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arXiv 2102.07442cond-mat.softphysics.bio-ph
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微滴的自组织和主动极化形变

Self-organization and shape change by active polarization in nematic droplets

Fabian Jan Schwarzendahl, Pierre Ronceray, Kimberly L. Weirich, Kinjal Dasbiswas

摘要:

细胞内发生的积极力量可以驱动涉及自发组织和形状变化的关键生物过程,如细胞分裂。最近在体外实验的细胞骨架丝和电机,自组织和分裂的微滴的动机,我们提出了一个最小的流体动力学模型,结合了非平衡动力学的电机丝的相互作用与平衡微相分离。马达在液滴内组织,并将细丝结构化成极化的星状缺陷。在大的运动活动中,它们甚至可以使液滴变形或分裂,或形成多星状液滴链。我们预测的相图概括了这些实验观察到的形状。

英文摘要:

Active forces occurring within cells can drive crucial biological processes that involve spontaneous organization and shape change, such as cell division. Motivated by recent in vitro experiments of nematic droplets of cytoskeletal filaments and motors that self-organize and divide, we present a minimal hydrodynamic model that combines the nonequilibrium kinetics of motor-filament interactions with equilibrium nematic phase separation. The motors organize within droplets and structure filaments into polarized aster defects. At large motor activity, they can even deform or divide the droplet, or form multi-aster chains of droplets. Our predicted phase diagram recapitulates these experimentally observed shapes.

机构、总结、中文摘要均由AI分析而来,可能存在错误,请以论文正文为准。

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