我们证明了AutoMap可以适应两个具有挑战性的场景:(1)完全不同的编码系统之间的映射和(2)完全不同的医院之间的映射。

英文摘要:

Given a deep learning model trained on data from a source site, how to deploy the model to a target hospital automatically? How to accommodate heterogeneous medical coding systems across different hospitals? Standard approaches rely on existing medical code mapping tools, which have significant practical limitations. To tackle this problem, we propose AutoMap to automatically map the medical codes across different EHR systems in a coarse-to-fine manner: (1) Ontology-level Alignment: We leverage the ontology structure to learn a coarse alignment between the source and target medical coding systems; (2) Code-level Refinement: We refine the alignment at a fine-grained code level for the downstream tasks using a teacher-student framework. We evaluate AutoMap using several deep learning models with two real-world EHR datasets: eICU and MIMIC-III. Results show that AutoMap achieves relative improvements up to 3.9% (AUC-ROC) and 8.7% (AUC-PR) for mortality prediction, and up to 4.7% (AUC-ROC) and 3.7% (F1) for length-of-stay estimation. Further, we show that AutoMap can provide accurate mapping across coding systems. Lastly, we demonstrate that AutoMap can adapt to the two challenging scenarios: (1) mapping between completely different coding systems and (2) between completely different hospitals.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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