TEMImageNet Training Library and AtomSegNet Deep-Learning Models for High-Precision Atom Segmentation, Localization, Denoising, and Super-Resolution Processing of Atomic-Resolution Images
Brookhaven National Laboratory（布鲁克海文国家实验室）；University of California, Irvine（加利福尼亚大学尔湾分校）
Atom segmentation and localization, noise reduction and deblurring of atomic-resolution scanning transmission electron microscopy (STEM) images with high precision and robustness is a challenging task. Although several conventional algorithms, such has thresholding, edge detection and clustering, can achieve reasonable performance in some predefined sceneries, they tend to fail when interferences from the background are strong and unpredictable. Particularly, for atomic-resolution STEM images, so far there is no well-established algorithm that is robust enough to segment or detect all atomic columns when there is large thickness variation in a recorded image. Herein, we report the development of a training library and a deep learning method that can perform robust and precise atom segmentation, localization, denoising, and super-resolution processing of experimental images. Despite using simulated images as training datasets, the deep-learning model can self-adapt to experimental STEM images and shows outstanding performance in atom detection and localization in challenging contrast conditions and the precision consistently outperforms the state-of-the-art two-dimensional Gaussian fit method. Taking a step further, we have deployed our deep-learning models to a desktop app with a graphical user interface and the app is free and open-source. We have also built a TEM ImageNet project website for easy browsing and downloading of the training data.
Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the DNN results from low-dose inputs are also shown to be comparable to their high-dose counterparts. However, these metrics do not reveal if the DNN results preserve the visibility of subtle lesions or if they alter the CT image properties such as the noise texture. Accordingly, in this work, we seek to examine the image quality of the DNN results from a holis…
Self-supervised frameworks that learn denoising models with merely individual noisy images have shown strong capability and promising performance in various image denoising tasks. Existing self-supervised denoising frameworks are mostly built upon the same theoretical foundation, where the denoising models are required to be J-invariant. However, our analyses indicate that the current theory and the J-invariance may lead to denoising models with reduced performance. In this work, we introduce Noise2Same, a novel self-supervised denoising framework. In Noise2Same, a new self-supervised loss is …
Image super-resolution and denoising are two important tasks in image processing that can lead to improvement in image quality. Image super-resolution is the task of mapping a low resolution image to a high resolution image whereas denoising is the task of learning a clean image from a noisy input. We propose and train a single deep learning network that we term as SuRDCNN (super-resolution and denoising convolutional neural network), to perform these two tasks simultaneously . Our model nearly replicates the architecture of existing state-of-the-art deep learning models for super-resolution a…
Recently, Self-supervised learning methods able to perform image denoising without ground truth labels have been proposed. These methods create low-quality images by adding random or Gaussian noise to images and then train a model for denoising. Ideally, it would be beneficial if one can generate high-quality CT images with only a few training samples via self-supervision. However, the performance of CT denoising is generally limited due to the complexity of CT noise. To address this problem, we propose a novel self-supervised learning-based CT denoising method. In particular, we train pre-tra…
Sungkyunkwan University（成均馆大学）；Ulsan National Institute of Science and Technology（蔚山科学技术院）；Shanghai Jiao Tong University（上海交通大学）；Seoul National University（首尔国立大学）
Regression that predicts continuous quantity is a central part of applications using computational imaging and computer vision technologies. Yet, studying and understanding self-supervised learning for regression tasks - except for a particular regression task, image denoising - have lagged behind. This paper proposes a general self-supervised regression learning (SSRL) framework that enables learning regression neural networks with only input data (but without ground-truth target data), by using a designable pseudo-predictor that encapsulates domain knowledge of a specific application. The pa…
School of Computer and Communication Sciences, EPFL（洛桑联邦理工学院计算机与通信科学学院）
