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arXiv 2102.06240physics.acc-phphysics.med-ph
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MedAustron质子束低粒子通量调试

Commissioning of low particle flux for proton beams at MedAustron

Felix Ulrich-Pur, Laurids Adler, Thomas Bergauer, Alexander Burker, Andrea De Franco, Greta Guidoboni, Albert Hirtl, Christian Irmler, Stefanie Kaser, Sebastian… 展开作者

Felix Ulrich-Pur, Laurids Adler, Thomas Bergauer, Alexander Burker, Andrea De Franco, Greta Guidoboni, Albert Hirtl, Christian Irmler, Stefanie Kaser, Sebastian Nowak, Florian Pitters, Mauro Pivi, Dale Prokopovich, Claus Schmitzer, Alexander Wastl

摘要:

MedAustron是一家位于奥地利维也纳新城的同步加速器粒子治疗中心。它设有三个用于粒子治疗的辐照室,其中能量高达252.7 MeV的质子束和高达402.8 MeV/u的碳离子可用于癌症治疗。除了治疗室外,MedAustron还拥有一条专门用于非临床研究(NCR)的独特光束线。该研究束线还用于高达800 MeV的质子能量,而可用的碳离子能量对应于临床治疗室中可用的能量。根据粒子治疗的要求,所有辐照室提供的质子粒子率高达10^9粒子/秒,碳离子粒子率高达10^7粒子/秒。然而,出于研究目的,需要较低的粒子通量,因此为NCR束线进行了调试。对于能量低于252.7 MeV的7个质子,建立了3种粒子通量设置,粒子速率范围为~2.4x10^3粒子/s ~~5.2x10^6粒子/s。除了颗粒率之外,还测量了这些设置的光斑尺寸和光束能量。此外,还调试了三个用于800 MeV质子的低通量设置,粒子速率范围从~2x10^3粒子/秒到~1.3x10^6粒子/秒。由于已调试的低通量设置处于远低于可用标准束流诊断极限的状态,因此在这些新的操作条件下设置束流完全依赖于使用外部探测器。此外,不使用标准束轮廓监测器的束位置测量为基础的对齐进行800 MeV质子。

英文摘要:

MedAustron is a synchrotron-based particle therapy centre located in Wiener Neustadt, Austria. It features three irradiation rooms for particle therapy, where proton beams with energies up to 252.7 MeV and carbon ions of up to 402.8 MeV/u are available for cancer treatment. In addition to the treatment rooms, MedAustron features a unique beamline exclusively for non-clinical research (NCR). This research beamline is also commissioned for proton energies up to 800 MeV, while available carbon ion energies correspond to the ones available in the clinical treatment rooms. Based on the requirements for particle therapy, all irradiation rooms offer particle rates of up to 10^9 particles/s for protons and 10^7 particles/s for carbon ions. However, for research purposes, lower particle fluxes are required and were therefore commissioned for the NCR beamline. Three particle flux settings with particle rates ranging from ~2.4x10^3 particles/s to ~5.2x10^6 particles/s were established for seven proton energies below 252.7 MeV. In addition to the particle rate, the spot sizes and beam energies were measured for these settings. Furthermore, three low flux settings for 800 MeV protons with particle rates ranging from ~2x10^3 particles/s to ~1.3x10^6 particles/s were commissioned. Since the commissioned low flux settings are in a regime well below the limits of the available standard beam diagnostics, setting up the beam under these new operational conditions entirely relied on the use of external detectors. Furthermore, a beam position measurement based alignment without using the standard beam profile monitors was performed for 800 MeV protons.

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