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arXiv 2103.16532cond-mat.soft
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用活性粒子模拟微量吸管的抽吸

Modelling Micropipette Aspiration with Active Particles

G. Ourique, E. F. Teixeira, L. G. Brunnet

摘要:

细胞动力学特性的研究对于更好地理解几个生理过程是必不可少的。这些性质与通过物理应力实验获得的细胞机械参数直接相关。微量吸液管抽吸试验已被证明是一种准确和可控的工具,可对细胞施加物理应力。在这项工作中,我们探讨了二维细胞的数值模拟,使用一个积极的多粒子环提交给微管抽吸。我们将模拟参数与实验数据相关联,并获得了输入参数和实验中可以测量的弹性参数的完整映射。

英文摘要:

The study of cells' dynamical properties is essential to a better understanding of several physiological processes. These properties are directly associated with cells' mechanical parameters experimentally achieved through physical stress. The micropipette aspiration essay has proven an accurate and controllable tool to apply physical stress to the cell. In this work, we explore the numerical modeling of two-dimensional cells using an active multi-particle ring submitted to micropipette aspiration. We correlate simulation parameters with experimental data and obtain a complete map of the input parameters and the resulting elastic parameters that could be measured in experiments.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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