Super-resolution and denoising are ill-posed yet fundamental image restoration tasks. In blind settings, the degradation kernel or the noise level are unknown. This makes restoration even more challenging, notably for learning-based methods, as they tend to overfit to the degradation seen during training. We present an analysis, in the frequency domain, of degradation-kernel overfitting in super-resolution and introduce a conditional learning perspective that extends to both super-resolution and denoising. Building on our formulation, we propose a stochastic frequency masking of images used in…
In this paper, we propose a novel and efficient CNN-based framework that leverages local and global context information for image denoising. Due to the limitations of convolution itself, the CNN-based method is generally unable to construct an effective and structured global feature representation, usually called the long-distance dependencies in the Transformer-based method. To tackle this problem, we introduce the matrix decomposition module(MD) in the network to establish the global context feature, comparable to the Transformer based method performance. Inspired by the design of multi-stag…
Positive2Negative: Breaking the Information-Lossy Barrier in Self-Supervised Single Image Denoising
School of Computer Science and Technology, Beijing Institute of Technology（北京理工大学计算机科学与技术学院）；School of Artificial Intelligence, Beijing Normal University（北京师范大学人工智能学院）；Aerospace Information Research Institute, Chinese Academy of Sciences（中国科学院空天信息创新研究院）
The Chinese University of Hong Kong（香港中文大学）；SenseTime Research（商汤科技研究院）
The lack of large-scale noisy-clean image pairs restricts supervised denoising methods' deployment in actual applications. While existing unsupervised methods are able to learn image denoising without ground-truth clean images, they either show poor performance or work under impractical settings (e.g., paired noisy images). In this paper, we present a practical unsupervised image denoising method to achieve state-of-the-art denoising performance. Our method only requires single noisy images and a noise model, which is easily accessible in practical raw image denoising. It performs two steps it…
Classical image denoising methods utilize the non-local self-similarity principle to effectively recover image content from noisy images. Current state-of-the-art methods use deep convolutional neural networks (CNNs) to effectively learn the mapping from noisy to clean images. Deep denoising CNNs manifest a high learning capacity and integrate non-local information owing to the large receptive field yielded by numerous cascade of hidden layers. However, deep networks are also computationally complex and require large data for training. To address these issues, this study draws the focus on the…
With the advent of recent advances in unsupervised learning, efficient training of a deep network for image denoising without pairs of noisy and clean images has become feasible. However, most current unsupervised denoising methods are built on the assumption of zero-mean noise under the signal-independent condition. This assumption causes blind denoising techniques to suffer brightness shifting problems on images that are greatly corrupted by extreme noise such as salt-and-pepper noise. Moreover, most blind denoising methods require a random masking scheme for training to ensure the invarianc…
Rochester Institute of Technology（罗切斯特理工学院）；Chosun University（朝鲜大学）
Unpaired image denoising has achieved promising development over the last few years. Regardless of the performance, methods tend to heavily rely on underlying noise properties or any assumption which is not always practical. Alternatively, if we can ground the problem from a structural perspective rather than noise statistics, we can achieve a more robust solution. with such motivation, we propose a self-supervised denoising scheme that is unpaired and relies on spatial degradation followed by a regularized refinement. Our method shows considerable improvement over previous methods and exhibit…
This work identifies and addresses two important technical challenges in single-image super-resolution: (1) how to upsample an image without magnifying noise and (2) how to preserve large scale structure when upsampling. We summarize the techniques we developed for our second place entry in Track 1 (Bicubic Downsampling), seventh place entry in Track 2 (Realistic Adverse Conditions), and seventh place entry in Track 3 (Realistic difficult) in the 2018 NTIRE Super-Resolution Challenge. Furthermore, we present new neural network architectures that specifically address the two challenges listed a…
Institute of Automation, Chinese Academy of Sciences（中国科学院自动化研究所）；School of Artificial Intelligence, University of Chinese Academy of Sciences（中国科学院大学人工智能学院）；School of Future Technology, University of Chinese Academy of Sciences（中国科学院大学未来技术学院）
Self-supervised blind denoising for Poisson-Gaussian noise remains a challenging task. Pseudo-supervised pairs constructed from single noisy images re-corrupt the signal and degrade the performance. The visible blindspots solve the information loss in masked inputs. However, without explicitly noise sensing, mean square error as an objective function cannot adjust denoising intensities for dynamic noise levels, leading to noticeable residual noise. In this paper, we propose Blind2Sound, a simple yet effective approach to overcome residual noise in denoised images. The proposed adaptive re-visi…
