Improving Estimation Efficiency via Regression-Adjustment in Covariate-Adaptive Randomizations with Imperfect Compliance
Liang Jiang, Oliver B. Linton, Haihan Tang, Yichong Zhang
备注:
The paper is previously circulated under the title "Regression Adjustments under Covariate-Adaptive Randomizations with Imperfect Compliance." 94 pages
We investigate how to improve efficiency using regression adjustments with covariates in covariate-adaptive randomizations (CARs) with imperfect subject compliance. Our regression-adjusted estimators, which are based on the doubly robust moment for local average treatment effects, are consistent and asymptotically normal even with heterogeneous probability of assignment and misspecified regression adjustments. We propose an optimal but potentially misspecified linear adjustment and its further improvement via a nonlinear adjustment, both of which lead to more efficient estimators than the one without adjustments. We also provide conditions for nonparametric and regularized adjustments to achieve the semiparametric efficiency bound under CARs.
Harvard University(哈佛大学);KU Leuven(鲁汶大学);IMT School for Advanced Studies(IMT高等研究院)
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College of Computer Science and Technology, Zhejiang University(浙江大学计算机科学与技术学院);Emory University(埃默里大学);Gaoling School of Artificial Intelligence, Renmin University of China(中国人民大学高瓴人工智能学院);Carnegie Mellon University(卡内基梅隆大学)