利用浅景深的虚拟光学切片和层析成像方法
A method for virtual optical sectioning and tomography utilizing shallow depth of field
摘要：
提出了一种从平面透射图像中重建物体内部结构的高分辨率三维重建方法。原则上，所描述的方法可以与任何形式的辐射或物质波一起使用，只要景深小于样品的厚度。阐述了该方法的物理光学基础，并详细介绍了重建算法。一个模拟的例子演示了应用该方法的三维电子透射成像的纳米粒子下现实的辐射剂量和空间分辨率的限制。可以设想，该方法可以应用于高分辨率透射电子显微镜、软X射线显微镜、超声成像等领域。
英文摘要：
A method is proposed for high-resolution, three-dimensional reconstruction of internal structure of objects from planar transmission images. The described approach can be used with any form of radiation or matter waves, in principle, provided that the depth of field is smaller than the thickness of the sample. The physical optics basis for the method is elucidated and the reconstruction algorithm is presented in detail. A simulated example demonstrates an application of the method to three-dimensional electron transmission imaging of a nanoparticle under realistic radiation dose and spatial resolution constraints. It is envisaged that the method can be applicable in high-resolution transmission electron microscopy, soft X-ray microscopy, ultrasound imaging and other areas.
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