Renmin University of China（中国人民大学）；Dalian University of Technology（大连理工大学）
In the last few years, image denoising has benefited a lot from the fast development of neural networks. However, the requirement of large amounts of noisy-clean image pairs for supervision limits the wide use of these models. Although there have been a few attempts in training an image denoising model with only single noisy images, existing self-supervised denoising approaches suffer from inefficient network training, loss of useful information, or dependence on noise modeling. In this paper, we present a very simple yet effective method named Neighbor2Neighbor to train an effective image den…
Recently, significant progress has been made on image denoising with strong supervision from large-scale datasets. However, obtaining well-aligned noisy-clean training image pairs for each specific scenario is complicated and costly in practice. Consequently, applying a conventional supervised denoising network on in-the-wild noisy inputs is not straightforward. Although several studies have challenged this problem without strong supervision, they rely on less practical assumptions and cannot be applied to practical situations directly. To address the aforementioned challenges, we propose a no…
FAU Erlangen-Nürnberg（埃尔朗根-纽伦堡大学）；Siemens Healthcare GmbH（西门子医疗有限公司）；Fraunhofer Institute for Ceramic Technologies and Systems IKTS（弗劳恩霍夫陶瓷技术与系统研究所IKTS）；Ewha Womans University（梨花女子大学）
Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple noisy realizations of similar images, e.g., from neighboring tomographic slices. However, those approaches fail to utilize the multiple contrasts that are routinely acquired in medical imaging modalities like MRI or dual-energy CT. In this work, we propose the new self-supervised training scheme Noise2Contrast that combines information from multiple measured …
University of California San Diego（加利福尼亚大学圣迭戈分校）；Tencent AI Lab（腾讯AI实验室）
The classic Monte Carlo path tracing can achieve high quality rendering at the cost of heavy computation. Recent works make use of deep neural networks to accelerate this process, by improving either low-resolution or fewer-sample rendering with super-resolution or denoising neural networks in post-processing. However, denoising and super-resolution have only been considered separately in previous work. We show in this work that Monte Carlo path tracing can be further accelerated by joint super-resolution and denoising (SRD) in post-processing. This new type of joint filtering allows only a lo…
Korea Advanced Institute of Science and Technology (KAIST)（韩国科学技术院）
Tweedie distributions are a special case of exponential dispersion models, which are often used in classical statistics as distributions for generalized linear models. Here, we reveal that Tweedie distributions also play key roles in modern deep learning era, leading to a distribution independent self-supervised image denoising formula without clean reference images. Specifically, by combining with the recent Noise2Score self-supervised image denoising approach and the saddle point approximation of Tweedie distribution, we can provide a general closed-form denoising formula that can be used fo…
California Polytechnic State University（加州州立理工大学）；University of Georgia（佐治亚大学）；Providence College（普罗维登斯学院）；University of Colorado Colorado Springs（科罗拉多大学科罗拉多斯普林斯分校）
We extend the blindspot model for self-supervised denoising to handle Poisson-Gaussian noise and introduce an improved training scheme that avoids hyperparameters and adapts the denoiser to the test data. Self-supervised models for denoising learn to denoise from only noisy data and do not require corresponding clean images, which are difficult or impossible to acquire in some application areas of interest such as low-light microscopy. We introduce a new training strategy to handle Poisson-Gaussian noise which is the standard noise model for microscope images. Our new strategy eliminates hyper…
SwinIA: Self-Supervised Blind-Spot Image Denoising without Convolutions
Institute of Computer Science, University of Tartu（塔尔图大学计算机科学学院）；CAIRO, Technical University of Applied Sciences Würzburg-Schweinfurt（维尔茨堡-施韦因富特应用技术大学CAIRO机构）
Harbin Institute of Technology（哈尔滨工业大学）；Peng Cheng Laboratory（鹏城实验室）
Significant progress has been made in self-supervised image denoising (SSID) in the recent few years. However, most methods focus on dealing with spatially independent noise, and they have little practicality on real-world sRGB images with spatially correlated noise. Although pixel-shuffle downsampling has been suggested for breaking the noise correlation, it breaks the original information of images, which limits the denoising performance. In this paper, we propose a novel perspective to solve this problem, i.e., seeking for spatially adaptive supervision for real-world sRGB image denoising. …
