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arXiv 2102.08284math.DSnlin.CDq-bio.PE
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控制传染病:季节性疫苗接种策略的决定性阶段效应

Controlling infectious diseases: the decisive phase effect on a seasonal vaccination strategy

Jorge Duarte, Cristina Januário, Nuno Martins, Jesús Seoane, Miguel AF Sanjuán

摘要:

流行病学系统的研究产生了浓厚的兴趣,探索由季节性变化的接触率驱动的常见传染病的动态复杂性。数学模型和实地观察表明,在季节变化下,一些地方性传染病的发病率波动剧烈,在没有特定疫苗接种计划的情况下,动态往往表现为混沌振荡。事实上,混沌行为的存在已经在文献中被精确地描述为经典的季节性强迫传染病模型的动力学中的一个显著特征。然而,在流行病学的背景下,混乱通常被认为是一种与传染病的不可预测性相关的不良现象。因此,将混沌运动转换为规则运动的问题变得特别相关。在这篇文章中,我们考虑相位控制技术应用于季节性强迫SIR流行病模型,以抑制混沌。有趣的是,这种控制混沌的方法具有明确的意义,即对季节性疫苗接种策略的弱扰动。数值模拟表明,两个周期力--接触率和疫苗接种--之间的相位差在控制混沌中起着非常重要的作用。

英文摘要:

The study of epidemiological systems has generated deep interest in exploring the dynamical complexity of common infectious diseases driven by seasonally varying contact rates. Mathematical modeling and field observations have shown that, under seasonal variation, the incidence rates of some endemic infectious diseases fluctuate dramatically and the dynamics is often characterized by chaotic oscillations in the absence of specific vaccination programs. In fact, the existence of chaotic behavior has been precisely stated in the literature as a noticeable feature in the dynamics of the classical Susceptible-Infected-Recovered (SIR) seasonally forced epidemic model. However, in the context of epidemiology, chaos is often regarded as an undesirable phenomenon associated with the unpredictability of infectious diseases. As a consequence, the problem of converting chaotic motions into regular motions becomes particularly relevant. In this article, we consider the phase control technique applied to the seasonally forced SIR epidemic model to suppress chaos. Interestingly, this method of controlling chaos takes on a clear meaning as a weak perturbation on a seasonal vaccination strategy. Numerical simulations show that the phase difference between the two periodic forces - contact rate and vaccination - plays a very important role in controlling chaos.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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