The Norwegian Colour and Visual Computing Laboratory（挪威色彩与视觉计算实验室）；NTNU（挪威科技大学）
Deep learning algorithms have demonstrated state-of-the-art performance in various tasks of image restoration. This was made possible through the ability of CNNs to learn from large exemplar sets. However, the latter becomes an issue for hyperspectral image processing where datasets commonly consist of just a few images. In this work, we propose a new approach to denoising, inpainting, and super-resolution of hyperspectral image data using intrinsic properties of a CNN without any training. The performance of the given algorithm is shown to be comparable to the performance of trained networks,…
The Chinese University of Hong Kong（香港中文大学）；SmartMore
Despite the quality improvement brought by the recent methods, video super-resolution (SR) is still very challenging, especially for videos that are low-light and noisy. The current best solution is to subsequently employ best models of video SR, denoising, and illumination enhancement, but doing so often lowers the image quality, due to the inconsistency between the models. This paper presents a new parametric representation called the Deep Parametric 3D Filters (DP3DF), which incorporates local spatiotemporal information to enable simultaneous denoising, illumination enhancement, and SR effi…
Korea Advanced Institute of Science and Technology (KAIST)（韩国科学技术院）；Chung-Ang University Hospital（中央大学医院）；Chung-Ang University College of Medicine（中央大学医学院）
Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community as a general subject. However, recent deep neural network-based approaches mostly rely on the minimum mean squared error (MMSE) estimates, which tend to produce a blurred output. Moreover, such models suffer when deployed in real-world sitautions: out-of-distribution data, and complex noise distributions that deviate from the usual parametric noise models. In…
Hanyang University（汉阳大学）；NAVER LABS（NAVER实验室）；Chungnam National University（忠南国立大学）；SK T-Brain
In this study, we propose a simple and effective fine-tuning algorithm called "restore-from-restored", which can greatly enhance the performance of fully pre-trained image denoising networks. Many supervised denoising approaches can produce satisfactory results using large external training datasets. However, these methods have limitations in using internal information available in a given test image. By contrast, recent self-supervised approaches can remove noise in the input image by utilizing information from the specific test input. However, such methods show relatively lower performance o…
Investigating Self-Supervised Image Denoising with Denaturation
Institute of Science Tokyo（东京科学研究所）；Fujitsu Limited（富士通有限公司）；RIKEN Center for Computational Science（理化学研究所计算科学中心）；RIKEN Center for Advanced Intelligence Project（理化学研究所先进智能项目中心）
Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to noise. Recently, a few self-supervised deep learning (DL) denoising methods have been proposed. However, the training efficiency and denoising performance of existing methods are relatively low in real scene noise removal. To address this issue, this paper proposed self-supervised image denoising method Noise2SR (N2SR) to train a simple and effective image den…
Next-Scale Prediction: A Self-Supervised Approach for Real-World Image Denoising
College of Computer Science, Sichuan University（四川大学计算机科学学院）；National Key Laboratory of Fundamental Algorithms and Models for Engineering Numerical Simulation, Sichuan University（四川大学工程数值模拟基础算法与模型全国重点实验室）
Computer Vision Lab, ETH Zurich（苏黎世联邦理工学院计算机视觉实验室）
We propose a deep reparametrization of the maximum a posteriori formulation commonly employed in multi-frame image restoration tasks. Our approach is derived by introducing a learned error metric and a latent representation of the target image, which transforms the MAP objective to a deep feature space. The deep reparametrization allows us to directly model the image formation process in the latent space, and to integrate learned image priors into the prediction. Our approach thereby leverages the advantages of deep learning, while also benefiting from the principled multi-frame fusion provide…
We present a method for supervised learning of sparsity-promoting regularizers for image denoising. Sparsity-promoting regularization is a key ingredient in solving modern image reconstruction problems; however, the operators underlying these regularizers are usually either designed by hand or learned from data in an unsupervised way. The recent success of supervised learning (mainly convolutional neural networks) in solving image reconstruction problems suggests that it could be a fruitful approach to designing regularizers. As a first experiment in this direction, we propose to denoise image…
Supervised neural networks are known to achieve excellent results in various image restoration tasks. However, such training requires datasets composed of pairs of corrupted images and their corresponding ground truth targets. Unfortunately, such data is not available in many applications. For the task of image denoising in which the noise statistics is unknown, several self-supervised training methods have been proposed for overcoming this difficulty. Some of these require knowledge of the noise model, while others assume that the contaminating noise is uncorrelated, both assumptions are too …
With the advent of advances in self-supervised learning, paired clean-noisy data are no longer required in deep learning-based image denoising. However, existing blind denoising methods still require the assumption with regard to noise characteristics, such as zero-mean noise distribution and pixel-wise noise-signal independence; this hinders wide adaptation of the method in the medical domain. On the other hand, unpaired learning can overcome limitations related to the assumption on noise characteristics, which makes it more feasible for collecting the training data in real-world scenarios. I…
Politecnico di Milano（米兰理工大学）；University of Twente（特温特大学）；University of Bath（巴斯大学）；University of Cambridge（剑桥大学）
4D flow MRI is a non-invasive imaging method that can measure blood flow velocities over time. However, the velocity fields detected by this technique have limitations due to low resolution and measurement noise. Coordinate-based neural networks have been researched to improve accuracy, with SIRENs being suitable for super-resolution tasks. Our study investigates SIRENs for time-varying 3-directional velocity fields measured in the aorta by 4D flow MRI, achieving denoising and super-resolution. We trained our method on voxel coordinates and benchmarked our approach using synthetic measurements…
We propose a new grayscale image denoiser, dubbed as Neural Affine Image Denoiser (Neural AIDE), which utilizes neural network in a novel way. Unlike other neural network based image denoising methods, which typically apply simple supervised learning to learn a mapping from a noisy patch to a clean patch, we formulate to train a neural network to learn an \emph{affine} mapping that gets applied to a noisy pixel, based on its context. Our formulation enables both supervised training of the network from the labeled training dataset and adaptive fine-tuning of the network parameters using the giv…
Centrum Wiskunde & Informatica（荷兰国家数学与计算机科学研究中心）；Leiden Institute of Advanced Computer Science, Leiden Universiteit（莱顿大学高级计算机科学研究所）
Recovering a high-quality image from noisy indirect measurements is an important problem with many applications. For such inverse problems, supervised deep convolutional neural network (CNN)-based denoising methods have shown strong results, but the success of these supervised methods critically depends on the availability of a high-quality training dataset of similar measurements. For image denoising, methods are available that enable training without a separate training dataset by assuming that the noise in two different pixels is uncorrelated. However, this assumption does not hold for inve…
Nankai University（南开大学）；Xi’an Jiaotong University（西安交通大学）；Inception Institute of Artificial Intelligence (IIAI)（人工智能 inception 研究院）；Mohamed bin Zayed University of Artificial Intelligence (MBZUAI)（穆罕默德·本·扎耶德人工智能大学）；Chongqing University（重庆大学）
Supervised deep networks have achieved promisingperformance on image denoising, by learning image priors andnoise statistics on plenty pairs of noisy and clean images. Unsupervised denoising networks are trained with only noisy images. However, for an unseen corrupted image, both supervised andunsupervised networks ignore either its particular image prior, the noise statistics, or both. That is, the networks learned from external images inherently suffer from a domain gap problem: the image priors and noise statistics are very different between the training and test images. This problem become…
This paper evaluates the performance of supervised and unsupervised deep learning models for denoising positron emission tomography (PET) images in the presence of reduced acquisition times. Our experiments consider 212 studies (56908 images), and evaluate the models using 2D (RMSE, SSIM) and 3D (SUVpeak and SUVmax error for the regions of interest) metrics. It was shown that, in contrast to previous studies, supervised models (ResNet, Unet, SwinIR) outperform unsupervised models (pix2pix GAN and CycleGAN with ResNet backbone and various auxiliary losses) in the reconstruction of 2D PET images…
Johns Hopkins University（约翰斯·霍普金斯大学）；The Chinese University of Hong Kong, Shenzhen（香港中文大学（深圳））
The ultimate aim of image restoration like denoising is to find an exact correlation between the noisy and clear image domains. But the optimization of end-to-end denoising learning like pixel-wise losses is performed in a sample-to-sample manner, which ignores the intrinsic correlation of images, especially semantics. In this paper, we introduce the Deep Semantic Statistics Matching (D2SM) Denoising Network. It exploits semantic features of pretrained classification networks, then it implicitly matches the probabilistic distribution of clear images at the semantic feature space. By learning t…
